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Lamin B Receptor Recognizes Specific Modifications of Histone H4 in Heterochromatin Formation

The Journal of biological chemistry, 2012-12, Vol.287 (51), p.42654-42663

2012

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REV-ERB and ROR nuclear receptors as drug targets

Nature reviews. Drug discovery, 2014-03, Vol.13 (3), p.197-216

2014

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Nuclear Receptors, RXR, and the Big Bang

Cell, 2014-03, Vol.157 (1), p.255-266

2014

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Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

Nature (London), 2015-06, Vol.522 (7556), p.359-362

2015

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Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation

Cell, 2016-08, Vol.166 (5), p.1084-1102

2016

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Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains

Cell, 2018-04, Vol.173 (3), p.677-692.e20

2018

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D3R Grand Challenge 2: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies

Journal of computer-aided molecular design, 2018-01, Vol.32 (1), p.1-20

2018

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Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival

Developmental cell, 2017-04, Vol.41 (1), p.33-46.e7

2017

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Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor

Journal of medicinal chemistry, 2021-12, Vol.64 (24), p.17545-17571

2021

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Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics

Annual review of physiology, 2010-01, Vol.72 (1), p.247-272

2010

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Privileged scaffolds for library design and drug discovery

Current opinion in chemical biology, 2010-06, Vol.14 (3), p.347-361

2010

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Molecular tuning of farnesoid X receptor partial agonism

Nature communications, 2019-07, Vol.10 (1), p.2915-14, Article 2915

2019

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Molecular determinants of drug–receptor binding kinetics

Drug discovery today, 2013-07, Vol.18 (13-14), p.667-673

2013

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The Orphan Nuclear Receptors Steroidogenic Factor-1 and Liver Receptor Homolog-1: Structure, Regulation, and Essential Roles in Mammalian Reproduction

Physiological reviews, 2019-04, Vol.99 (2), p.1249-1279

2019

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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate

Cell, 2020-07, Vol.182 (2), p.297-316.e27

2020

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Dissecting the molecular organization of the translocon-associated protein complex

Nature communications, 2017-02, Vol.8 (1), p.14516-14516, Article 14516

2017

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Structure and Regulation of Soluble Guanylate Cyclase

Annual review of biochemistry, 2012-01, Vol.81 (1), p.533-559

2012

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International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands

Pharmacological reviews, 2014-10, Vol.66 (4), p.918-947

2014

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Targeting Nuclear Receptors with PROTAC degraders

Molecular and cellular endocrinology, 2019-08, Vol.493, p.110452-110452, Article 110452

2019

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Performance of HADDOCK and a simple contact-based protein–ligand binding affinity predictor in the D3R Grand Challenge 2

Journal of computer-aided molecular design, 2018-01, Vol.32 (1), p.175-185

2018

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Novel mechanisms for DHEA action

Journal of molecular endocrinology, 2016-04, Vol.56 (3), p.R139-R155

2016

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Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding

The Journal of biological chemistry, 2018-11, Vol.293 (47), p.18180-18191

2018

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Atomic basis of CRM1-cargo recognition, release and inhibition

Seminars in cancer biology, 2014-08, Vol.27, p.52-61

2014

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Structure of the MeCP2–TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (16), p.E3243-E3250

2017

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Structure of a prehandover mammalian ribosomal SRP·SRP receptor targeting complex

Science (American Association for the Advancement of Science), 2018-04, Vol.360 (6386), p.323-327

2018

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Lamin B Receptor Recognizes Specific Modifications of Histone H4 in Heterochromatin Formation

REV-ERB and ROR nuclear receptors as drug targets

Nuclear Receptors, RXR, and the Big Bang

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation

Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains

D3R Grand Challenge 2: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies

Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival

Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor

Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics

Privileged scaffolds for library design and drug discovery

Molecular tuning of farnesoid X receptor partial agonism

Molecular determinants of drug–receptor binding kinetics

The Orphan Nuclear Receptors Steroidogenic Factor-1 and Liver Receptor Homolog-1: Structure, Regulation, and Essential Roles in Mammalian Reproduction

TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate

Dissecting the molecular organization of the translocon-associated protein complex

Structure and Regulation of Soluble Guanylate Cyclase

International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands

Targeting Nuclear Receptors with PROTAC degraders

Performance of HADDOCK and a simple contact-based protein–ligand binding affinity predictor in the D3R Grand Challenge 2

Novel mechanisms for DHEA action

Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding

Atomic basis of CRM1-cargo recognition, release and inhibition

Structure of the MeCP2–TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders

Structure of a prehandover mammalian ribosomal SRP·SRP receptor targeting complex

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