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Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

Nature (London), 2012-05, Vol.485 (7399), p.465-470

2012

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Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes

Nature communications, 2021-03, Vol.12 (1), p.1564-1564, Article 1564

2021

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A non-linear system patterns Rab5 GTPase on the membrane

eLife, 2020-06, Vol.9

2020

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A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination

The Journal of cell biology, 2014-07, Vol.206 (2), p.307-328

2014

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Newcastle Disease Virus Entry into Chicken Macrophages via a pH-Dependent, Dynamin and Caveola-Mediated Endocytic Pathway That Requires Rab5

Journal of virology, 2021-06, Vol.95 (13), p.e0228820-e0228820

2021

Volltextzugriff (PDF)

HuR–miRNA complex activates RAS GTPase RalA to facilitate endosome targeting and extracellular export of miRNAs

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.105750-105750, Article 105750

2024

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HPIP and RUFY3 are noncanonical guanine nucleotide exchange factors of Rab5 to regulate endocytosis-coupled focal adhesion turnover

The Journal of biological chemistry, 2023-11, Vol.299 (11), p.105311-105311, Article 105311

2023

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The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

Cell, 2018-11, Vol.175 (4), p.1059-1073.e21

2018

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Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium

Cellular and molecular life sciences : CMLS, 2015-12, Vol.72 (24), p.4849-4866

2015

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Correlative single‐molecule localization microscopy and electron tomography reveals endosome nanoscale domains

Traffic (Copenhagen, Denmark), 2019-08, Vol.20 (8), p.601-617

2019

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Rab5 and Class III Phosphoinositide 3-Kinase Vps34 Are Involved in Hepatitis C Virus NS4B-Induced Autophagy

Journal of Virology, 2011-10, Vol.85 (20), p.10561-10571

2011

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CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

Journal of cell science, 2013-03, Vol.126 (Pt 6), p.1307-1316

2013

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lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma

Molecular therapy, 2022-03, Vol.30 (3), p.1071-1088

2022

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A genetic system to study Plasmodium falciparum protein function

Nature methods, 2017-04, Vol.14 (4), p.450

2017

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Preprint Highlight: The novel Rab5 effector FERRY links early endosomes with the translation machinery

Molecular biology of the cell, 2022-07, Vol.33 (8), p.mbcP22041001

Mantegazza, Adriana

2022

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A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ

Neuron (Cambridge, Mass.), 2019-10, Vol.104 (2), p.256-270.e5

2019

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Rab5-dependent autophagosome closure by ESCRT

The Journal of cell biology, 2019-06, Vol.218 (6), p.1908-1927

2019

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ATP9A deficiency causes ADHD and aberrant endosomal recycling via modulating RAB5 and RAB11 activity

Molecular psychiatry, 2023-03, Vol.28 (3), p.1219-1231

2023

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Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells

Journal of cell science, 2013-09, Vol.126 (Pt 17), p.3835-3847

2013

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The endocytic pathway taken by cationic substances requires Rab14 but not Rab5 and Rab7

Cell reports (Cambridge), 2021-11, Vol.37 (5), p.109945-109945, Article 109945

2021

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ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis

Autophagy, 2019-01, Vol.15 (1), p.34-57

2019

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A conserved and regulated mechanism drives endosomal Rab transition

eLife, 2020-05, Vol.9

2020

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Ehrlichia type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation

Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (38), p.E8977-E8986

2018

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Assessing Rab5 Activation in Health and Disease

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2293, p.273

2021

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Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and guanine nucleotide conversion

eLife, 2017-10, Vol.6

2017

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Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes

A non-linear system patterns Rab5 GTPase on the membrane

A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination

Newcastle Disease Virus Entry into Chicken Macrophages via a pH-Dependent, Dynamin and Caveola-Mediated Endocytic Pathway That Requires Rab5

HuR–miRNA complex activates RAS GTPase RalA to facilitate endosome targeting and extracellular export of miRNAs

HPIP and RUFY3 are noncanonical guanine nucleotide exchange factors of Rab5 to regulate endocytosis-coupled focal adhesion turnover

The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium

Correlative single‐molecule localization microscopy and electron tomography reveals endosome nanoscale domains

Rab5 and Class III Phosphoinositide 3-Kinase Vps34 Are Involved in Hepatitis C Virus NS4B-Induced Autophagy

CORVET and HOPS tethering complexes - coordinators of endosome and lysosome fusion

lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma

A genetic system to study Plasmodium falciparum protein function

Preprint Highlight: The novel Rab5 effector FERRY links early endosomes with the translation machinery

A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ

Rab5-dependent autophagosome closure by ESCRT

ATP9A deficiency causes ADHD and aberrant endosomal recycling via modulating RAB5 and RAB11 activity

Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells

The endocytic pathway taken by cationic substances requires Rab14 but not Rab5 and Rab7

ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis

A conserved and regulated mechanism drives endosomal Rab transition

Ehrlichia type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation

Assessing Rab5 Activation in Health and Disease

Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and guanine nucleotide conversion

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