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Pharmacokinetics and pharmacodynamics of intranasally administered selegiline nanoparticles with improved brain delivery in Parkinson's disease

Nanomedicine, 2018-11, Vol.14 (8), p.2609-2618

2018

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Selegiline ameliorated dyslipidemia and hepatic steatosis in high-fat diet mice

International immunopharmacology, 2023-04, Vol.117, p.109901-109901, Article 109901

2023

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Evidence that formulations of the selective MAO-B inhibitor, selegiline, which bypass first-pass metabolism, also inhibit MAO-A in the human brain

Neuropsychopharmacology (New York, N.Y.), 2015-02, Vol.40 (3), p.650-657

2015

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The significance of selegiline

Molecular psychiatry, 2016-11, Vol.21 (11), p.1499

Miklya, I

2016

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Rasagiline: a novel anti-Parkinsonian monoamine oxidase-B inhibitor with neuroprotective activity

Progress in neurobiology, 2010-11, Vol.92 (3), p.330-344

2010

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Brain targeted delivery of mucoadhesive thermosensitive nasal gel of selegiline hydrochloride for treatment of Parkinson's disease

Journal of drug targeting, 2018-02, Vol.26 (2), p.150-161

2018

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Comprehensive review of rasagiline, a second-generation monoamine oxidase inhibitor, for the treatment of Parkinson's Disease

Clinical therapeutics, 2007-09, Vol.29 (9), p.1825-1849

2007

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Development and evaluation of buccal films impregnated with selegiline-loaded nanospheres

Drug delivery, 2016-09, Vol.23 (7), p.2154-2162

2016

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Concomitant use of monoamine oxidase inhibitor and tyrosine in parenteral nutrition

European journal of clinical nutrition, 2024-03, Vol.78 (3), p.274-276

2024

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Low Dose Betahistine in Combination With Selegiline Increases Cochlear Blood Flow in Guinea Pigs

Annals of otology, rhinology & laryngology, 2023-05, Vol.132 (5), p.519-526

2023

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Box-Behnken experimental design for preparation and optimization of the intranasal gels of selegiline hydrochloride

Drug development and industrial pharmacy, 2018-10, Vol.44 (10), p.1613-1621

2018

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Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease

Nature communications, 2017-04, Vol.8 (1), p.14727-14727, Article 14727

2017

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Transdermal delivery of selegiline from alginate–Pluronic composite thermogels

International journal of pharmaceutics, 2011-08, Vol.415 (1), p.119-128

2011

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Involvement of D1 and D2 dopamine receptors in the antidepressant-like effects of selegiline in maternal separation model of mouse

Physiology & behavior, 2016-09, Vol.163, p.107-114

2016

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N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic Change

Molecular neurobiology, 2016-11, Vol.53 (9), p.6251-6269

2016

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Effect of selegiline as a monomine oxidase B inhibitor on the expression of neurotrophin mRNA levels in a contusion rat model of spinal cord injury

Neurological research (New York), 2023-03, Vol.45 (3), p.241-247

2023

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The Monoamine Oxidase-B Inhibitor Selegiline Does Not Affect 18 F-Florzolotau Uptake in Patients with Progressive Supranuclear Palsy: A Longitudinal Case Series

Movement disorders, 2023-04, Vol.38 (4), p.705-707

2023

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Longevity study with low doses of selegiline/(−)-deprenyl and (2R)-1-(1-benzofuran-2-yl)-N-propylpentane-2-amine (BPAP)

Life sciences (1973), 2016-12, Vol.167, p.32-38

2016

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Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease: Past, Present, and Future

Journal of Parkinson's disease, 2022-01, Vol.12 (2), p.477-493

2022

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Classics in Chemical Neuroscience: Selegiline, Isocarboxazid, Phenelzine, and Tranylcypromine

ACS chemical neuroscience, 2023-12, Vol.14 (23), p.4064-4075

2023

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Inhibitors of MAO-A and MAO-B in Psychiatry and Neurology

Frontiers in pharmacology, 2016-10, Vol.7, p.340-340

2016

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Pharmacological evaluation of nasal delivery of selegiline hydrochloride-loaded thiolated chitosan nanoparticles for the treatment of depression

Artificial cells, nanomedicine, and biotechnology, 2016-05, Vol.44 (3), p.865-877

2016

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Simultaneous determination of citalopram and selegiline using an efficient electrochemical sensor based on ZIF-8 decorated with RGO and g-C3N4 in real samples

Analytica chimica acta, 2022-04, Vol.1203, p.339662-339662, Article 339662

2022

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Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness

British journal of pharmacology, 2006-01, Vol.147 (S1), p.S287-S296

2006

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Appraisal of Transdermal Water-in-Oil Nanoemulgel of Selegiline HCl for the Effective Management of Parkinson’s Disease: Pharmacodynamic, Pharmacokinetic, and Biochemical Investigations

AAPS PharmSciTech, 2018-02, Vol.19 (2), p.573-589

2018

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Pharmacokinetics and pharmacodynamics of intranasally administered selegiline nanoparticles with improved brain delivery in Parkinson's disease

Selegiline ameliorated dyslipidemia and hepatic steatosis in high-fat diet mice

Evidence that formulations of the selective MAO-B inhibitor, selegiline, which bypass first-pass metabolism, also inhibit MAO-A in the human brain

The significance of selegiline

Rasagiline: a novel anti-Parkinsonian monoamine oxidase-B inhibitor with neuroprotective activity

Brain targeted delivery of mucoadhesive thermosensitive nasal gel of selegiline hydrochloride for treatment of Parkinson's disease

Comprehensive review of rasagiline, a second-generation monoamine oxidase inhibitor, for the treatment of Parkinson's Disease

Development and evaluation of buccal films impregnated with selegiline-loaded nanospheres

Concomitant use of monoamine oxidase inhibitor and tyrosine in parenteral nutrition

Low Dose Betahistine in Combination With Selegiline Increases Cochlear Blood Flow in Guinea Pigs

Box-Behnken experimental design for preparation and optimization of the intranasal gels of selegiline hydrochloride

Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease

Transdermal delivery of selegiline from alginate–Pluronic composite thermogels

Involvement of D1 and D2 dopamine receptors in the antidepressant-like effects of selegiline in maternal separation model of mouse

N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic Change

Effect of selegiline as a monomine oxidase B inhibitor on the expression of neurotrophin mRNA levels in a contusion rat model of spinal cord injury

The Monoamine Oxidase-B Inhibitor Selegiline Does Not Affect 18 F-Florzolotau Uptake in Patients with Progressive Supranuclear Palsy: A Longitudinal Case Series

Longevity study with low doses of selegiline/(−)-deprenyl and (2R)-1-(1-benzofuran-2-yl)-N-propylpentane-2-amine (BPAP)

Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease: Past, Present, and Future

Classics in Chemical Neuroscience: Selegiline, Isocarboxazid, Phenelzine, and Tranylcypromine

Inhibitors of MAO-A and MAO-B in Psychiatry and Neurology

Pharmacological evaluation of nasal delivery of selegiline hydrochloride-loaded thiolated chitosan nanoparticles for the treatment of depression

Simultaneous determination of citalopram and selegiline using an efficient electrochemical sensor based on ZIF-8 decorated with RGO and g-C3N4 in real samples

Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness

Appraisal of Transdermal Water-in-Oil Nanoemulgel of Selegiline HCl for the Effective Management of Parkinson’s Disease: Pharmacodynamic, Pharmacokinetic, and Biochemical Investigations

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