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RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges

Pharmacological reviews, 2020-10, Vol.72 (4), p.862-898

2020

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A Self-Assembled Platform Based on Branched DNA for sgRNA/Cas9/Antisense Delivery

Journal of the American Chemical Society, 2019-12, Vol.141 (48), p.19032-19037

2019

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Resolution of coronavirus disease 2019 (COVID-19)

Expert review of anti-infective therapy, 2020-12, Vol.18 (12), p.1201-1211

2020

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RNA-based pharmacotherapy for tumors: From bench to clinic and back

Biomedicine & pharmacotherapy, 2020-05, Vol.125, p.109997-109997, Article 109997

2020

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Natural antisense transcripts

Human molecular genetics, 2014-09, Vol.23 (R1), p.R54-R63

2014

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Emerging Gene and Small Molecule Therapies for the Neurodevelopmental Disorder Angelman Syndrome

Neurotherapeutics, 2021-07, Vol.18 (3), p.1535-1547

2021

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Myotonic dystrophy: approach to therapy

Current opinion in genetics & development, 2017-06, Vol.44, p.135-140

2017

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The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155―Dependent Pathway During Atherosclerosis

Circulation (New York, N.Y.), 2013-04, Vol.127 (15), p.1609-1619

2013

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Efficient Delivery of Therapeutic miRNA Nanocapsules for Tumor Suppression

Advanced materials (Weinheim), 2015-01, Vol.27 (2), p.292-297

2015

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Extracellular Vesicles Loaded with Long Antisense RNAs Repress Severe Acute Respiratory Syndrome Coronavirus 2 Infection

Nucleic acid therapeutics, 2024-06, Vol.34 (3), p.101-108

2024

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The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches--toward anti-sense therapy against TREDs

Nucleic acids research, 2016-02, Vol.44 (4), p.1937-1943

2016

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Long Non-Coding RNAs as Strategic Molecules to Augment the Radiation Therapy in Esophageal Squamous Cell Carcinoma

International journal of molecular sciences, 2020-09, Vol.21 (18), p.6787

2020

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The notorious R.N.A. in the spotlight - drug or target for the treatment of disease

RNA biology, 2017-05, Vol.14 (5), p.651-668

2017

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Tetrahedral Framework Nucleic Acid Delivered RNA Therapeutics Significantly Attenuate Pancreatic Cancer Progression via Inhibition of CTR1-Dependent Copper Absorption

ACS applied materials & interfaces, 2021-10, Vol.13 (39), p.46334-46342

2021

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Rationally designing antisense therapy to keep up with evolving bacterial resistance

PloS one, 2019-01, Vol.14 (1), p.e0209894-e0209894

2019

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STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers

International journal of oncology, 2012-10, Vol.41 (4), p.1181-1191

2012

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Stacking up CRISPR against RNAi for therapeutic gene inhibition

The FEBS journal, 2016-09, Vol.283 (17), p.3249-3260

Haussecker, Dirk

2016

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Non-coding RNAs as theranostics in human cancers

Journal of cellular biochemistry, 2012-05, Vol.113 (5), p.1451-1459

2012

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New therapeutic agents for acromegaly

Nature reviews. Endocrinology, 2016-02, Vol.12 (2), p.90-98

Melmed, Shlomo

2016

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Delivery of bifunctional RNAs that target an intronic repressor and increase SMN levels in an animal model of spinal muscular atrophy

Human molecular genetics, 2009-05, Vol.18 (9), p.1600-1611

2009

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New drugs for the treatment of Mycobacterium tuberculosis infection

Biomedicine & pharmacotherapy, 2017-07, Vol.91, p.546-558

2017

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Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Blood, 2013-11, Vol.122 (23), p.3825-3831

2013

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Telomerase inhibition in cancer therapeutics: molecular-based approaches

Current medicinal chemistry, 2006-10, Vol.13 (24), p.2875-2888

2006

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Genetics: The hexanucleotide hex

Nature (London), 2017-10, Vol.550 (7676), p.S106-S108

Dolgin, Elie

2017

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Antisense rescues babies from killer disease

Science (American Association for the Advancement of Science), 2016-12, Vol.354 (6318), p.1359-1360

Wadman, Meredith

2016

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RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges

A Self-Assembled Platform Based on Branched DNA for sgRNA/Cas9/Antisense Delivery

Resolution of coronavirus disease 2019 (COVID-19)

RNA-based pharmacotherapy for tumors: From bench to clinic and back

Natural antisense transcripts

Emerging Gene and Small Molecule Therapies for the Neurodevelopmental Disorder Angelman Syndrome

Myotonic dystrophy: approach to therapy

The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155―Dependent Pathway During Atherosclerosis

Efficient Delivery of Therapeutic miRNA Nanocapsules for Tumor Suppression

Extracellular Vesicles Loaded with Long Antisense RNAs Repress Severe Acute Respiratory Syndrome Coronavirus 2 Infection

The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches--toward anti-sense therapy against TREDs

Long Non-Coding RNAs as Strategic Molecules to Augment the Radiation Therapy in Esophageal Squamous Cell Carcinoma

The notorious R.N.A. in the spotlight - drug or target for the treatment of disease

Tetrahedral Framework Nucleic Acid Delivered RNA Therapeutics Significantly Attenuate Pancreatic Cancer Progression via Inhibition of CTR1-Dependent Copper Absorption

Rationally designing antisense therapy to keep up with evolving bacterial resistance

STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers

Stacking up CRISPR against RNAi for therapeutic gene inhibition

Non-coding RNAs as theranostics in human cancers

New therapeutic agents for acromegaly

Delivery of bifunctional RNAs that target an intronic repressor and increase SMN levels in an animal model of spinal muscular atrophy

New drugs for the treatment of Mycobacterium tuberculosis infection

Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Telomerase inhibition in cancer therapeutics: molecular-based approaches

Genetics: The hexanucleotide hex

Antisense rescues babies from killer disease

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