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Biased Opioid Ligands

Molecules (Basel, Switzerland), 2020-09, Vol.25 (18), p.4257

2020

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Delta Opioid Receptors and Modulation of Mood and Emotion

Delta Opioid Receptor Pharmacology and Therapeutic Applications, 2018, Vol.247, p.179-197

2018

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Molecular control of δ-opioid receptor signalling

Nature (London), 2014-02, Vol.506 (7487), p.191-196

2014

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Novel Molecular Targets of Dezocine and Their Clinical Implications

Anesthesiology (Philadelphia), 2014-03, Vol.120 (3), p.714-723

2014

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The selective non-peptidic delta opioid agonist SNC80 does not facilitate intracranial self-stimulation in rats

European journal of pharmacology, 2009-02, Vol.604 (1), p.58-65

2009

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Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain

Cell, 2009-06, Vol.137 (6), p.1148-1159

2009

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Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (26), p.15281-15292

2020

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Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, inflammatory and neuropathic pain, respiration, and drug self-administration

Psychopharmacology, 2020-04, Vol.237 (4), p.1195-1208

2020

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Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications

Future medicinal chemistry, 2014-03, Vol.6 (4), p.385-412

2014

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Signaling diversity of mu- and delta- opioid receptor ligands: Re-evaluating the benefits of β-arrestin/G protein signaling bias

Cellular signalling, 2021-04, Vol.80, p.109906-109906, Article 109906

2021

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Positive allosteric modulation of endogenous delta opioid receptor signaling in the enteric nervous system is a potential treatment for gastrointestinal motility disorders

American journal of physiology: Gastrointestinal and liver physiology, 2022-01, Vol.322 (1), p.G66-G78

2022

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Molecular Pharmacology of δ-Opioid Receptors

Pharmacological reviews, 2016-07, Vol.68 (3), p.631-700

2016

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Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.1612-1661

2022

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Opioids differentially modulate two synapses important for pain processing in the amygdala

British journal of pharmacology, 2020-01, Vol.177 (2), p.420-431

2020

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Synapse-specific opioid modulation of thalamo-cortico-striatal circuits

eLife, 2019-05, Vol.8

2019

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Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (29), p.12072-12077

2013

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Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal

Cellular and molecular neurobiology, 2021-07, Vol.41 (5), p.1131-1143

2021

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The Delta-Opioid Receptor Bidirectionally Modulates Itch

The journal of pain, 2023-02, Vol.24 (2), p.264-272

2023

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Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3

Neoplasia (New York, N.Y.), 2021-02, Vol.23 (2), p.270-279

2021

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Two delta opioid receptor subtypes are functional in single ventral tegmental area neurons, and can interact with the mu opioid receptor

Neuropharmacology, 2017-09, Vol.123, p.420-432

2017

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Changes in opioid receptors, opioid peptides and morphine antinociception in mice subjected to early life stress

European journal of pharmacology, 2020-08, Vol.881, p.173173-173173, Article 173173

2020

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Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure–Activity Relationship Studies

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12929-12941

2020

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Expression and Localization of Opioid Receptors in Male Germ Cells and the Implication for Mouse Spermatogenesis

PloS one, 2016-03, Vol.11 (3), p.e0152162-e0152162

2016

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Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists

Molecules (Basel, Switzerland), 2021-11, Vol.26 (21), p.6693

2021

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Agonist-induced phosphorylation bar code and differential post-activation signaling of the delta opioid receptor revealed by phosphosite-specific antibodies

Scientific reports, 2020-05, Vol.10 (1), p.8585-20, Article 8585

2020

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Biased Opioid Ligands

Delta Opioid Receptors and Modulation of Mood and Emotion

Molecular control of δ-opioid receptor signalling

Novel Molecular Targets of Dezocine and Their Clinical Implications

The selective non-peptidic delta opioid agonist SNC80 does not facilitate intracranial self-stimulation in rats

Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain

Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain

Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, inflammatory and neuropathic pain, respiration, and drug self-administration

Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications

Signaling diversity of mu- and delta- opioid receptor ligands: Re-evaluating the benefits of β-arrestin/G protein signaling bias

Positive allosteric modulation of endogenous delta opioid receptor signaling in the enteric nervous system is a potential treatment for gastrointestinal motility disorders

Molecular Pharmacology of δ-Opioid Receptors

Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources

Opioids differentially modulate two synapses important for pain processing in the amygdala

Synapse-specific opioid modulation of thalamo-cortico-striatal circuits

Identification of a μ-δ opioid receptor heteromer-biased agonist with antinociceptive activity

Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal

The Delta-Opioid Receptor Bidirectionally Modulates Itch

Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3

Two delta opioid receptor subtypes are functional in single ventral tegmental area neurons, and can interact with the mu opioid receptor

Changes in opioid receptors, opioid peptides and morphine antinociception in mice subjected to early life stress

Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure–Activity Relationship Studies

Expression and Localization of Opioid Receptors in Male Germ Cells and the Implication for Mouse Spermatogenesis

Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists

Agonist-induced phosphorylation bar code and differential post-activation signaling of the delta opioid receptor revealed by phosphosite-specific antibodies

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