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FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABA B Receptor

Cell chemical biology, 2017-03, Vol.24 (3), p.360-370

2017

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Exploring the Binding Mechanism of GABA B Receptor Agonists and Antagonists through in Silico Simulations

Journal of chemical information and modeling, 2020-02, Vol.60 (2), p.1005-1018

2020

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Structural basis of the activation of a metabotropic GABA receptor

Nature (London), 2020-08, Vol.584 (7820), p.298-303

2020

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Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen

Science translational medicine, 2012-09, Vol.4 (152), p.152ra128

2012

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Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue

Cell, 2019-05, Vol.177 (5), p.1280-1292.e20

2019

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Structures of metabotropic GABA B receptor

Nature (London), 2020-08, Vol.584 (7820), p.310

2020

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Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives

Pharmacological reviews, 2011-03, Vol.63 (1), p.59-126

2011

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Organization and functions of mGlu and GABA B receptor complexes

Nature (London), 2016-12, Vol.540 (7631), p.60

2016

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GABA-receptive microglia selectively sculpt developing inhibitory circuits

Cell, 2021-07, Vol.184 (15), p.4048-4063.e32

2021

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GABA B receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles

Proceedings of the National Academy of Sciences - PNAS, 2024-02, Vol.121 (8), p.e2301449121

2024

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α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA B receptors

Gut, 2017-06, Vol.66 (6), p.1083-1094

2017

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Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression

Nature cell biology, 2022-02, Vol.24 (2), p.230-241

2022

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Prefrontal cortical GABAergic dysfunction contributes to age-related working memory impairment

The Journal of neuroscience, 2014-03, Vol.34 (10), p.3457-3466

2014

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Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer

Nature chemical biology, 2015-02, Vol.11 (2), p.134-140

2015

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Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen

Lancet neurology, 2010-01, Vol.9 (1), p.67-76

2010

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Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits

Nature (London), 2010-05, Vol.465 (7295), p.231-235

2010

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Complex formation of APP with GABA B receptors links axonal trafficking to amyloidogenic processing

Nature communications, 2019-12, Vol.10 (1), p.1331

2019

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Role of GABA(B) receptors in learning and memory and neurological disorders

Neuroscience and biobehavioral reviews, 2016-04, Vol.63, p.1-28

2016

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GABAB receptor modulation of synaptic function

Current opinion in neurobiology, 2011-04, Vol.21 (2), p.339-344

2011

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GABA Receptors: Pharmacological Potential and Pitfalls

Current pharmaceutical design, 2015-01, Vol.21 (34), p.4943-4959

2015

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Asymmetric activation of dimeric GABA B and metabotropic glutamate receptors

American Journal of Physiology: Cell Physiology, 2023-07, Vol.325 (1), p.C79-C89

2023

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Distinct mechanisms of CB1 and GABA B receptor presynaptic modulation of striatal indirect pathway projections to mouse globus pallidus

The Journal of physiology, 2023-01, Vol.601 (1), p.195-209

2023

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Inhibition of Nigrostriatal Dopamine Release by Striatal GABA A and GABA B Receptors

The Journal of neuroscience, 2019-02, Vol.39 (6), p.1058-1065

2019

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Amorphous solid dispersion successfully improved oral exposure of ADX71943 in support of toxicology studies

Drug development and industrial pharmacy, 2013-09, Vol.39 (9), p.1300-1305

2013

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KCTD Hetero-oligomers Confer Unique Kinetic Properties on Hippocampal GABAB Receptor-Induced K+ Currents

The Journal of neuroscience, 2017-02, Vol.37 (5), p.1162-1175

2017

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FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABA B Receptor

Exploring the Binding Mechanism of GABA B Receptor Agonists and Antagonists through in Silico Simulations

Structural basis of the activation of a metabotropic GABA receptor

Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen

Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue

Structures of metabotropic GABA B receptor

Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives

Organization and functions of mGlu and GABA B receptor complexes

GABA-receptive microglia selectively sculpt developing inhibitory circuits

GABA B receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles

α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA B receptors

Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression

Prefrontal cortical GABAergic dysfunction contributes to age-related working memory impairment

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer

Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen

Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits

Complex formation of APP with GABA B receptors links axonal trafficking to amyloidogenic processing

Role of GABA(B) receptors in learning and memory and neurological disorders

GABAB receptor modulation of synaptic function

GABA Receptors: Pharmacological Potential and Pitfalls

Asymmetric activation of dimeric GABA B and metabotropic glutamate receptors

Distinct mechanisms of CB1 and GABA B receptor presynaptic modulation of striatal indirect pathway projections to mouse globus pallidus

Inhibition of Nigrostriatal Dopamine Release by Striatal GABA A and GABA B Receptors

Amorphous solid dispersion successfully improved oral exposure of ADX71943 in support of toxicology studies

KCTD Hetero-oligomers Confer Unique Kinetic Properties on Hippocampal GABAB Receptor-Induced K+ Currents

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