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Palmitoylation-dependent activation of MC1R prevents melanomagenesis

Nature (London), 2017-09, Vol.549 (7672), p.399-403

2017

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Development of potent selective competitive-antagonists of the melanocortin type 2 receptor

Molecular and cellular endocrinology, 2014-08, Vol.394 (1-2), p.99-104

2014

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Biphasic Effect of Melanocortin Agonists on Metabolic Rate and Body Temperature

Cell metabolism, 2014-08, Vol.20 (2), p.333-345

2014

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Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects

The Journal of immunology (1950), 2015-04, Vol.194 (7), p.3381-3388

2015

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MC1R Functions, Expression, and Implications for Targeted Therapy

Journal of investigative dermatology, 2022-02, Vol.142 (2), p.293-302.e1

2022

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Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity

Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (1)

2021

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Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads

Nature communications, 2019-02, Vol.10 (1), p.877-10, Article 877

2019

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MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation

Pigment cell and melanoma research, 2014-09, Vol.27 (5), p.699-720

2014

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Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis

Nature communications, 2020-02, Vol.11 (1), p.745-745, Article 745

2020

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Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling

Nature medicine, 2013-07, Vol.19 (7), p.924-929

2013

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Single Amino Acid Mutation Contributes to Adaptive Beach Mouse Color Pattern

Science (American Association for the Advancement of Science), 2006-07, Vol.313 (5783), p.101-104

2006

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Both MC1 and MC3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion-Induced Neutrophil Recruitment

Arteriosclerosis, thrombosis, and vascular biology, 2015-09, Vol.35 (9), p.1936

2015

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Single-cell profiling of MC1R-inhibited melanocytes

Pigment cell and melanoma research, 2024-03, Vol.37 (2), p.291-308

2024

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Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5

PloS one, 2015-04, Vol.10 (4), p.e0123232-e0123232

2015

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An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

Nature (London), 2012-11, Vol.491 (7424), p.449-453

2012

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Distinct cAMP Signaling Microdomains Differentially Regulate Melanosomal pH and Pigmentation

Journal of investigative dermatology, 2023-10, Vol.143 (10), p.2019-2029.e3

2023

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Convergent changes in melanocortin receptor 1 gene are associated with black-headed coat color in sheep

Journal of animal science, 2023-01, Vol.101

2023

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Adaptation from standing genetic variation

Trends in ecology & evolution (Amsterdam), 2008, Vol.23 (1), p.38-44

2008

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Loss‐of‐function mutations in melanocortin-1 receptor modulate immune response in teleost fishes

Fish & shellfish immunology, 2022-12, Vol.131, p.838-846

2022

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The α‐melanocyte‐stimulating hormone/melanocortin‐1 receptor interaction: A driver of pleiotropic effects beyond pigmentation

Pigment cell and melanoma research, 2021-07, Vol.34 (4), p.748-761

2021

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UV Signaling Pathways within the Skin

Journal of investigative dermatology, 2014-08, Vol.134 (8), p.2080-2085

2014

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Germline MC1R status influences somatic mutation burden in melanoma

Nature communications, 2016-07, Vol.7 (1), p.12064-7, Article 12064

2016

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Selection on the Major Color Gene Melanocortin-1-Receptor Shaped the Evolution of the Melanocortin System Genes

International journal of molecular sciences, 2017-12, Vol.18 (12), p.2618

2017

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Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation

Pigment cell and melanoma research, 2014-07, Vol.27 (4), p.601-610

2014

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Palmitoylation-dependent activation of MC1R prevents melanomagenesis

Development of potent selective competitive-antagonists of the melanocortin type 2 receptor

Biphasic Effect of Melanocortin Agonists on Metabolic Rate and Body Temperature

Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects

MC1R Functions, Expression, and Implications for Targeted Therapy

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity

Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation

Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis

Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling

Single Amino Acid Mutation Contributes to Adaptive Beach Mouse Color Pattern

Both MC1 and MC3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion-Induced Neutrophil Recruitment

Single-cell profiling of MC1R-inhibited melanocytes

Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

Distinct cAMP Signaling Microdomains Differentially Regulate Melanosomal pH and Pigmentation

MC1R variants increased the risk of sporadic cutaneous melanoma in darker‐pigmented Caucasians: A pooled‐analysis from the M‐SKIP project

Convergent changes in melanocortin receptor 1 gene are associated with black-headed coat color in sheep

Adaptation from standing genetic variation

Loss‐of‐function mutations in melanocortin-1 receptor modulate immune response in teleost fishes

The α‐melanocyte‐stimulating hormone/melanocortin‐1 receptor interaction: A driver of pleiotropic effects beyond pigmentation

UV Signaling Pathways within the Skin

Germline MC1R status influences somatic mutation burden in melanoma

Selection on the Major Color Gene Melanocortin-1-Receptor Shaped the Evolution of the Melanocortin System Genes

Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation

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