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Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

Molecular cell, 2010-12, Vol.40 (6), p.893-904

2010

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MicroRNA-195 Regulates Metabolism in Failing Myocardium Via Alterations in Sirtuin 3 Expression and Mitochondrial Protein Acetylation

Circulation (New York, N.Y.), 2018-05, Vol.137 (19), p.2052-2067

2018

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Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway

Journal of the American Heart Association, 2017-09, Vol.6 (9), p.n/a

2017

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Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis

Cancer cell, 2019-06, Vol.35 (6), p.916-931.e9

2019

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Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (16), p.6601-6606

2013

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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Nature (London), 2010-03, Vol.464 (7285), p.121-125

2010

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SIRT3 deficiency is resistant to autophagy‐dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels

Journal of cellular physiology, 2020-11, Vol.235 (11), p.8839-8851

2020

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Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure

Circulation research, 2020-09, Vol.127 (8), p.1094-1108

2020

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Alterations in mitochondrial dynamics with age‐related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility

Aging cell, 2021-07, Vol.20 (7), p.e13419-n/a

2021

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Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice

American journal of physiology. Heart and circulatory physiology, 2016-04, Vol.310 (8), p.H962-H972

2016

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SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis

Cell death & disease, 2018-09, Vol.9 (10), p.997-14, Article 997

2018

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Berberine alleviates nonalcoholic fatty liver induced by a high‐fat diet in mice by activating SIRT3

The FASEB journal, 2019-06, Vol.33 (6), p.7289-7300

2019

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SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts

American journal of physiology. Heart and circulatory physiology, 2014-06, Vol.306 (12), p.H1602-H1609

2014

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Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction

Journal of molecular and cellular cardiology, 2017-11, Vol.112, p.104-113

2017

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Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

Aging (Albany, NY.), 2010-12, Vol.2 (12), p.914-923

2010

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NAD deficiency contributes to progressive kidney disease in HIV-nephropathy mice

American journal of physiology. Renal physiology, 2024-09, Vol.327 (3), p.F450-F462

2024

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Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction

Circulation (New York, N.Y.), 2024-09, Vol.150 (11), p.867-883

2024

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Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

Oncogene, 2020-02, Vol.39 (8), p.1619-1633

2020

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Sirtuin 3 Deficiency Accelerates Hypertensive Cardiac Remodeling by Impairing Angiogenesis

Journal of the American Heart Association, 2017-08, Vol.6 (8), p.n/a

2017

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High‐fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss

Journal of cellular and molecular medicine, 2015-08, Vol.19 (8), p.1847-1856

2015

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Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity

Cardiovascular research, 2018-07, Vol.114 (8), p.1178-1188

2018

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Ablation of SIRT3 Causes Coronary Microvascular Dysfunction and Impairs Cardiac Recovery Post Myocardial Ischemia

International journal of cardiology, 2016-07, Vol.215, p.349-357

2016

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SIRT3 deficiency delays diabetic skin wound healing via oxidative stress and necroptosis enhancement

Journal of cellular and molecular medicine, 2020-04, Vol.24 (8), p.4415-4427

2020

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Sirtuin 3 silencing impairs mitochondrial biogenesis and metabolism in colon cancer cells

American Journal of Physiology: Cell Physiology, 2019-08, Vol.317 (2), p.C398-C404

2019

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SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation

Theranostics, 2021-01, Vol.11 (8), p.3981-3995

2021

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Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

MicroRNA-195 Regulates Metabolism in Failing Myocardium Via Alterations in Sirtuin 3 Expression and Mitochondrial Protein Acetylation

Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway

Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

SIRT3 deficiency is resistant to autophagy‐dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels

Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure

Alterations in mitochondrial dynamics with age‐related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility

Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice

SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis

Berberine alleviates nonalcoholic fatty liver induced by a high‐fat diet in mice by activating SIRT3

SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts

Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

NAD deficiency contributes to progressive kidney disease in HIV-nephropathy mice

Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

Sirtuin 3 Deficiency Accelerates Hypertensive Cardiac Remodeling by Impairing Angiogenesis

High‐fat diet induces cardiac remodelling and dysfunction: assessment of the role played by SIRT3 loss

Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity

Ablation of SIRT3 Causes Coronary Microvascular Dysfunction and Impairs Cardiac Recovery Post Myocardial Ischemia

SIRT3 deficiency delays diabetic skin wound healing via oxidative stress and necroptosis enhancement

Sirtuin 3 silencing impairs mitochondrial biogenesis and metabolism in colon cancer cells

SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation

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