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Turning liabilities into opportunities: Off-target based drug repurposing in cancer

Seminars in cancer biology, 2021-01, Vol.68, p.209-229

2021

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Dual or multi-targeting inhibitors: The next generation anticancer agents

European journal of medicinal chemistry, 2018-01, Vol.143, p.1277-1300

2018

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A Perspective on Multi-target Drugs for Alzheimer’s Disease

Trends in pharmacological sciences (Regular ed.), 2020-07, Vol.41 (7), p.434-445

2020

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Sulfonamide derivatives as multi-target agents for complex diseases

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2042-2050

2019

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5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology

Cell, 2018-02, Vol.172 (4), p.719-730.e14

2018

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From combinations to multitarget‐directed ligands: A continuum in Alzheimer's disease polypharmacology

Medicinal research reviews, 2021-09, Vol.41 (5), p.2606-2633

2021

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Drug combination therapy increases successful drug repositioning

Drug discovery today, 2016-07, Vol.21 (7), p.1189-1195

2016

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Polypharmacology: challenges and opportunities in drug discovery

Journal of medicinal chemistry, 2014-10, Vol.57 (19), p.7874-7887

2014

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Polypharmacology – Foe or Friend?

Journal of medicinal chemistry, 2013-11, Vol.56 (22), p.8955-8971

Peters, Jens-Uwe

2013

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The therapeutic potential of second and third generation CB1R antagonists

Pharmacology & therapeutics (Oxford), 2020-04, Vol.208, p.107477-107477, Article 107477

2020

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Hybrid molecules: The privileged scaffolds for various pharmaceuticals

European journal of medicinal chemistry, 2016-11, Vol.124, p.500-536

2016

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Polypharmacological drug actions of recently FDA approved antibiotics

European journal of medicinal chemistry, 2021-01, Vol.209, p.112931-112931, Article 112931

2021

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Molecular Docking: Shifting Paradigms in Drug Discovery

International journal of molecular sciences, 2019-09, Vol.20 (18), p.4331

2019

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Piecing together aminergic polypharmacology

Cell research, 2024-09, Vol.34 (9), p.599-600

2024

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In silico methods to address polypharmacology: current status, applications and future perspectives

Drug discovery today, 2016-02, Vol.21 (2), p.288-298

2016

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Polypharmacology: The science of multi-targeting molecules

Pharmacological research, 2022-02, Vol.176, p.106055-106055, Article 106055

2022

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An up-to-date overview of computational polypharmacology in modern drug discovery

Expert opinion on drug discovery, 2020-09, Vol.15 (9), p.1025-1044

2020

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Front Cover: Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation (ChemMedChem 11/2020)

ChemMedChem, 2020-06, Vol.15 (11), p.906-906

2020

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Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation

Journal of medicinal chemistry, 2020-08, Vol.63 (16), p.8723-8737

2020

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Recent Updates on Obesity Treatments: Available Drugs and Future Directions

Neuroscience, 2020-06, Vol.437, p.215-239

2020

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100 Years of Suramin

Antimicrobial agents and chemotherapy, 2020-02, Vol.64 (3)

2020

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Computational polypharmacology: a new paradigm for drug discovery

Expert opinion on drug discovery, 2017-03, Vol.12 (3), p.279-291

2017

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Uncovering the Oxidative Stress Mechanisms and Targets in Alzheimer's Disease by Integrating Phenotypic Screening Data and Polypharmacology Networks

Journal of Alzheimer's disease, 2024-01, Vol.99 (s1), p.S139-S156

2024

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Inside Back Cover: Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology (Angew. Chem. Int. Ed. 30/2015)

Angewandte Chemie (International ed.), 2015-07, Vol.54 (30), p.8847-8847

International ed. in English, 2015

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Epigenetic polypharmacology: A new frontier for epi‐drug discovery

Medicinal research reviews, 2020-01, Vol.40 (1), p.190-244

2020

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Turning liabilities into opportunities: Off-target based drug repurposing in cancer

Dual or multi-targeting inhibitors: The next generation anticancer agents

A Perspective on Multi-target Drugs for Alzheimer’s Disease

Sulfonamide derivatives as multi-target agents for complex diseases

5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology

From combinations to multitarget‐directed ligands: A continuum in Alzheimer's disease polypharmacology

Drug combination therapy increases successful drug repositioning

Polypharmacology: challenges and opportunities in drug discovery

Polypharmacology – Foe or Friend?

The therapeutic potential of second and third generation CB1R antagonists

Hybrid molecules: The privileged scaffolds for various pharmaceuticals

Polypharmacological drug actions of recently FDA approved antibiotics

Molecular Docking: Shifting Paradigms in Drug Discovery

Piecing together aminergic polypharmacology

In silico methods to address polypharmacology: current status, applications and future perspectives

Polypharmacology: The science of multi-targeting molecules

An up-to-date overview of computational polypharmacology in modern drug discovery

Front Cover: Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation (ChemMedChem 11/2020)

Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation

Recent Updates on Obesity Treatments: Available Drugs and Future Directions

100 Years of Suramin

Computational polypharmacology: a new paradigm for drug discovery

Uncovering the Oxidative Stress Mechanisms and Targets in Alzheimer's Disease by Integrating Phenotypic Screening Data and Polypharmacology Networks

Inside Back Cover: Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology (Angew. Chem. Int. Ed. 30/2015)

Epigenetic polypharmacology: A new frontier for epi‐drug discovery

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