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Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2219038-2219038

2023

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Ribosome Inactivating Toxins

2019

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Strong protection against ricin challenge induced by a novel modified ricin A-chain protein in mouse model

Human vaccines & immunotherapeutics, 2015-07, Vol.11 (7), p.1779-1787

2015

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A novel recombinant vaccine protecting mice against abrin intoxication

Human vaccines & immunotherapeutics, 2015-06, Vol.11 (6), p.1361-1367

2015

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Ricin A chain utilises the endoplasmic reticulum-associated protein degradation pathway to enter the cytosol of yeast

FEBS letters, 1999-10, Vol.459 (1), p.80-84

1999

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Ricin toxin and its neutralizing antibodies: A review

Toxicon (Oxford), 2022-07, Vol.214, p.47-53

2022

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Anti-ricin toxin human neutralizing antibodies and DMAbs protection against ricin toxin poisoning

Toxicology letters, 2023-07, Vol.383, p.152-161

2023

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One problem, multiple potential targets: Where are we now in the development of small molecule inhibitors against Shiga toxin?

Cellular signalling, 2024-09, Vol.121, p.111253, Article 111253

2024

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Analysis of the microRNA and mRNA expression profile of ricin toxin-treated RAW264.7 cells reveals that miR-155-3p suppresses cell inflammation by targeting GAB2

Toxicology letters, 2021-09, Vol.347, p.67-77

2021

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A novel circular RNA circNLRP3 alleviated ricin toxin-induced TNF-α production through sponging miR-221–5p

Toxicon (Oxford), 2023-03, Vol.224, p.107046, Article 107046

2023

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Caspase-3/Gasdermin E-mediated pyroptosis contributes to Ricin toxin-induced inflammation

Toxicology letters, 2024-05, Vol.396, p.19-27

2024

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MicroRNA-221-5p Promotes Ricin Toxin-induced Inflammation via PI3K/Akt signaling pathway by targeting COL4a5

Toxicon (Oxford), 2022-06, Vol.212, p.11-18

2022

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A novel EGFR-specific recombinant ricin-panitumumab (scFv) immunotoxin against breast and colorectal cancer cell lines; in silico and in vitro analyses

European journal of pharmacology, 2023-09, Vol.955, p.175894-175894, Article 175894

2023

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Autophagic Degradation Is Involved in Cell Protection against Ricin Toxin

Toxins, 2023-04, Vol.15 (5), p.304

2023

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Estimating Vaccine Potency Using Antibody-Based Competition Assays

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2410, p.693

2022

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Crystal structure of Mycobacterium tuberculosis VapC20 toxin and its interactions with cognate antitoxin, VapB20, suggest a model for toxin–antitoxin assembly

The FEBS journal, 2017-12, Vol.284 (23), p.4066-4082

2017

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Programmable hybridization assemble nicked displacement amplification for detecting ricin toxin

Sensors and actuators. B, Chemical, 2022-10, Vol.368, p.132139, Article 132139

2022

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Necroptosis of Lung Epithelial Cells Triggered by Ricin Toxin and Bystander Inflammation

Cellular physiology and biochemistry, 2023-01, Vol.57 (1), p.1-14

2023

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CircEpc1 Promotes Ricin Toxin-Induced Inflammation via Activation of NF-κB and MAPK Signaling Pathways by Sponging miR-5114

Frontiers in pharmacology, 2021-10, Vol.12, p.767900-767900

2021

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Identification of a lncRNA/circRNA-miRNA-mRNA network to explore the effects of ricin toxin-induced inflammation in RAW264.7 cells

Toxicon (Oxford), 2021-11, Vol.203, p.129-138

2021

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Pretreatment with Retro‐2 protects cells from death caused by ricin toxin by retaining the capacity of protein synthesis

Journal of applied toxicology, 2020-10, Vol.40 (10), p.1440-1450

2020

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Critical role of toll-like receptor 4 (TLR4) in ricin toxin-induced inflammatory responses in macrophages

Toxicology letters, 2020-03, Vol.321, p.54-60

2020

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An in vitro evaluation of epigallocatechin gallate (eGCG) as a biocompatible inhibitor of ricin toxin

Biochimica et biophysica acta, 2016-07, Vol.1860 (7), p.1541-1550

2016

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Development of a highly sensitive in vitro endothelial cell toxicity assay for evaluating ricin toxin A chain-based vaccines or therapeutics

Toxicon (Oxford), 2019-09, Vol.167, p.152-161

2019

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Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor

Ribosome Inactivating Toxins

Strong protection against ricin challenge induced by a novel modified ricin A-chain protein in mouse model

A novel recombinant vaccine protecting mice against abrin intoxication

Ricin A chain utilises the endoplasmic reticulum-associated protein degradation pathway to enter the cytosol of yeast

Ricin toxin and its neutralizing antibodies: A review

Anti-ricin toxin human neutralizing antibodies and DMAbs protection against ricin toxin poisoning

One problem, multiple potential targets: Where are we now in the development of small molecule inhibitors against Shiga toxin?

Analysis of the microRNA and mRNA expression profile of ricin toxin-treated RAW264.7 cells reveals that miR-155-3p suppresses cell inflammation by targeting GAB2

A novel circular RNA circNLRP3 alleviated ricin toxin-induced TNF-α production through sponging miR-221–5p

Caspase-3/Gasdermin E-mediated pyroptosis contributes to Ricin toxin-induced inflammation

MicroRNA-221-5p Promotes Ricin Toxin-induced Inflammation via PI3K/Akt signaling pathway by targeting COL4a5

A novel EGFR-specific recombinant ricin-panitumumab (scFv) immunotoxin against breast and colorectal cancer cell lines; in silico and in vitro analyses

Autophagic Degradation Is Involved in Cell Protection against Ricin Toxin

Estimating Vaccine Potency Using Antibody-Based Competition Assays

Crystal structure of Mycobacterium tuberculosis VapC20 toxin and its interactions with cognate antitoxin, VapB20, suggest a model for toxin–antitoxin assembly

Programmable hybridization assemble nicked displacement amplification for detecting ricin toxin

Necroptosis of Lung Epithelial Cells Triggered by Ricin Toxin and Bystander Inflammation

CircEpc1 Promotes Ricin Toxin-Induced Inflammation via Activation of NF-κB and MAPK Signaling Pathways by Sponging miR-5114

Identification of a lncRNA/circRNA-miRNA-mRNA network to explore the effects of ricin toxin-induced inflammation in RAW264.7 cells

Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales

Pretreatment with Retro‐2 protects cells from death caused by ricin toxin by retaining the capacity of protein synthesis

Critical role of toll-like receptor 4 (TLR4) in ricin toxin-induced inflammatory responses in macrophages

An in vitro evaluation of epigallocatechin gallate (eGCG) as a biocompatible inhibitor of ricin toxin

Development of a highly sensitive in vitro endothelial cell toxicity assay for evaluating ricin toxin A chain-based vaccines or therapeutics

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