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Natural sesquiterpene quinone/quinols: chemistry, biological activity, and synthesis

Natural product reports, 2023-03, Vol.4 (3), p.718-749

2023

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Divergent total synthesis of marine meroterpenoids (+)-dysidavarones A–C

Chinese chemical letters, 2024-03, Vol.35 (3), p.108338, Article 108338

2024

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Fluorescent image-based high-content screening of extracts of natural resources for cell cycle inhibitors and identification of a new sesquiterpene quinone from the sponge, Dactylospongia metachromia

Bioorganic & medicinal chemistry, 2021-02, Vol.31, p.115968-115968, Article 115968

2021

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Practical and Scalable Total Syntheses of (+)-Dysidavarones A–C

Synlett, 2023-02, Vol.35 (5), p.582-585

2023

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Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone

Marine drugs, 2020-02, Vol.18 (2), p.112

2020

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Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity

International journal of molecular sciences, 2020-08, Vol.21 (17), p.6021

2020

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In silico Study of the Pharmacologic Properties and Cytotoxicity Pathways in Cancer Cells of Various Indolylquinone Analogues of Perezone

Molecules (Basel, Switzerland), 2017-06, Vol.22 (7), p.1060

2017

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Discovery of nitrogenous sesquiterpene quinone derivatives from sponge Dysidea septosa with anti-inflammatory activity in vivo zebrafish model

Bioorganic chemistry, 2020-01, Vol.94, p.103435, Article 103435

2020

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Dysideanones F—G and dysiherbols D—E, unusual sesquiterpene quinones with rearranged skeletons from the marine sponge Dysidea avara

Chinese journal of natural medicines, 2022-02, Vol.20 (2), p.148-154

2022

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Green Approach Extraction of Perezone from the Roots of Acourtia platyphilla (A. Grey): A Comparison of Four Activating Modes and Supercritical Carbon Dioxide

Molecules (Basel, Switzerland), 2019-08, Vol.24 (17), p.3035

2019

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Divergent total synthesis of sesquiterpene (hydro)quinone meroterpenoids dysideanones A and E–G

Chinese chemical letters, 2024-04, p.109915, Article 109915

2024

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High variability of perezone content in rhizomes of Acourtia cordata wild plants, environmental factors related, and proteomic analysis

PeerJ (San Francisco, CA), 2023-11, Vol.11, p.e16136-e16136, Article e16136

2023

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A Timeline of Perezone, the First Isolated Secondary Metabolite in the New World, Covering the Period from 1852 to 2020

Progress in the Chemistry of Organic Natural Products 116, 2021, Vol.116, p.67-133

2021

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A new cytotoxic sesquiterpene quinone produced by Penicillium sp. F00120 isolated from a deep sea sediment sample

Marine drugs, 2012-01, Vol.10 (1), p.106-115

2012

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An overview of odoriferous marine seaweeds of the Dictyopteris genus: insights into their chemical diversity, biological potential and ecological roles

Revista brasileira de farmacognosia, 2018-03, Vol.28 (2), p.243-260

2018

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Three new sesquiterpene aminoquinones from a Vietnamese Spongia sp. and their biological activities

Journal of natural medicines, 2018, Vol.72 (1), p.298-303

2018

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A novel sesquiterpene quinone from Hainan sponge Dysidea villosa

Bioorganic & medicinal chemistry letters, 2009-01, Vol.19 (2), p.390-392

2009

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Ilimaquinone Induces Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma Cells

Biomedicines, 2020-08, Vol.8 (9), p.296

2020

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Exerting DNA Damaging Effects of the Ilimaquinones through the Active Hydroquinone Species

Scientia pharmaceutica, 2021-06, Vol.89 (2), p.26

2021

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Quinone/Hydroquinone Sesquiterpenes

Mini-reviews in organic chemistry, 2010-08, Vol.7 (3), p.230-254

2010

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Popolohuanones G – I, Dimeric Sesquiterpene Quinones with IL‐6 Inhibitory Activity from the Marine Sponge Dactylospongia elegans

