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Exploiting poly(I:C) to induce cancer cell apoptosis

Cancer biology & therapy, 2017-10, Vol.18 (10), p.747-756

2017

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Poly(I:C) as cancer vaccine adjuvant: knocking on the door of medical breakthroughs

Pharmacology & therapeutics (Oxford), 2015-02, Vol.146, p.120-131

2015

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Vaccine adjuvant uses of poly-IC and derivatives

Expert review of vaccines, 2015-03, Vol.14 (3), p.447-459

2015

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Immune responses and outcome after vaccination with glioma-associated antigen peptides and poly-ICLC in a pilot study for pediatric recurrent low-grade gliomas

Neuro-oncology (Charlottesville, Va.), 2016-08, Vol.18 (8), p.1157-1168

2016

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Development of PLGA nanoparticle loaded dissolving microneedles and comparison with hollow microneedles in intradermal vaccine delivery

European journal of pharmaceutics and biopharmaceutics, 2018-08, Vol.129, p.111-121

2018

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Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

The Journal of experimental medicine, 2011-11, Vol.208 (12), p.2357-2366

2011

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Influence of poly(I:C) variability on thermoregulation, immune responses and pregnancy outcomes in mouse models of maternal immune activation

Brain, behavior, and immunity, 2019-08, Vol.80, p.406-418

2019

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A double-blind, placebo-controlled, randomized, clinical trial of the TLR-3 agonist rintatolimod in severe cases of chronic fatigue syndrome

PloS one, 2012-03, Vol.7 (3), p.e31334

2012

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Polymeric nanoparticles for co-delivery of synthetic long peptide antigen and poly IC as therapeutic cancer vaccine formulation

Journal of controlled release, 2015-04, Vol.203, p.16-22

2015

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Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes

Nature communications, 2021-06, Vol.12 (1), p.3958-20, Article 3958

2021

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In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (38), p.15745-15750

2011

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Stress in Puberty Unmasks Latent Neuropathological Consequences of Prenatal Immune Activation in Mice

Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6123), p.1095-1099

2013

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Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant

Advanced drug delivery reviews, 2013-10, Vol.65 (10), p.1386-1399

2013

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Synergistic effects of stellated fibrous mesoporous silica and synthetic dsRNA analogues for cancer immunotherapy

Chemical communications (Cambridge, England), 2018, Vol.54 (9), p.1057-1060

2018

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Phosphorothioate modification of the TLR9 ligand CpG ODN inhibits poly(I:C)-induced apoptosis of hepatocellular carcinoma by entry blockade

Cancer letters, 2014-12, Vol.355 (1), p.76-84

2014

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Therapeutic Immune Modulation against Solid Cancers with Intratumoral Poly-ICLC: A Pilot Trial

Clinical cancer research, 2018-10, Vol.24 (20), p.4937-4948

2018

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A novel RNA‐based adjuvant combines strong immunostimulatory capacities with a favorable safety profile

International journal of cancer, 2015-07, Vol.137 (2), p.372-384

2015

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Effect of toll-like receptor 3 agonist poly I:C on intestinal mucosa and epithelial barrier function in mouse models of acute colitis

World journal of gastroenterology : WJG, 2017-02, Vol.23 (6), p.999-1009

2017

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Encapsulation of two different TLR ligands into liposomes confer protective immunity and prevent tumor development

Journal of controlled release, 2017-02, Vol.247, p.134-144

2017

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Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor‐conditioned macrophages

European journal of immunology, 2019-05, Vol.49 (5), p.801-811

2019

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Toll-like receptor 3 promotes cross-priming to virus-infected cells

Nature, 2005-02, Vol.433 (7028), p.887-892

2005

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Polyinosinic: polycytidylic acid induced inflammation enhances while lipopolysaccharide diminishes alloimmunity to platelet transfusion in mice

Frontiers in immunology, 2023-12, Vol.14, p.1281130-1281130

2023

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Ampligen: A potential toll-like 3 receptor adjuvant for immunotherapy of cancer

Vaccine, 2009-05, Vol.27 (25), p.3401-3404

2009

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Efficacy of rintatolimod in the treatment of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)

Expert review of clinical pharmacology, 2016-06, Vol.9 (6), p.755-770

Mitchell, William M

2016

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To poly(I:C) or not to poly(I:C): Advancing preclinical schizophrenia research through the use of prenatal immune activation models

Neuropharmacology, 2012-03, Vol.62 (3), p.1308-1321

2012

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