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Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation

Frontiers in immunology, 2019-05, Vol.10, p.1179

2019

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HIV―1 adaptation to NK―cell―mediated immune pressure

Nature (London), 2011-08, Vol.476 (7358), p.96-100

2011

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MHC class I–specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

Blood, 2008-09, Vol.112 (6), p.2369-2380

2008

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Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition

Annual review of immunology, 2013-01, Vol.31 (1), p.227-258

2013

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Preclinical characterization of 1-7F9, a novel human anti–KIR receptor therapeutic antibody that augments natural killer–mediated killing of tumor cells

Blood, 2009-09, Vol.114 (13), p.2667-2677

2009

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Co-evolution of MHC class I and variable NK cell receptors in placental mammals

Immunological reviews, 2015-09, Vol.267 (1), p.259-282

2015

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Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations

Immunology, 2011-03, Vol.132 (3), p.315-325

2011

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Pre-eclampsia: Re-visiting pathophysiology, role of immune cells, biomarker identification and recent advances in its management

Journal of reproductive immunology, 2024-06, Vol.163, p.104236, Article 104236

2024

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Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors

The Journal of immunology (1950), 2013-04, Vol.190 (8), p.3939-3948

2013

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NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs

Blood, 2013-04, Vol.121 (14), p.2678-2688

2013

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Underrepresentation of activating KIR gene expression in single‐cell RNA‐seq data is due to KIR gene misassignment

European journal of immunology, 2024-01, Vol.54 (1), p.e2350590-n/a

2024

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Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function

Blood, 2012-03, Vol.119 (11), p.2665-2674

2012

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Co-evolution of NK receptors and HLA ligands in humans is driven by reproduction

Immunological reviews, 2015-09, Vol.267 (1), p.283-297

2015

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Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

Nature communications, 2020-01, Vol.11 (1), p.381-381, Article 381

2020

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Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients

Clinical immunology (Orlando, Fla.), 2020-06, Vol.215, p.108410-108410, Article 108410

2020

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Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

Blood, 2009-03, Vol.113 (13), p.3119-3129

2009

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extensive polymorphism of KIR genes

Immunology, 2010-01, Vol.129 (1), p.8-19

2010

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Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells

The Journal of immunology (1950), 2015-03, Vol.194 (6), p.2467-2471

2015

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Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

Nature communications, 2019-03, Vol.10 (1), p.1065-1065, Article 1065

2019

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Increased donor inhibitory KIR are associated with reduced GVHD and improved survival following HLA‐matched unrelated donor HCT in paediatric acute leukaemia

British journal of haematology, 2024-05, Vol.204 (5), p.1935-1943

2024

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Natural Killer Cell Education and the Response to Infection and Cancer Therapy: Stay Tuned

Trends in immunology, 2018-03, Vol.39 (3), p.222-239

2018

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Uterine natural killer cells: from foe to friend in reproduction

Human reproduction update, 2021-06, Vol.27 (4), p.720-746

2021

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Maternal KIR in combination with paternal HLA-C2 regulate human birth weight

The Journal of immunology (1950), 2014-06, Vol.192 (11), p.5069-5073

2014

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Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (26), p.12964-12973

2019

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Cord blood stem cell-generated KIR+NK cells effectively target leukemia cell lines

Human immunology, 2023-02, Vol.84 (2), p.98-105

2023

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Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation

HIV―1 adaptation to NK―cell―mediated immune pressure

MHC class I–specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition

Preclinical characterization of 1-7F9, a novel human anti–KIR receptor therapeutic antibody that augments natural killer–mediated killing of tumor cells

Co-evolution of MHC class I and variable NK cell receptors in placental mammals

Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations

Pre-eclampsia: Re-visiting pathophysiology, role of immune cells, biomarker identification and recent advances in its management

Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors

NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs

Underrepresentation of activating KIR gene expression in single‐cell RNA‐seq data is due to KIR gene misassignment

Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function

Co-evolution of NK receptors and HLA ligands in humans is driven by reproduction

Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

extensive polymorphism of KIR genes

Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells

Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

Increased donor inhibitory KIR are associated with reduced GVHD and improved survival following HLA‐matched unrelated donor HCT in paediatric acute leukaemia

Natural Killer Cell Education and the Response to Infection and Cancer Therapy: Stay Tuned

Uterine natural killer cells: from foe to friend in reproduction

Maternal KIR in combination with paternal HLA-C2 regulate human birth weight

Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C

Cord blood stem cell-generated KIR+NK cells effectively target leukemia cell lines

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