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Piperine: A review of its biological effects

Phytotherapy research, 2021-02, Vol.35 (2), p.680-700

2021

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Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity

Journal of pharmaceutical sciences, 2015-10, Vol.104 (10), p.3544-3556

2015

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Formulation and evaluation of dissolving microneedle for transdermal delivery of piperine: the effect of polymers concentration

Journal of biomaterials science. Polymer ed., 2024-06, Vol.35 (8), p.1177-1196

2024

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Piperine as a Potential Anti-cancer Agent: A Review on Preclinical Studies

Current medicinal chemistry, 2018-01, Vol.25 (37), p.4918-4928

2018

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Piperine-loaded nanoparticles with enhanced dissolution and oral bioavailability for epilepsy control

European journal of pharmaceutical sciences, 2019-09, Vol.137, p.104988, Article 104988

2019

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Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in human subjects: a randomised, double-blind, placebo-controlled, cross-over investigation

British journal of nutrition, 2014-07, Vol.112 (2), p.203-213

2014

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Triple Strategies to Improve Oral Bioavailability by Fabricating Coamorphous Forms of Ursolic Acid with Piperine: Enhancing Water-Solubility, Permeability, and Inhibiting Cytochrome P450 Isozymes

Molecular pharmaceutics, 2020-12, Vol.17 (12), p.4443-4462

2020

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Manumycin polyketides act as molecular glues between UBR7 and P53

Nature chemical biology, 2020-11, Vol.16 (11), p.1189-1198

2020

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Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis

Clinical nutrition (Edinburgh, Scotland), 2015-12, Vol.34 (6), p.1101-1108

2015

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Simultaneous UPLC–MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: Minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012-02, Vol.883-884 (3), p.161-171

2012

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The effect of Pro NanoLipospheres (PNL) formulation containing natural absorption enhancers on the oral bioavailability of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in a rat model

European journal of pharmaceutical sciences, 2017-11, Vol.109, p.21-30

2017

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Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (Bioperine ® ) and Potential Applications

Nutrients, 2020-06, Vol.12 (6), p.1886

2020

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Identification and optimization of piperine analogues as neuroprotective agents for the treatment of Parkinson’s disease via the activation of Nrf2/keap1 pathway

European journal of medicinal chemistry, 2020-08, Vol.199, p.112385, Article 112385

2020

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Piper nigrum and Piperine: An Update

Phytotherapy research, 2013-08, Vol.27 (8), p.1121-1130

2013

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Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences

Scientific reports, 2016-12, Vol.6 (1), p.39239, Article 39239

2016

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In-tube solid-phase microextraction directly coupled to tandem mass spectrometry for anandamide and 2-arachidonoylglycerol determination in rat brain samples from an animal model of Parkinson's disease

Journal of Chromatography A, 2021-01, Vol.1636, p.461766, Article 461766

2021

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Piperine: Old Spice and New Nutraceutical?

Current pharmaceutical design, 2019-01, Vol.25 (15), p.1729-1739

2019

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Effect of piperine on inhibition of FFA induced TLR4 mediated inflammation and amelioration of acetic acid induced ulcerative colitis in mice

Journal of ethnopharmacology, 2015-04, Vol.164, p.239-246

2015

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Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies

European journal of medicinal chemistry, 2020-01, Vol.185, p.111770, Article 111770

2020

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A Delightful Trip Along the Pathway of Cannabinoid and Endocannabinoid Chemistry and Pharmacology

Annual review of pharmacology and toxicology, 2023-01, Vol.63 (1), p.1-13

Mechoulam, Raphael

2023

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Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling

Journal of natural products (Washington, D.C.), 2020-10, Vol.83 (10), p.3041-3049

2020

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Co-delivery of rapamycin- and piperine-loaded polymeric nanoparticles for breast cancer treatment

Drug delivery, 2016-09, Vol.23 (7), p.2608-2616

2016

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Increased Oral Bioavailability of Piperine from an Optimized Piper nigrum Nanosuspension

Planta medica, 2019-02, Vol.85 (3), p.249-257

2019

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Formulation of piperine solid lipid nanoparticles (SLN) for treatment of rheumatoid arthritis

Drug development and industrial pharmacy, 2017-06, Vol.43 (6), p.1003-1010

2017

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GPR55 inhibits the pro-adipogenic activity of anandamide in human adipose stromal cells

Experimental cell research, 2024-02, Vol.435 (1), p.113908, Article 113908

2024

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Piperine: A review of its biological effects

Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity

Formulation and evaluation of dissolving microneedle for transdermal delivery of piperine: the effect of polymers concentration

Piperine as a Potential Anti-cancer Agent: A Review on Preclinical Studies

Piperine-loaded nanoparticles with enhanced dissolution and oral bioavailability for epilepsy control

Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in human subjects: a randomised, double-blind, placebo-controlled, cross-over investigation

Triple Strategies to Improve Oral Bioavailability by Fabricating Coamorphous Forms of Ursolic Acid with Piperine: Enhancing Water-Solubility, Permeability, and Inhibiting Cytochrome P450 Isozymes

Manumycin polyketides act as molecular glues between UBR7 and P53

Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis

Simultaneous UPLC–MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: Minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction

The effect of Pro NanoLipospheres (PNL) formulation containing natural absorption enhancers on the oral bioavailability of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in a rat model

Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (Bioperine ® ) and Potential Applications

Identification and optimization of piperine analogues as neuroprotective agents for the treatment of Parkinson’s disease via the activation of Nrf2/keap1 pathway

Piper nigrum and Piperine: An Update

Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences

In-tube solid-phase microextraction directly coupled to tandem mass spectrometry for anandamide and 2-arachidonoylglycerol determination in rat brain samples from an animal model of Parkinson's disease

Piperine: Old Spice and New Nutraceutical?

Effect of piperine on inhibition of FFA induced TLR4 mediated inflammation and amelioration of acetic acid induced ulcerative colitis in mice

Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies

A Delightful Trip Along the Pathway of Cannabinoid and Endocannabinoid Chemistry and Pharmacology

Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling

Co-delivery of rapamycin- and piperine-loaded polymeric nanoparticles for breast cancer treatment

Increased Oral Bioavailability of Piperine from an Optimized Piper nigrum Nanosuspension

Formulation of piperine solid lipid nanoparticles (SLN) for treatment of rheumatoid arthritis

GPR55 inhibits the pro-adipogenic activity of anandamide in human adipose stromal cells

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