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Apixaban: A Clinical Pharmacokinetic and Pharmacodynamic Review

Clinical pharmacokinetics, 2019-10, Vol.58 (10), p.1265-1279

2019

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Electronic and Steric Tuning of a Prototypical Piano Stool Complex: Rh(III) Catalysis for C–H Functionalization

Accounts of chemical research, 2018-01, Vol.51 (1), p.170-180

2018

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Ligand-Enabled γ‑C(sp3)–H Activation of Ketones

Journal of the American Chemical Society, 2018-03, Vol.140 (10), p.3564-3568

2018

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Implications of Protein Interaction in the Speciation of Potential V IV O-Pyridinone Drugs

Inorganic chemistry, 2023-05, Vol.62 (21), p.8407-8417

2023

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Carbamoyl Pyridone HIV‑1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Journal of medicinal chemistry, 2013-07, Vol.56 (14), p.5901-5916

2013

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Novel hydroxypyridinone derivatives containing an oxime ether moiety: Synthesis, inhibition on mushroom tyrosinase and application in anti-browning of fresh-cut apples

Food chemistry, 2018-03, Vol.242, p.174-181

2018

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Structure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM

Nature (London), 2015-04, Vol.520 (7548), p.567-570

2015

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Ligand‐Promoted meta‐C−H Functionalization of Benzylamines

Angewandte Chemie (International ed.), 2017-04, Vol.56 (18), p.5125-5129

International ed. in English, 2017

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Tazemetostat: First Approval

Drugs (New York, N.Y.), 2020-04, Vol.80 (5), p.513-521

Hoy, Sheridan M.

2020

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Rhodium(III)-Catalyzed C–H Activation/Annulation with Vinyl Esters as an Acetylene Equivalent

Organic letters, 2014-09, Vol.16 (18), p.4718-4721

2014

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Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents

European journal of medicinal chemistry, 2018-02, Vol.145, p.35-40

2018

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4462-4475

2016

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Unexpected Cascade Sequence Forming the C(sp3)–N/C(sp2)–C(sp2) Bond: Direct Access to γ‑Lactam-Fused Pyridones with Anticancer Activity

Journal of organic chemistry, 2023-07, Vol.88 (13), p.7998-8009

2023

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Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

Science (American Association for the Advancement of Science), 2020-04, Vol.368 (6489), p.409-412

2020

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A 3,2-Hydroxypyridinone-based Decorporation Agent that Removes Uranium from Bones In Vivo

Nature communications, 2019-06, Vol.10 (1), p.2570-13, Article 2570

2019

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7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir

Angewandte Chemie (International ed.), 2018-06, Vol.57 (24), p.7181-7185

International ed. in English, 2018

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Structural basis for the action of the drug trametinib at KSR-bound MEK

Nature (London), 2020-12, Vol.588 (7838), p.509-514

2020

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Advances in Nickel-Catalyzed Cycloaddition Reactions To Construct Carbocycles and Heterocycles

Accounts of chemical research, 2015-08, Vol.48 (8), p.2354-2365

2015

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A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

Nature chemical biology, 2012-11, Vol.8 (11), p.890

2012

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Structure of human semicarbazide-sensitive amine oxidase/vascular adhesion protein-1

Acta crystallographica. Section D, Biological crystallography., 2005-11, Vol.61 (11), p.1550-1562

2005

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Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

Nature chemical biology, 2016-10, Vol.12 (10), p.779

2016

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Cobalt-catalyzed 2-(1-methylhydrazinyl)pyridine-assisted cyclization of thiophene-2-carbohydrazides with maleimides: efficient synthesis of thiophene-fused pyridones

Chemical communications (Cambridge, England), 2020-05, Vol.56 (41), p.5524-5527

2020

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Iterative Catalysis in the Biosynthesis of Mitochondrial Complex II Inhibitors Harzianopyridone and Atpenin B

Journal of the American Chemical Society, 2020-05, Vol.142 (19), p.8550-8554

2020

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Azaphilones as Activation‐Free Primary‐Amine‐Specific Bioconjugation Reagents for Peptides, Proteins and Lipids

Angewandte Chemie International Edition, 2022-02, Vol.61 (6), p.e202111783-n/a

International ed. in English, 2022

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Apixaban: A Clinical Pharmacokinetic and Pharmacodynamic Review

Electronic and Steric Tuning of a Prototypical Piano Stool Complex: Rh(III) Catalysis for C–H Functionalization

Ligand-Enabled γ‑C(sp3)–H Activation of Ketones

Implications of Protein Interaction in the Speciation of Potential V IV O-Pyridinone Drugs

Discovery of N‑(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro‑1H‑pyrrolo[2,3‑c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor

Carbamoyl Pyridone HIV‑1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Novel hydroxypyridinone derivatives containing an oxime ether moiety: Synthesis, inhibition on mushroom tyrosinase and application in anti-browning of fresh-cut apples

Structure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM

Ligand‐Promoted meta‐C−H Functionalization of Benzylamines

Tazemetostat: First Approval

Rhodium(III)-Catalyzed C–H Activation/Annulation with Vinyl Esters as an Acetylene Equivalent

Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents

Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

Unexpected Cascade Sequence Forming the C(sp3)–N/C(sp2)–C(sp2) Bond: Direct Access to γ‑Lactam-Fused Pyridones with Anticancer Activity

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

A 3,2-Hydroxypyridinone-based Decorporation Agent that Removes Uranium from Bones In Vivo

7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir

Structural basis for the action of the drug trametinib at KSR-bound MEK

Advances in Nickel-Catalyzed Cycloaddition Reactions To Construct Carbocycles and Heterocycles

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

Structure of human semicarbazide-sensitive amine oxidase/vascular adhesion protein-1

Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

Cobalt-catalyzed 2-(1-methylhydrazinyl)pyridine-assisted cyclization of thiophene-2-carbohydrazides with maleimides: efficient synthesis of thiophene-fused pyridones

Iterative Catalysis in the Biosynthesis of Mitochondrial Complex II Inhibitors Harzianopyridone and Atpenin B

Azaphilones as Activation‐Free Primary‐Amine‐Specific Bioconjugation Reagents for Peptides, Proteins and Lipids

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