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Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans

Nature communications, 2015-11, Vol.6 (1), p.8951, Article 8951

2015

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Lipoprotein(a) Levels in Familial Hypercholesterolemia: An Important Predictor of Cardiovascular Disease Independent of the Type of LDL Receptor Mutation

Journal of the American College of Cardiology, 2014-05, Vol.63 (19), p.1982-1989

2014

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Cyclase-associated protein 1 is a binding partner of proprotein convertase subtilisin/kexin type-9 and is required for the degradation of low-density lipoprotein receptors by proprotein convertase subtilisin/kexin type-9

European heart journal, 2020-01, Vol.41 (2), p.239-252

2020

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LR11/SorLA links triglyceride-rich lipoproteins to risk of developing cardiovascular disease in FH patients

Atherosclerosis, 2015-12, Vol.243 (2), p.429-437

2015

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Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants in Patient Lymphocytes to Assess the Effect of Evinacumab in Homozygous Familial Hypercholesterolemia Patients With a Spectrum of LDLR Activity

Arteriosclerosis, thrombosis, and vascular biology, 2019-11, Vol.39 (11), p.2248-2260

2019

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Serum Proprotein Convertase Subtilisin/Kexin Type 9 and Cell Surface Low-Density Lipoprotein Receptor: Evidence for a Reciprocal Regulation

Circulation (New York, N.Y.), 2013-06, Vol.127 (24), p.2403-2413

2013

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The Severe Hypercholesterolemia Phenotype: Clinical Diagnosis, Management, and Emerging Therapies

Journal of the American College of Cardiology, 2014-05, Vol.63 (19), p.1935-1947

2014

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Serum low-density lipoprotein and low-density lipoprotein expression level at diagnosis are favorable prognostic factors in patients with small-cell lung cancer (SCLC)

BMC cancer, 2017-04, Vol.17 (1), p.269-269, Article 269

2017

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Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research

Arteriosclerosis, thrombosis, and vascular biology, 2018-09, Vol.38 (9), p.1997-2006

2018

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Circulating soluble LR11, a novel marker of smooth muscle cell proliferation, is enhanced after coronary stenting in response to vascular injury

Atherosclerosis, 2014-11, Vol.237 (1), p.374-378

2014

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Pharmacological aspects of ANGPTL3 and ANGPTL4 inhibitors: New therapeutic approaches for the treatment of atherogenic dyslipidemia

Pharmacological research, 2020-03, Vol.153, p.104653, Article 104653

2020

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Hepatic Sensing Loop Regulates PCSK9 Secretion in Response to Inhibitory Antibodies

Journal of the American College of Cardiology, 2021-10, Vol.78 (14), p.1437-1449

2021

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On the function and homeostasis of PCSK9: Reciprocal interaction with LDLR and additional lipid effects

Atherosclerosis, 2015-02, Vol.238 (2), p.264-270

2015

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Divergent low-density lipoprotein receptor (LDLR) linked to low VSV G-dependent viral infectivity and unique serum lipid profile in zebra finches

Proceedings of the National Academy of Sciences - PNAS, 2021-05, Vol.118 (18), p.1-3

2021

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Sorting an LDL receptor with bound PCSK9 to intracellular degradation

Atherosclerosis, 2014-11, Vol.237 (1), p.76-81

Leren, Trond P

2014

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Inflammation stimulates the expression of PCSK9

Biochemical and biophysical research communications, 2008-09, Vol.374 (2), p.341-344

2008

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Subendothelial retention of atherogenic lipoproteins in early atherosclerosis

Nature (London), 2002-06, Vol.417 (6890), p.750-754

2002

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Genetic Architecture of Familial Hypercholesterolaemia

Current cardiology reports, 2017-05, Vol.19 (5), p.44-44, Article 44

2017

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Mechanisms by which Dietary Fatty Acids Modulate Plasma Lipids

