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Screening of a small, well-curated natural product-based library identifies two rotenoids with potent nematocidal activity against Haemonchus contortus

Veterinary parasitology, 2017-09, Vol.244, p.172-175

2017

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Discovery of a simplified deguelin analog as an HSP90 C-terminal inhibitor for HER2-positive breast cancer

Bioorganic & medicinal chemistry letters, 2021-08, Vol.45, p.128134-128134, Article 128134

2021

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Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion

Oncotarget, 2018-05, Vol.9 (36), p.24199-24208

2018

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Multi-omics analysis unravels positive effect of rotenone on the cordycepin biosynthesis in submerged fermentation of Cordyceps militaris

Bioresource technology, 2023-04, Vol.373, p.128705-128705, Article 128705

2023

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Mitochondrial function influences expression of methamphetamine-induced behavioral sensitization

Scientific reports, 2021-12, Vol.11 (1), p.24529-15, Article 24529

2021

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Baicalein inhibits α-synuclein oligomer formation and prevents progression of α-synuclein accumulation in a rotenone mouse model of Parkinson's disease

Biochimica et biophysica acta, 2016-10, Vol.1862 (10), p.1883-1890

2016

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Metformin attenuates rotenone-induced oxidative stress and mitochondrial damage via the AKT/Nrf2 pathway

Neurochemistry international, 2021-09, Vol.148, p.105120-105120, Article 105120

2021

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Kolaviron protects against nigrostriatal degeneration and gut oxidative damage in a stereotaxic rotenone model of Parkinson’s disease

Psychopharmacology, 2020-11, Vol.237 (11), p.3225-3236

2020

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A strategy for the investigation of toxic mechanisms and protection by efflux pumps using Schizosaccharomyces pombe strains: Application to rotenone

The Science of the total environment, 2024-04, Vol.922, p.171253-171253, Article 171253

2024

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Design, Synthesis, and Biological Evaluation of Novel Deguelin-Based Heat Shock Protein 90 (HSP90) Inhibitors Targeting Proliferation and Angiogenesis

Journal of medicinal chemistry, 2012-12, Vol.55 (24), p.10863-10884

2012

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Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1370-1381

2019

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A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis

Archives of toxicology, 2016-11, Vol.90 (11), p.2725-2743

2016

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Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice

PloS one, 2010-01, Vol.5 (1), p.e8762-e8762

2010

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Antiviral Rotenoids and Isoflavones Isolated from Millettia oblata ssp. teitensis

Journal of natural products (Washington, D.C.), 2024-04, Vol.87 (4), p.1003-1012

2024

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Fecal microbiota transplantation protects rotenone-induced Parkinson's disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 signaling pathway through the microbiota-gut-brain axis

Microbiome, 2021-11, Vol.9 (1), p.226-226, Article 226

2021

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Protective capacity of carotenoid trans-astaxanthin in rotenone-induced toxicity in Drosophila melanogaster

Scientific reports, 2022-03, Vol.12 (1), p.4594-4594, Article 4594

2022

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Microglial Activation Damages Dopaminergic Neurons through MMP-2/-9-Mediated Increase of Blood-Brain Barrier Permeability in a Parkinson's Disease Mouse Model

International journal of molecular sciences, 2022-03, Vol.23 (5), p.2793

2022

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Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation

Nature genetics, 2021-03, Vol.53 (3), p.304-312

2021

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Rotenone impairs learning and memory in mice through microglia-mediated blood brain barrier disruption and neuronal apoptosis

Chemosphere (Oxford), 2022-03, Vol.291 (Pt 2), p.132982-132982, Article 132982

2022

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Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells

Cell reports (Cambridge), 2018-04, Vol.23 (1), p.58-67

2018

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N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data

PloS one, 2016-06, Vol.11 (6), p.e0157602

2016

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An endoplasmic reticulum-targeting fluorescent probe for the visualization of superoxide anion (O2•−) in living cells during ferroptosis

Microchemical journal, 2024-06, Vol.201, p.110570, Article 110570

2024

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Deguelin targets multiple oncogenic signaling pathways to combat human malignancies

Pharmacological research, 2021-04, Vol.166, p.105487-105487, Article 105487

2021

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Mitochondrial ATP-sensitive potassium channel regulates mitochondrial dynamics to participate in neurodegeneration of Parkinson's disease

Biochimica et biophysica acta. Molecular basis of disease, 2018-04, Vol.1864 (4), p.1086-1103

2018

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The molecular mechanism of rotenone-induced α-synuclein aggregation: Emphasizing the role of the calcium/GSK3β pathway

Toxicology letters, 2015-03, Vol.233 (2), p.163-171

2015

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Screening of a small, well-curated natural product-based library identifies two rotenoids with potent nematocidal activity against Haemonchus contortus

Discovery of a simplified deguelin analog as an HSP90 C-terminal inhibitor for HER2-positive breast cancer

Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion

Multi-omics analysis unravels positive effect of rotenone on the cordycepin biosynthesis in submerged fermentation of Cordyceps militaris

Mitochondrial function influences expression of methamphetamine-induced behavioral sensitization

Baicalein inhibits α-synuclein oligomer formation and prevents progression of α-synuclein accumulation in a rotenone mouse model of Parkinson's disease

Metformin attenuates rotenone-induced oxidative stress and mitochondrial damage via the AKT/Nrf2 pathway

Kolaviron protects against nigrostriatal degeneration and gut oxidative damage in a stereotaxic rotenone model of Parkinson’s disease

A strategy for the investigation of toxic mechanisms and protection by efflux pumps using Schizosaccharomyces pombe strains: Application to rotenone

Design, Synthesis, and Biological Evaluation of Novel Deguelin-Based Heat Shock Protein 90 (HSP90) Inhibitors Targeting Proliferation and Angiogenesis

Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents

A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis

Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice

Antiviral Rotenoids and Isoflavones Isolated from Millettia oblata ssp. teitensis

Fecal microbiota transplantation protects rotenone-induced Parkinson's disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 signaling pathway through the microbiota-gut-brain axis

Protective capacity of carotenoid trans-astaxanthin in rotenone-induced toxicity in Drosophila melanogaster

Microglial Activation Damages Dopaminergic Neurons through MMP-2/-9-Mediated Increase of Blood-Brain Barrier Permeability in a Parkinson's Disease Mouse Model

Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation

Rotenone impairs learning and memory in mice through microglia-mediated blood brain barrier disruption and neuronal apoptosis

Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells

N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data

An endoplasmic reticulum-targeting fluorescent probe for the visualization of superoxide anion (O2•−) in living cells during ferroptosis

Deguelin targets multiple oncogenic signaling pathways to combat human malignancies

Mitochondrial ATP-sensitive potassium channel regulates mitochondrial dynamics to participate in neurodegeneration of Parkinson's disease

The molecular mechanism of rotenone-induced α-synuclein aggregation: Emphasizing the role of the calcium/GSK3β pathway

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