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Low-Density Lipoprotein Cholesterol Lowering for the Primary Prevention of Cardiovascular Disease Among Men With Primary Elevations of Low-Density Lipoprotein Cholesterol Levels of 190 mg/dL or Above: Analyses From the WOSCOPS (West of Scotland Coronary Prevention Study) 5-Year Randomized Trial and 20-Year Observational Follow-Up

Circulation (New York, N.Y.), 2017-11, Vol.136 (20), p.1878-1891

2017

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Impact of Farnesylation Inhibitors on Survival in Hutchinson-Gilford Progeria Syndrome

Circulation (New York, N.Y.), 2014-07, Vol.130 (1), p.27-34

2014

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atg7-Based Autophagy Activation Reverses Doxorubicin-Induced Cardiotoxicity

Circulation research, 2021-10, Vol.129 (8), p.e166-e182

2021

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Effects of Pravastatin on Human Placenta, Endothelium, and Women With Severe Preeclampsia

Hypertension (Dallas, Tex. 1979), 2015-09, Vol.66 (3), p.687-697

2015

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Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

Pharmaceutical research, 2012-10, Vol.29 (10), p.2860-2873

2012

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Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway

International immunopharmacology, 2021-11, Vol.100, p.108077-108077, Article 108077

2021

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C-Reactive Protein Levels and Outcomes after Statin Therapy

The New England journal of medicine, 2005-01, Vol.352 (1), p.20-28

2005

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Use of mechanistic modeling to assess interindividual variability and interspecies differences in active uptake in human and rat hepatocytes

Drug metabolism and disposition, 2012-09, Vol.40 (9), p.1744-1756

2012

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Role of Complement Component C1q in the Onset of Preeclampsia in Mice

Hypertension (Dallas, Tex. 1979), 2011-10, Vol.58 (4), p.716-724

2011

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Effect of pravastatin on total kidney volume, left ventricular mass index, and microalbuminuria in pediatric autosomal dominant polycystic kidney disease

Clinical journal of the American Society of Nephrology, 2014-05, Vol.9 (5), p.889-896

2014

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Statins and Antimicrobial Effects: Simvastatin as a Potential Drug against Staphylococcus aureus Biofilm

PloS one, 2015-05, Vol.10 (5), p.e0128098-e0128098

2015

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Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

Nature Medicine, 2008-07, Vol.14 (7), p.767-772

2008

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Statin Effects on Vascular Calcification: Microarchitectural Changes in Aortic Calcium Deposits in Aged Hyperlipidemic Mice

Arteriosclerosis, thrombosis, and vascular biology, 2021-04, Vol.41 (4), p.e185

2021

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Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (4), p.1451-1455

2011

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Statins Stimulate New Myocyte Formation After Myocardial Infarction by Activating Growth and Differentiation of the Endogenous Cardiac Stem Cells

International journal of molecular sciences, 2020-10, Vol.21 (21), p.7927

2020

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Pravastatin for Preventing and Treating Preeclampsia: A Systematic Review

Obstetrical & gynecological survey, 2018-01, Vol.73 (1), p.40-55

2018

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Selective Growth Suppressive Effect of Pravastatin on Senescent Human Lung Fibroblasts

Pharmazie, 2022-05, Vol.77 (5), p.132-136

2022

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Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

Pharmacogenetics and genomics, 2007-08, Vol.17 (8), p.647-656

2007

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Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor- β Signaling in Human Endothelial Cells

The Journal of pharmacology and experimental therapeutics, 2021-02, Vol.376 (2), p.148-160

2021

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Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1

Clinical pharmacology and therapeutics, 2016-11, Vol.100 (5), p.524-536

2016

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Pancreatic islet blood flow is selectively enhanced by captopril, irbesartan and pravastatin, and suppressed by palmitate

Biochemical and biophysical research communications, 2006-07, Vol.346 (1), p.26-32

2006

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Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress

Scientific reports, 2017-09, Vol.7 (1), p.11863-17, Article 11863

2017

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Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3

Drug metabolism and disposition, 2007-08, Vol.35 (8), p.1308-1314

2007

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Pravastatin Attenuates Hypertension, Oxidative Stress, and Angiogenic Imbalance in Rat Model of Placental Ischemia-Induced Hypertension

Hypertension (Dallas, Tex. 1979), 2013-05, Vol.61 (5), p.1103-1110

2013

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Biphasic influence of pravastatin on human cardiac microvascular endothelial cell functions under pathological and physiological conditions

Biochemical and biophysical research communications, 2019-04, Vol.511 (2), p.476-481

2019

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Impact of Farnesylation Inhibitors on Survival in Hutchinson-Gilford Progeria Syndrome

atg7-Based Autophagy Activation Reverses Doxorubicin-Induced Cardiotoxicity

Effects of Pravastatin on Human Placenta, Endothelium, and Women With Severe Preeclampsia

Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway

C-Reactive Protein Levels and Outcomes after Statin Therapy

Use of mechanistic modeling to assess interindividual variability and interspecies differences in active uptake in human and rat hepatocytes

Role of Complement Component C1q in the Onset of Preeclampsia in Mice

Effect of pravastatin on total kidney volume, left ventricular mass index, and microalbuminuria in pediatric autosomal dominant polycystic kidney disease

Statins and Antimicrobial Effects: Simvastatin as a Potential Drug against Staphylococcus aureus Biofilm

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

Statin Effects on Vascular Calcification: Microarchitectural Changes in Aortic Calcium Deposits in Aged Hyperlipidemic Mice

Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model

Statins Stimulate New Myocyte Formation After Myocardial Infarction by Activating Growth and Differentiation of the Endogenous Cardiac Stem Cells

Pravastatin for Preventing and Treating Preeclampsia: A Systematic Review

Selective Growth Suppressive Effect of Pravastatin on Senescent Human Lung Fibroblasts

Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor- β Signaling in Human Endothelial Cells

Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1

Pancreatic islet blood flow is selectively enhanced by captopril, irbesartan and pravastatin, and suppressed by palmitate

Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress

Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3

Pravastatin Attenuates Hypertension, Oxidative Stress, and Angiogenic Imbalance in Rat Model of Placental Ischemia-Induced Hypertension

Biphasic influence of pravastatin on human cardiac microvascular endothelial cell functions under pathological and physiological conditions

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