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Anti-prion activity of an RNA aptamer and its structural basis

Nucleic acids research, 2013-01, Vol.41 (2), p.1355

2013

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Cryo-EM structure of an amyloid fibril formed by full-length human prion protein

Nature structural & molecular biology, 2020-06, Vol.27 (6), p.598

2020

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Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked

Nature communications, 2014-07, Vol.5 (1), p.4347, Article 4347

2014

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An optimized Western blot assay provides a comprehensive assessment of the physiological endoproteolytic processing of the prion protein

The Journal of biological chemistry, 2023-02, Vol.299 (2), p.102823-102823, Article 102823

2023

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General Model of Prion Strains and Their Pathogenicity

Science (American Association for the Advancement of Science), 2007-11, Vol.318 (5852), p.930-936

2007

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The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

The EMBO journal, 2011-05, Vol.30 (10), p.2057-2070

2011

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Generating a Prion with Bacterially Expressed Recombinant Prion Protein

Science (American Association for the Advancement of Science), 2010-02, Vol.327 (5969), p.1132-1135

2010

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Interaction between Human Prion Protein and Amyloid-β (Aβ) Oligomers: ROLE OF N-TERMINAL RESIDUES

The Journal of biological chemistry, 2010-08, Vol.285 (34), p.26377-26383

2010

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Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models

The Journal of biological chemistry, 2015-07, Vol.290 (28), p.17415-17438

2015

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Prions

Cold Spring Harbor perspectives in biology, 2011-01, Vol.3 (1), p.a006833-a006833

2011

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A New Paradigm for Enzymatic Control of α-Cleavage and β-Cleavage of the Prion Protein

The Journal of biological chemistry, 2014-01, Vol.289 (2), p.803-813

2014

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The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein

Nature (London), 2013-09, Vol.501 (7465), p.102-106

2013

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RT-QuIC Assays for Prion Disease Detection and Diagnostics

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1658, p.185

2017

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α2,3 linkage of sialic acid to a GPI anchor and an unpredicted GPI attachment site in human prion protein

The Journal of biological chemistry, 2020-05, Vol.295 (22), p.7789-7798

2020

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Therapeutic Molecules and Endogenous Ligands Regulate the Interaction between Brain Cellular Prion Protein (PrPC) and Metabotropic Glutamate Receptor 5 (mGluR5)

The Journal of biological chemistry, 2014-10, Vol.289 (41), p.28460-28477

2014

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In Vitro Generation of Infectious Scrapie Prions

Cell, 2005-04, Vol.121 (2), p.195-206

2005

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From Kuru to Alzheimer: A personal outlook

Protein science, 2021-09, Vol.30 (9), p.1776-1792

Brunori, Maurizio

2021

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High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease

Brain (London, England : 1878), 2014-03, Vol.137 (Pt 3), p.873-886

2014

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The N-terminus of the prion protein is a toxic effector regulated by the C-terminus

eLife, 2017-05, Vol.6

2017

Volltextzugriff (PDF)

Antibody binding increases the flexibility of the prion protein

Biochimica et biophysica acta. Proteins and proteomics, 2022-11, Vol.1870 (11-12), p.140827, Article 140827

2022

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Role of prion protein glycosylation in replication of human prions by protein misfolding cyclic amplification

Laboratory investigation, 2019-11, Vol.99 (11), p.1741-1748

2019

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Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models

European journal of medicinal chemistry, 2023-01, Vol.245 (Pt 1), p.114923, Article 114923

2023

Volltextzugriff (PDF)

Prion Strain Mutation Determined by Prion Protein Conformational Compatibility and Primary Structure

Science (American Association for the Advancement of Science), 2010-05, Vol.328 (5982), p.1154-1158

2010

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Sialylation of prion protein controls the rate of prion amplification, the cross-species barrier, the ratio of PrPSc glycoform and prion infectivity

PLoS pathogens, 2014-09, Vol.10 (9), p.e1004366-e1004366

2014

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Ellagic acid and pentagalloylglucose are potential inhibitors of prion protein fibrillization

International journal of biological macromolecules, 2021-03, Vol.172, p.371-380

2021

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Anti-prion activity of an RNA aptamer and its structural basis

Cryo-EM structure of an amyloid fibril formed by full-length human prion protein

Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked

An optimized Western blot assay provides a comprehensive assessment of the physiological endoproteolytic processing of the prion protein

General Model of Prion Strains and Their Pathogenicity

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

Generating a Prion with Bacterially Expressed Recombinant Prion Protein

Interaction between Human Prion Protein and Amyloid-β (Aβ) Oligomers: ROLE OF N-TERMINAL RESIDUES

Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models

Prions

A New Paradigm for Enzymatic Control of α-Cleavage and β-Cleavage of the Prion Protein

The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein

RT-QuIC Assays for Prion Disease Detection and Diagnostics

α2,3 linkage of sialic acid to a GPI anchor and an unpredicted GPI attachment site in human prion protein

Therapeutic Molecules and Endogenous Ligands Regulate the Interaction between Brain Cellular Prion Protein (PrPC) and Metabotropic Glutamate Receptor 5 (mGluR5)

In Vitro Generation of Infectious Scrapie Prions

From Kuru to Alzheimer: A personal outlook

High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease

The N-terminus of the prion protein is a toxic effector regulated by the C-terminus

Antibody binding increases the flexibility of the prion protein

Role of prion protein glycosylation in replication of human prions by protein misfolding cyclic amplification

Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models

Prion Strain Mutation Determined by Prion Protein Conformational Compatibility and Primary Structure

Sialylation of prion protein controls the rate of prion amplification, the cross-species barrier, the ratio of PrPSc glycoform and prion infectivity

Ellagic acid and pentagalloylglucose are potential inhibitors of prion protein fibrillization

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