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NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system

EMBO reports, 2020-03, Vol.21 (3), p.e48902-e48902

2020

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Proximity labeling reveals dynamic changes in the SQSTM1 protein network

The Journal of biological chemistry, 2024-09, Vol.300 (9), p.107621, Article 107621

2024

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SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity

Autophagy, 2020-11, Vol.16 (11), p.1949-1973

2020

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Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cells

Cell death & disease, 2013-03, Vol.4 (3), p.e550-e550

2013

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SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling

Neurobiology of aging, 2021-02, Vol.98, p.10-20

2021

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P62/SQSTM1 mediates the autophagy-lysosome degradation of CDK2 protein undergoing PI3Kα/AKT T308 inhibition

Biochemical and biophysical research communications, 2022-10, Vol.627, p.5-11

2022

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Selective autophagy receptor SQSTM1/ p62 inhibits Seneca Valley virus replication by targeting viral VP1 and VP3

Autophagy, 2021-11, Vol.17 (11), p.3763-3775

2021

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p62/SQSTM1: ‘Jack of all trades’ in health and cancer

The FEBS journal, 2019-01, Vol.286 (1), p.8-23

2019

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The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity

Autophagy, 2020-04, Vol.16 (4), p.698-708

2020

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Abnormal expression of autophagy proteins in the duodenum of patients with functional dyspepsia: A preliminary study

Arab journal of gastroenterology, 2024-09

2024

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TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation

Autophagy, 2021-09, Vol.17 (9), p.2549-2564

2021

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Monitoring and Measuring Autophagy

International journal of molecular sciences, 2017-08, Vol.18 (9), p.1865

2017

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Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

The EMBO journal, 2018-04, Vol.37 (8), p.n/a

2018

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Regulation of the Keap1–Nrf2 pathway by p62/SQSTM1

Current opinion in toxicology, 2016-12, Vol.1, p.54-61

2016

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SQSTM1-dependent autophagic degradation of PKM2 inhibits the production of mature IL1B/IL-1β and contributes to LIPUS-mediated anti-inflammatory effect

Autophagy, 2020-07, Vol.16 (7), p.1262-1278

2020

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Differential regulation of autophagy during metabolic stress in astrocytes and neurons

Autophagy, 2020-09, Vol.16 (9), p.1651-1667

2020

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Autophagy and ALS: mechanistic insights and therapeutic implications

Autophagy, 2022-02, Vol.18 (2), p.254-282

2022

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The ICP0 Protein of Herpes Simplex Virus 1 (HSV-1) Downregulates Major Autophagy Adaptor Proteins Sequestosome 1 and Optineurin during the Early Stages of HSV-1 Infection

Journal of virology, 2019-11, Vol.93 (21)

2019

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p62/SQSTM1 - steering the cell through health and disease

Journal of cell science, 2018-11, Vol.131 (21)

2018

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p62-mediated phase separation at the intersection of the ubiquitin-proteasome system and autophagy

Journal of cell science, 2018-10, Vol.131 (19)

2018

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Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers

Autophagy, 2018-04, Vol.14 (4), p.619-636

2018

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Lipotoxicity reduces DDX58/Rig-1 expression and activity leading to impaired autophagy and cell death

Autophagy, 2022-01, Vol.18 (1), p.142-160

2022

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Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis

Autophagy, 2023-06, Vol.19 (6), p.1733-1744

2023

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Selective Autophagy Receptor p62/SQSTM1, a Pivotal Player in Stress and Aging

Frontiers in cell and developmental biology, 2022-02, Vol.10, p.793328

2022

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Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice

Journal of hepatology, 2016-08, Vol.65 (2), p.354-362

2016

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NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system

Proximity labeling reveals dynamic changes in the SQSTM1 protein network

SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity

Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cells

SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling

P62/SQSTM1 mediates the autophagy-lysosome degradation of CDK2 protein undergoing PI3Kα/AKT T308 inhibition

Selective autophagy receptor SQSTM1/ p62 inhibits Seneca Valley virus replication by targeting viral VP1 and VP3

p62/SQSTM1: ‘Jack of all trades’ in health and cancer

The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity

Abnormal expression of autophagy proteins in the duodenum of patients with functional dyspepsia: A preliminary study

TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation

Monitoring and Measuring Autophagy

Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

Regulation of the Keap1–Nrf2 pathway by p62/SQSTM1

SQSTM1-dependent autophagic degradation of PKM2 inhibits the production of mature IL1B/IL-1β and contributes to LIPUS-mediated anti-inflammatory effect

Differential regulation of autophagy during metabolic stress in astrocytes and neurons

Autophagy and ALS: mechanistic insights and therapeutic implications

The ICP0 Protein of Herpes Simplex Virus 1 (HSV-1) Downregulates Major Autophagy Adaptor Proteins Sequestosome 1 and Optineurin during the Early Stages of HSV-1 Infection

p62/SQSTM1 - steering the cell through health and disease

p62-mediated phase separation at the intersection of the ubiquitin-proteasome system and autophagy

Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers

Lipotoxicity reduces DDX58/Rig-1 expression and activity leading to impaired autophagy and cell death

Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis

Selective Autophagy Receptor p62/SQSTM1, a Pivotal Player in Stress and Aging

Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice

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