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ATF7IP regulates SETDB1 nuclear localization and increases its ubiquitination

EMBO reports, 2019-12, Vol.20 (12), p.e48297-e48297

2019

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SETDB1 regulates SMAD7 expression for breast cancer metastasis

BMB reports, 2019-02, Vol.52 (2), p.139-144

2019

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Cooperation between IRTKS and deubiquitinase OTUD4 enhances the SETDB1-mediated H3K9 trimethylation that promotes tumor metastasis via suppressing E-cadherin expression

Cancer letters, 2023-10, Vol.575, p.216404-216404, Article 216404

2023

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Roles of the histone methyltransferase SET domain bifurcated 1 in epithelial cells during tooth development

Archives of oral biology, 2025-01, Vol.169, p.106094, Article 106094

2025

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Alcoholic Setdb1 suppression promotes hepatosteatosis in mice by strengthening Plin2

Metabolism, clinical and experimental, 2023-09, Vol.146, p.155656-155656, Article 155656

2023

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Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure

Cancer cell, 2017-08, Vol.32 (2), p.221-237.e13

2017

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Knockout of FosB gene changes drug sensitivity and invasion activity via the regulation of Bcl-2, E-cadherin, β-catenin, and vimentin expression

Biochemical and biophysical research communications, 2021-08, Vol.567, p.131-137

2021

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MiR‐7, Inhibited Indirectly by LincRNA HOTAIR, Directly Inhibits SETDB1 and Reverses the EMT of Breast Cancer Stem Cells by Downregulating the STAT3 Pathway

Stem cells (Dayton, Ohio), 2014-11, Vol.32 (11), p.2858-2868

2014

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Necroptosis contributes to the intestinal toxicity of deoxynivalenol and is mediated by methyltransferase SETDB1

Journal of hazardous materials, 2024-08, Vol.474, p.134601, Article 134601

2024

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The Essential Function of SETDB1 in Homologous Chromosome Pairing and Synapsis during Meiosis

Cell reports (Cambridge), 2021-01, Vol.34 (1), p.108575-108575, Article 108575

2021

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SETDB1 is essential for mouse primordial germ cell fate determination by ensuring BMP signaling

Development (Cambridge), 2018-12, Vol.145 (23)

2018

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Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells

Genes & development, 2014-09, Vol.28 (18), p.2041-2055

2014

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Structure‐Guided Discovery of a Potent and Selective Cell‐Active Inhibitor of SETDB1 Tudor Domain

Angewandte Chemie International Edition, 2021-04, Vol.60 (16), p.8760-8765

International ed. in English, 2021

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Silencing of endogenous retroviruses by heterochromatin

Cellular and molecular life sciences : CMLS, 2017-06, Vol.74 (11), p.2055-2065

2017

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SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation

Cell reports (Cambridge), 2024-08, Vol.43 (8), p.114536, Article 114536

2024

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Co-transcriptional genome surveillance by HUSH is coupled to termination machinery

Molecular cell, 2023-05, Vol.83 (10), p.1623-1639.e8

2023

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SETDB1-Mediated Silencing of Retroelements

Viruses, 2020-05, Vol.12 (6), p.596

2020

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Transcription factor FOXM1 promotes hepatocellular carcinoma malignant progression through activation of the WNT pathway by binding to SETDB1

Tissue & cell, 2023-10, Vol.84, p.102186-102186, Article 102186

2023

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Roles of the histone methyltransferase SET domain bifurcated 1 in epithelial cells during tooth development

Archives of oral biology, 2024-09, Vol.165, p.106026, Article 106026

2024

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Transcriptome-wide Dynamics of m6A mRNA Methylation During Porcine Spermatogenesis

Genomics, proteomics & bioinformatics, 2023-08, Vol.21 (4), p.729-741

2023

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Mechanism of SUMOylation-Mediated Regulation of Type I IFN Expression

Journal of molecular biology, 2023-03, Vol.435 (5), p.167968-167968, Article 167968

2023

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Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46

Structure (London), 2024-03, Vol.32 (3), p.304-315.e5

2024

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SETDB1, an H3K9-specific methyltransferase: An attractive epigenetic target to combat cancer

Drug discovery today, 2024-05, Vol.29 (5), p.103982, Article 103982

2024

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Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

The Journal of biological chemistry, 2022-07, Vol.298 (7), p.102106-102106, Article 102106

2022

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Histone methyltransferase SETDB1 inhibits TGF-β-induced epithelial–mesenchymal transition in pulmonary fibrosis by regulating SNAI1 expression and the ferroptosis signaling pathway

Archives of biochemistry and biophysics, 2022-01, Vol.715, p.109087, Article 109087

2022

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ATF7IP regulates SETDB1 nuclear localization and increases its ubiquitination

SETDB1 regulates SMAD7 expression for breast cancer metastasis

Cooperation between IRTKS and deubiquitinase OTUD4 enhances the SETDB1-mediated H3K9 trimethylation that promotes tumor metastasis via suppressing E-cadherin expression

Roles of the histone methyltransferase SET domain bifurcated 1 in epithelial cells during tooth development

Alcoholic Setdb1 suppression promotes hepatosteatosis in mice by strengthening Plin2

Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure

Knockout of FosB gene changes drug sensitivity and invasion activity via the regulation of Bcl-2, E-cadherin, β-catenin, and vimentin expression

MiR‐7, Inhibited Indirectly by LincRNA HOTAIR, Directly Inhibits SETDB1 and Reverses the EMT of Breast Cancer Stem Cells by Downregulating the STAT3 Pathway

Necroptosis contributes to the intestinal toxicity of deoxynivalenol and is mediated by methyltransferase SETDB1

The Essential Function of SETDB1 in Homologous Chromosome Pairing and Synapsis during Meiosis

SETDB1 is essential for mouse primordial germ cell fate determination by ensuring BMP signaling

Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells

Structure‐Guided Discovery of a Potent and Selective Cell‐Active Inhibitor of SETDB1 Tudor Domain

Silencing of endogenous retroviruses by heterochromatin

SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation

Co-transcriptional genome surveillance by HUSH is coupled to termination machinery

SETDB1-Mediated Silencing of Retroelements

Transcription factor FOXM1 promotes hepatocellular carcinoma malignant progression through activation of the WNT pathway by binding to SETDB1

Roles of the histone methyltransferase SET domain bifurcated 1 in epithelial cells during tooth development

Transcriptome-wide Dynamics of m6A mRNA Methylation During Porcine Spermatogenesis

Mechanism of SUMOylation-Mediated Regulation of Type I IFN Expression

Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46

SETDB1, an H3K9-specific methyltransferase: An attractive epigenetic target to combat cancer

Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

Histone methyltransferase SETDB1 inhibits TGF-β-induced epithelial–mesenchymal transition in pulmonary fibrosis by regulating SNAI1 expression and the ferroptosis signaling pathway

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