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Structure and function of an RNase H domain at the heart of the spliceosome

The EMBO journal, 2008-11, Vol.27 (21), p.2929-2940

2008

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Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions

Genes & development, 2000-05, Vol.14 (9), p.1098-1108

2000

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The question remains: Is the spliceosome a ribozyme?

Nature structural & molecular biology, 2000-10, Vol.7 (10), p.850-854

2000

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Minimization of a eukaryotic mini-intein

Biochemical and biophysical research communications, 2008-02, Vol.366 (1), p.239-243

2008

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Functional Contacts With a Range of Splicing Proteins Suggest a Central Role for Brr2p in the Dynamic Control of the Order of Events in Spliceosomes of Saccharomyces cerevisiae

Genetics (Austin), 2001-04, Vol.157 (4), p.1451-1467

2001

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Trans-splicing of an artificially split fungal mini-intein

Biochemical and biophysical research communications, 2007-04, Vol.355 (3), p.830-834

2007

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Suppressors of a Cold-Sensitive Mutation in Yeast U4 RNA Define Five Domains in the Splicing Factor Prp8 That Influence Spliceosome Activation

Genetics (Austin), 2000-08, Vol.155 (4), p.1667-1682

2000

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Prp8 intein in fungal pathogens: target for potential antifungal drugs

FEBS letters, 2004-08, Vol.572 (1-3), p.46-50

2004

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Characterization of U6 snRNA–protein interactions

RNA (Cambridge), 1999-11, Vol.5 (11), p.1470-1481, Article S1355838299991355

1999

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The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p

RNA (Cambridge), 2001-11, Vol.7 (11), p.1554-1565

2001

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Inteins and introns within the prp8 -gene of four Eupenicillium species

Journal of basic microbiology, 2009-02, Vol.49 (1), p.52-57

2009

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New Roles for the Snp1 and Exo84 Proteins in Yeast Pre-mRNA Splicing

The Journal of biological chemistry, 2001-08, Vol.276 (33), p.31004-31015

2001

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Evidence for a role of Sky1p-mediated phosphorylation in 3′ splice site recognition involving both Prp8 and Prp17/Slu4

RNA (Cambridge), 2001-09, Vol.7 (9), p.1284-1297, Article S1355838201016077

2001

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Small-molecule inhibitors for the Prp8 intein as antifungal agents

Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (2)

2021

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F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening

Structure (London), 2020-06, Vol.28 (6), p.694-706.e5

2020

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Prp8 impacts cryptic but not alternative splicing frequency

Proceedings of the National Academy of Sciences - PNAS, 2019-02, Vol.116 (6), p.2193-2199

2019

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Prp8 positioning of U5 snRNA is linked to 5' splice site recognition

RNA (Cambridge), 2018-06, Vol.24 (6), p.769-777

2018

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Prp8 regulates oncogene-induced hyperplastic growth in Drosophila

Development (Cambridge), 2018-11, Vol.145 (22)

2018

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PRP4 Kinase Domain Loss Nullifies Drug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells

Molecules and Cells, 2020, 43(7), , pp.662-670

2020

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Nineteen complex-related factor Prp45 is required for the early stages of cotranscriptional spliceosome assembly

RNA (Cambridge), 2017-10, Vol.23 (10), p.1512-1524

2017

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A close-up look at the spliceosome, at last

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (17), p.4288-4293

Abelson, John

2017

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PRP8 Intein in Onygenales: Distribution and Phylogenetic Aspects

Mycopathologia (1975), 2020-02, Vol.185 (1), p.37-49

2020

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Transcriptomic comparison of Drosophila snRNP biogenesis mutants reveals mutant-specific changes in pre-mRNA processing: implications for spinal muscular atrophy

RNA (Cambridge), 2016-08, Vol.22 (8), p.1215-1227

2016

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Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase

RNA (Cambridge), 2011-05, Vol.17 (5), p.799-808

2011

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Cisplatin protects mice from challenge of Cryptococcus neoformans by targeting the Prp8 intein

Emerging microbes & infections, 2019-01, Vol.8 (1), p.895-908

2019

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Structure and function of an RNase H domain at the heart of the spliceosome

Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions

The question remains: Is the spliceosome a ribozyme?

Minimization of a eukaryotic mini-intein

Functional Contacts With a Range of Splicing Proteins Suggest a Central Role for Brr2p in the Dynamic Control of the Order of Events in Spliceosomes of Saccharomyces cerevisiae

Trans-splicing of an artificially split fungal mini-intein

Suppressors of a Cold-Sensitive Mutation in Yeast U4 RNA Define Five Domains in the Splicing Factor Prp8 That Influence Spliceosome Activation

Prp8 intein in fungal pathogens: target for potential antifungal drugs

Characterization of U6 snRNA–protein interactions

The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p

Inteins and introns within the prp8 -gene of four Eupenicillium species

New Roles for the Snp1 and Exo84 Proteins in Yeast Pre-mRNA Splicing

Evidence for a role of Sky1p-mediated phosphorylation in 3′ splice site recognition involving both Prp8 and Prp17/Slu4

Small-molecule inhibitors for the Prp8 intein as antifungal agents

F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening

Prp8 impacts cryptic but not alternative splicing frequency

Prp8 positioning of U5 snRNA is linked to 5' splice site recognition

Prp8 regulates oncogene-induced hyperplastic growth in Drosophila

PRP4 Kinase Domain Loss Nullifies Drug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells

Nineteen complex-related factor Prp45 is required for the early stages of cotranscriptional spliceosome assembly

A close-up look at the spliceosome, at last

PRP8 Intein in Onygenales: Distribution and Phylogenetic Aspects

Transcriptomic comparison of Drosophila snRNP biogenesis mutants reveals mutant-specific changes in pre-mRNA processing: implications for spinal muscular atrophy

Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase

Cisplatin protects mice from challenge of Cryptococcus neoformans by targeting the Prp8 intein

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