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The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly

Molecular cell, 2014-09, Vol.55 (5), p.771-781

2014

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OsSUV3 dual helicase functions in salinity stress tolerance by maintaining photosynthesis and antioxidant machinery in rice (Oryza sativa L. cv. IR64)

The Plant journal : for cell and molecular biology, 2013-10, Vol.76 (1), p.115-127

2013

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Mitochondrial double-stranded RNA triggers antiviral signalling in humans

Nature (London), 2018-08, Vol.560 (7717), p.238-242

2018

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The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I

Molecular cell, 2008-02, Vol.29 (2), p.169-179

2008

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Innate immunity to virus infection

Immunological reviews, 2009-01, Vol.227 (1), p.75-86

2009

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RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes

Gut, 2022-05, Vol.71 (5), p.991-1005

2022

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Structure, function and regulation of spliceosomal RNA helicases

Current opinion in cell biology, 2012-06, Vol.24 (3), p.431-438

2012

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Acetylation of intrinsically disordered regions regulates phase separation

Nature chemical biology, 2019-01, Vol.15 (1), p.51-61

2019

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LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (4), p.1512-1517

2010

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RNA recognition and signal transduction by RIG-I-like receptors

Immunological reviews, 2009-01, Vol.227 (1), p.54-65

2009

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Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects

Cell host & microbe, 2018-03, Vol.23 (3), p.353-365.e8

2018

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Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation

Molecular cell, 2022-07, Vol.82 (14), p.2588-2603.e9

2022

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Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders

Nature (London), 2018-02, Vol.554 (7690), p.112-117

2018

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A loss‐of‐function homozygous mutation in DDX59 implicates a conserved DEAD‐box RNA helicase in nervous system development and function

Human mutation, 2018-02, Vol.39 (2), p.187-192

2018

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DEAD-box RNA Helicase DDX3: Functional Properties and Development of DDX3 Inhibitors as Antiviral and Anticancer Drugs

Molecules (Basel, Switzerland), 2020-02, Vol.25 (4), p.1015

2020

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Structure of a spliceosome remodelled for exon ligation

Nature (London), 2017-02, Vol.542 (7641), p.377-380

2017

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Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

Proceedings of the National Academy of Sciences - PNAS, 2007-01, Vol.104 (2), p.582-587

2007

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Superfamily 2 helicases

Frontiers in bioscience, 2012-06, Vol.17 (6), p.2070-2088

2012

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conformational plasticity of eukaryotic RNA‐dependent ATPases

The FEBS journal, 2015-03, Vol.282 (5), p.850-863

2015

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RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt-β-Catenin Signaling

Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6126), p.1436-1441

2013

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Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner

Science (American Association for the Advancement of Science), 2021-06, Vol.372 (6549), p.eabf6548-eabf6548

2021

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Structure of the human DICER–pre-miRNA complex in a dicing state

Nature (London), 2023-03, Vol.615 (7951), p.331-338

2023

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The RIG‐I‐like receptor LGP2 inhibits Dicer‐dependent processing of long double‐stranded RNA and blocks RNA interference in mammalian cells

The EMBO journal, 2018-02, Vol.37 (4), p.n/a

2018

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Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (30), p.1-12

2021

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The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly

OsSUV3 dual helicase functions in salinity stress tolerance by maintaining photosynthesis and antioxidant machinery in rice (Oryza sativa L. cv. IR64)

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I

Innate immunity to virus infection

RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes

Structure, function and regulation of spliceosomal RNA helicases

Acetylation of intrinsically disordered regions regulates phase separation

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

RNA recognition and signal transduction by RIG-I-like receptors

Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects

Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation

Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders

The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand RNA viruses

A loss‐of‐function homozygous mutation in DDX59 implicates a conserved DEAD‐box RNA helicase in nervous system development and function

DEAD-box RNA Helicase DDX3: Functional Properties and Development of DDX3 Inhibitors as Antiviral and Anticancer Drugs

Structure of a spliceosome remodelled for exon ligation

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

Superfamily 2 helicases

conformational plasticity of eukaryotic RNA‐dependent ATPases

RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt-β-Catenin Signaling

Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner

Structure of the human DICER–pre-miRNA complex in a dicing state

The RIG‐I‐like receptor LGP2 inhibits Dicer‐dependent processing of long double‐stranded RNA and blocks RNA interference in mammalian cells

Large-scale ratcheting in a bacterial DEAH/RHA-type RNA helicase that modulates antibiotics susceptibility

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