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The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications

Pharmacological reviews, 2011-09, Vol.63 (3), p.461-470

2011

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The therapeutic role of cannabinoid receptors and its agonists or antagonists in Parkinson's disease

Progress in neuro-psychopharmacology & biological psychiatry, 2020-01, Vol.96, p.109745, Article 109745

2020

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Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis

Molecules (Basel, Switzerland), 2018-08, Vol.23 (9), p.2183

2018

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RAMP and MRAP accessory proteins have selective effects on expression and signalling of the CB 1 , CB 2 , GPR18 and GPR55 cannabinoid receptors

British journal of pharmacology, 2024-07, Vol.181 (14), p.2212-2231

2024

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Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of sex-related differences

Experimental neurology, 2023-01, Vol.359, p.114232, Article 114232

2023

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Focus on cannabinoids and synthetic cannabinoids

Clinical pharmacology and therapeutics, 2017-02, Vol.101 (2), p.220-229

2017

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Comparative assessment of CacyBP/SIP, β‐catenin and cannabinoid receptors in the adrenals of hypertensive rats

Journal of cellular and molecular medicine, 2024-05, Vol.28 (10), p.e18376-n/a

2024

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Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets

Biochemical pharmacology, 2017-03, Vol.128, p.1-11

2017

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Why do cannabinoid receptors have more than one endogenous ligand?

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2012-12, Vol.367 (1607), p.3216-3228

2012

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Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex

Cell, 2019-01, Vol.176 (3), p.448-458.e12

2019

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Crystal Structure of the Human Cannabinoid Receptor CB2

Cell, 2019-01, Vol.176 (3), p.459-467.e13

2019

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7‑Alkyl-3-benzylcoumarins: A Versatile Scaffold for the Development of Potent and Selective Cannabinoid Receptor Agonists and Antagonists

Journal of medicinal chemistry, 2012-09, Vol.55 (18), p.7967-7977

2012

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WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway

Neuropharmacology, 2012-09, Vol.63 (4), p.653-666

2012

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Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development

PloS one, 2016-12, Vol.11 (12), p.e0167240

2016

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Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

Neuropharmacology, 2014-12, Vol.87, p.214-221

2014

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A GPR18‐based signalling system regulates IOP in murine eye

British journal of pharmacology, 2013-06, Vol.169 (4), p.834-843

2013

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Novel Cannabinoid Receptor 2 (CB2) Low Lipophilicity Agonists Produce Distinct cAMP and Arrestin Signalling Kinetics without Bias

International journal of molecular sciences, 2023-03, Vol.24 (7), p.6406

2023

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A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice

Neuropharmacology, 2013-08, Vol.71 (100), p.255-263

2013

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CB2 Cannabinoid Receptor as a Potential Target in Myocardial Infarction: Exploration of Molecular Pathogenesis and Therapeutic Strategies

International journal of molecular sciences, 2024-02, Vol.25 (3), p.1683

2024

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Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation

Histochemistry and cell biology, 2019-01, Vol.151 (1), p.5-20

2019

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Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ(9)-THC: mechanism underlying greater toxicity?

Life sciences (1973), 2014-02, Vol.97 (1), p.45

2014

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Neurobiological Interactions Between Stress and the Endocannabinoid System

Neuropsychopharmacology (New York, N.Y.), 2016-01, Vol.41 (1), p.80-102

2016

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Localization of diacylglycerol lipase-alpha around postsynaptic spine suggests close proximity between production site of an endocannabinoid, 2-arachidonoyl-glycerol, and presynaptic cannabinoid CB1 receptor

The Journal of neuroscience, 2006-05, Vol.26 (18), p.4740-4751

2006

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Progress in brain cannabinoid CB 2 receptor research: From genes to behavior

Neuroscience and biobehavioral reviews, 2019-03, Vol.98, p.208

2019

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Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina

International journal of molecular sciences, 2023-11, Vol.24 (21), p.15689

2023

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The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications

The therapeutic role of cannabinoid receptors and its agonists or antagonists in Parkinson's disease

Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis

RAMP and MRAP accessory proteins have selective effects on expression and signalling of the CB 1 , CB 2 , GPR18 and GPR55 cannabinoid receptors

Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of sex-related differences

Focus on cannabinoids and synthetic cannabinoids

Comparative assessment of CacyBP/SIP, β‐catenin and cannabinoid receptors in the adrenals of hypertensive rats

Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets

Why do cannabinoid receptors have more than one endogenous ligand?

Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex

Crystal Structure of the Human Cannabinoid Receptor CB2

7‑Alkyl-3-benzylcoumarins: A Versatile Scaffold for the Development of Potent and Selective Cannabinoid Receptor Agonists and Antagonists

WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway

Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development

Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

A GPR18‐based signalling system regulates IOP in murine eye

Novel Cannabinoid Receptor 2 (CB2) Low Lipophilicity Agonists Produce Distinct cAMP and Arrestin Signalling Kinetics without Bias

A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice

CB2 Cannabinoid Receptor as a Potential Target in Myocardial Infarction: Exploration of Molecular Pathogenesis and Therapeutic Strategies

Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation

Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ(9)-THC: mechanism underlying greater toxicity?

Neurobiological Interactions Between Stress and the Endocannabinoid System

Localization of diacylglycerol lipase-alpha around postsynaptic spine suggests close proximity between production site of an endocannabinoid, 2-arachidonoyl-glycerol, and presynaptic cannabinoid CB1 receptor

Progress in brain cannabinoid CB 2 receptor research: From genes to behavior

Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina

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