The Journal of nutrition, 2005-09, Vol.135 (9), p.2075-2078

2005

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The Central Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Septic Pathogen Lipid Transport and Clearance

American journal of respiratory and critical care medicine, 2015-12, Vol.192 (11), p.1275-1286

2015

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IDOL G51S Variant Is Associated With High Blood Cholesterol and Increases Low-Density Lipoprotein Receptor Degradation

Arteriosclerosis, thrombosis, and vascular biology, 2019-12, Vol.39 (12), p.2468-2479

2019

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Associations Between Soluble LDLR and Lipoproteins in a White Cohort and the Effect of PCSK9 Loss-of-Function

The journal of clinical endocrinology and metabolism, 2018-09, Vol.103 (9), p.3486-3495

2018

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Improved cardiovascular outcomes following temporal advances in lipid-lowering therapy in a genetically-characterised cohort of familial hypercholesterolaemia homozygotes

Atherosclerosis, 2015-11, Vol.243 (1), p.328-333

2015

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Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling

Molecular and cellular biology, 2016-10, Vol.36 (20), p.2645-2654

2016

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Performance comparison of different classification algorithms applied to the diagnosis of familial hypercholesterolemia in paediatric subjects

Scientific reports, 2022-01, Vol.12 (1), p.1164-1164, Article 1164

2022

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Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans

Lipoprotein(a) Levels in Familial Hypercholesterolemia: An Important Predictor of Cardiovascular Disease Independent of the Type of LDL Receptor Mutation

Cyclase-associated protein 1 is a binding partner of proprotein convertase subtilisin/kexin type-9 and is required for the degradation of low-density lipoprotein receptors by proprotein convertase subtilisin/kexin type-9

LR11/SorLA links triglyceride-rich lipoproteins to risk of developing cardiovascular disease in FH patients

Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants in Patient Lymphocytes to Assess the Effect of Evinacumab in Homozygous Familial Hypercholesterolemia Patients With a Spectrum of LDLR Activity

Serum Proprotein Convertase Subtilisin/Kexin Type 9 and Cell Surface Low-Density Lipoprotein Receptor: Evidence for a Reciprocal Regulation

The Severe Hypercholesterolemia Phenotype: Clinical Diagnosis, Management, and Emerging Therapies

Serum low-density lipoprotein and low-density lipoprotein expression level at diagnosis are favorable prognostic factors in patients with small-cell lung cancer (SCLC)

Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research

Circulating soluble LR11, a novel marker of smooth muscle cell proliferation, is enhanced after coronary stenting in response to vascular injury

Pharmacological aspects of ANGPTL3 and ANGPTL4 inhibitors: New therapeutic approaches for the treatment of atherogenic dyslipidemia

Hepatic Sensing Loop Regulates PCSK9 Secretion in Response to Inhibitory Antibodies

On the function and homeostasis of PCSK9: Reciprocal interaction with LDLR and additional lipid effects

Divergent low-density lipoprotein receptor (LDLR) linked to low VSV G-dependent viral infectivity and unique serum lipid profile in zebra finches

Sorting an LDL receptor with bound PCSK9 to intracellular degradation

Inflammation stimulates the expression of PCSK9

Subendothelial retention of atherogenic lipoproteins in early atherosclerosis

Genetic Architecture of Familial Hypercholesterolaemia

Mechanisms by which Dietary Fatty Acids Modulate Plasma Lipids

The Central Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Septic Pathogen Lipid Transport and Clearance

IDOL G51S Variant Is Associated With High Blood Cholesterol and Increases Low-Density Lipoprotein Receptor Degradation

Associations Between Soluble LDLR and Lipoproteins in a White Cohort and the Effect of PCSK9 Loss-of-Function

Improved cardiovascular outcomes following temporal advances in lipid-lowering therapy in a genetically-characterised cohort of familial hypercholesterolaemia homozygotes

Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling

Performance comparison of different classification algorithms applied to the diagnosis of familial hypercholesterolemia in paediatric subjects

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