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Necroptosis in development and diseases

Genes & development, 2018-03, Vol.32 (5-6), p.327-340

2018

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Study on the mechanism of scutellarin's protective effect against ZEA-induced mouse ovarian granulosa cells injury

Food and chemical toxicology, 2022-12, Vol.170, p.113481, Article 113481

2022

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The Balance of TNF Mediated Pathways Regulates Inflammatory Cell Death Signaling in Healthy and Diseased Tissues

Frontiers in cell and developmental biology, 2020-05, Vol.8, p.365-365

2020

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New insights into the regulation of apoptosis, necroptosis, and pyroptosis by receptor interacting protein kinase 1 and caspase-8

Current opinion in cell biology, 2020-04, Vol.63, p.186-193

2020

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The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation

Immunity (Cambridge, Mass.), 2024-07, Vol.57 (7), p.1497-1513.e6

2024

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The protective role of Cordyceps cicadae and its active ingredient myriocin against sodium iodate-induced age-related macular degeneration via an anti-necroptotic TNF-RIPK1/3 pathway

Journal of ethnopharmacology, 2024-11, Vol.334, p.118565, Article 118565

2024

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Inhibitors Targeting RIPK1/RIPK3: Old and New Drugs

Trends in pharmacological sciences (Regular ed.), 2020-03, Vol.41 (3), p.209-224

2020

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Bifunctional halloysite nanotube-based Ripk1 siRNA delivery system rescues cognitive impairment by targeting amyloid β plaques for clearance and reducing necrotic neurons in Alzheimer’s disease mice

Chemical engineering journal (Lausanne, Switzerland : 1996), 2024-09, Vol.495, p.153460, Article 153460

2024

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Mitophagy-regulated Necroptosis plays a vital role in the nephrotoxicity of Fumonisin B1 in vivo and in vitro

Food and chemical toxicology, 2024-07, Vol.189, p.114714-114714, Article 114714

2024

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Novel insights into RIPK1 as a promising target for future Alzheimer’s disease treatment

Pharmacology & therapeutics (Oxford), 2022-03, Vol.231, p.107979-107979, Article 107979

2022

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Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group

Bioorganic & medicinal chemistry letters, 2019-06, Vol.29 (12), p.1497-1501

2019

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Corrigendum: RIPK1 in the inflammatory response and sepsis: recent advances, drug discovery and beyond

Frontiers in immunology, 2023, Vol.14, p.1332633-1332633

2023

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Programming inflammatory cell death for therapy

Pharmacology & therapeutics (Oxford), 2022-04, Vol.232, p.108010-108010, Article 108010

2022

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High glucose-induced apoptosis and necroptosis in podocytes is regulated by UCHL1 via RIPK1/RIPK3 pathway

Experimental cell research, 2019-09, Vol.382 (2), p.111463-111463, Article 111463

2019

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Necroptosis: A Novel Pathway in Neuroinflammation

Frontiers in pharmacology, 2021-07, Vol.12, p.701564-701564

2021

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Cell death checkpoints in the TNF pathway

Trends in immunology, 2023-08, Vol.44 (8), p.628-643

2023

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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

Immunity (Cambridge, Mass.), 2024-07, Vol.57 (7), p.1514-1532.e15

2024

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PM2.5 induces male reproductive toxicity via mitochondrial dysfunction, DNA damage and RIPK1 mediated apoptotic signaling pathway

The Science of the total environment, 2018-09, Vol.634, p.1435-1444

2018

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RIPK1 inhibitors: A key to unlocking the potential of necroptosis in drug development

European journal of medicinal chemistry, 2024-02, Vol.265, p.116123-116123, Article 116123

2024

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Cell death pathways: intricate connections and disease implications

The EMBO journal, 2021-03, Vol.40 (5), p.e106700-n/a

2021

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TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages

Frontiers in cell and developmental biology, 2019-05, Vol.7, p.91-91

2019

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The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

Frontiers in cellular and infection microbiology, 2020-06, Vol.10, p.238-238

2020

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Necrostatin-1 Prevents Necroptosis in Brains after Ischemic Stroke via Inhibition of RIPK1-Mediated RIPK3/MLKL Signaling

Aging and disease, 2019-08, Vol.10 (4), p.807-817

2019

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hsa‐miR‐500a‐3P alleviates kidney injury by targeting MLKL‐mediated necroptosis in renal epithelial cells

The FASEB journal, 2019-03, Vol.33 (3), p.3523-3535

2019

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Necroptosis in development and diseases

Study on the mechanism of scutellarin's protective effect against ZEA-induced mouse ovarian granulosa cells injury

The Balance of TNF Mediated Pathways Regulates Inflammatory Cell Death Signaling in Healthy and Diseased Tissues

New insights into the regulation of apoptosis, necroptosis, and pyroptosis by receptor interacting protein kinase 1 and caspase-8

The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation

The protective role of Cordyceps cicadae and its active ingredient myriocin against sodium iodate-induced age-related macular degeneration via an anti-necroptotic TNF-RIPK1/3 pathway

Inhibitors Targeting RIPK1/RIPK3: Old and New Drugs

Bifunctional halloysite nanotube-based Ripk1 siRNA delivery system rescues cognitive impairment by targeting amyloid β plaques for clearance and reducing necrotic neurons in Alzheimer’s disease mice

Mitophagy-regulated Necroptosis plays a vital role in the nephrotoxicity of Fumonisin B1 in vivo and in vitro

Novel insights into RIPK1 as a promising target for future Alzheimer’s disease treatment

Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group

Corrigendum: RIPK1 in the inflammatory response and sepsis: recent advances, drug discovery and beyond

Programming inflammatory cell death for therapy

High glucose-induced apoptosis and necroptosis in podocytes is regulated by UCHL1 via RIPK1/RIPK3 pathway

RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and Atherogenesis in Mice

Necroptosis: A Novel Pathway in Neuroinflammation

Cell death checkpoints in the TNF pathway

A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

PM2.5 induces male reproductive toxicity via mitochondrial dysfunction, DNA damage and RIPK1 mediated apoptotic signaling pathway

RIPK1 inhibitors: A key to unlocking the potential of necroptosis in drug development

Cell death pathways: intricate connections and disease implications

TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages

The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

Necrostatin-1 Prevents Necroptosis in Brains after Ischemic Stroke via Inhibition of RIPK1-Mediated RIPK3/MLKL Signaling

hsa‐miR‐500a‐3P alleviates kidney injury by targeting MLKL‐mediated necroptosis in renal epithelial cells

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