Chemistry & biodiversity, 2018-06, Vol.15 (6), p.e1800078-n/a

2018

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The Role of Spongia sp. in the Discovery of Marine Lead Compounds

Marine Drugs, 2016-07, Vol.14 (8), p.139

2016

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Neopetrosiquinones A and B, sesquiterpene benzoquinones isolated from the deep-water sponge Neopetrosia cf. proxima

Bioorganic & medicinal chemistry, 2011-11, Vol.19 (22), p.6599-6603

2011

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Puupehenone, a Marine-Sponge-Derived Sesquiterpene Quinone, Potentiates the Antifungal Drug Caspofungin by Disrupting Hsp90 Activity and the Cell Wall Integrity Pathway

mSphere, 2020-01, Vol.5 (1)

2020

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Myrothecols g and h, two new analogues of the marine-derived quinone sesquiterpene penicilliumin A

Marine drugs, 2015-05, Vol.13 (6), p.3360-3367

2015

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Natural sesquiterpene quinone/quinols: chemistry, biological activity, and synthesis

Divergent total synthesis of marine meroterpenoids (+)-dysidavarones A–C

Fluorescent image-based high-content screening of extracts of natural resources for cell cycle inhibitors and identification of a new sesquiterpene quinone from the sponge, Dactylospongia metachromia

Practical and Scalable Total Syntheses of (+)-Dysidavarones A–C

Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone

Ilimaquinone Induces the Apoptotic Cell Death of Cancer Cells by Reducing Pyruvate Dehydrogenase Kinase 1 Activity

In silico Study of the Pharmacologic Properties and Cytotoxicity Pathways in Cancer Cells of Various Indolylquinone Analogues of Perezone

Discovery of nitrogenous sesquiterpene quinone derivatives from sponge Dysidea septosa with anti-inflammatory activity in vivo zebrafish model

Dysideanones F—G and dysiherbols D—E, unusual sesquiterpene quinones with rearranged skeletons from the marine sponge Dysidea avara

Green Approach Extraction of Perezone from the Roots of Acourtia platyphilla (A. Grey): A Comparison of Four Activating Modes and Supercritical Carbon Dioxide

Divergent total synthesis of sesquiterpene (hydro)quinone meroterpenoids dysideanones A and E–G

High variability of perezone content in rhizomes of Acourtia cordata wild plants, environmental factors related, and proteomic analysis

A Timeline of Perezone, the First Isolated Secondary Metabolite in the New World, Covering the Period from 1852 to 2020

A new cytotoxic sesquiterpene quinone produced by Penicillium sp. F00120 isolated from a deep sea sediment sample

An overview of odoriferous marine seaweeds of the Dictyopteris genus: insights into their chemical diversity, biological potential and ecological roles

Three new sesquiterpene aminoquinones from a Vietnamese Spongia sp. and their biological activities

A novel sesquiterpene quinone from Hainan sponge Dysidea villosa

Ilimaquinone Induces Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma Cells

Exerting DNA Damaging Effects of the Ilimaquinones through the Active Hydroquinone Species

Quinone/Hydroquinone Sesquiterpenes

Popolohuanones G – I, Dimeric Sesquiterpene Quinones with IL‐6 Inhibitory Activity from the Marine Sponge Dactylospongia elegans

The Role of Spongia sp. in the Discovery of Marine Lead Compounds

Neopetrosiquinones A and B, sesquiterpene benzoquinones isolated from the deep-water sponge Neopetrosia cf. proxima

Puupehenone, a Marine-Sponge-Derived Sesquiterpene Quinone, Potentiates the Antifungal Drug Caspofungin by Disrupting Hsp90 Activity and the Cell Wall Integrity Pathway

Myrothecols g and h, two new analogues of the marine-derived quinone sesquiterpene penicilliumin A

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