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PITX2‐dependent gene regulation in atrial fibrillation and rhythm control

The Journal of physiology, 2017-06, Vol.595 (12), p.4019-4026

2017

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Pitx2 suppression at meiotic stages associates with seasonal inhibition of testis development in Rattus norvegicus caraco

Integrative zoology, 2023-05, Vol.18 (3), p.543-551

2023

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A missense mutation in Pitx2 leads to early-onset glaucoma via NRF2-YAP1 axis

Cell death & disease, 2021-10, Vol.12 (11), p.1017-1017, Article 1017

2021

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A PITX2 splice-site mutation in a family with Axenfeld-Rieger syndrome leads to decreased expression of nuclear PITX2 protein

International ophthalmology, 2021-04, Vol.41 (4), p.1503-1511

2021

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A novel frameshift mutation in the PITX2 gene in a family with Axenfeld-Rieger syndrome using targeted exome sequencing

BMC medical genetics, 2019-06, Vol.20 (1), p.105-105, Article 105

2019

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Dosage requirement of Pitx2 for development of multiple organs

Development (Cambridge), 1999-10, Vol.126 (20), p.4643-4651

1999

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Loss of abdominal muscle in Pitx2 mutants associated with altered axial specification of lateral plate mesoderm

PloS one, 2012-07, Vol.7 (7), p.e42228-e42228

2012

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The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

Developmental cell, 2013-01, Vol.24 (2), p.206-214

2013

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A cellular atlas of Pitx2- dependent cardiac development

Development (Cambridge), 2019-06, Vol.146 (12)

2019

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Long-range Pitx2c enhancer–promoter interactions prevent predisposition to atrial fibrillation

Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (45), p.22692-22698

2019

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Atrial fibrillation and left atrial size and function: a Mendelian randomization study

Scientific reports, 2021-04, Vol.11 (1), p.8431-8431, Article 8431

2021

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Corneal Plana-Like Phenotype With Peripheral Scleralization Associated With a Pathogenic Variant of PITX2 : A Case Report

Cornea, 2023-05, Vol.42 (5), p.639-640

2023

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HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis

The Journal of biological chemistry, 2022-09, Vol.298 (9), p.102295-102295, Article 102295

2022

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Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development

The Journal of biological chemistry, 2023-11, Vol.299 (11), p.105324-105324, Article 105324

2023

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LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells

Biomaterials, 2021-11, Vol.278, p.121133-121133, Article 121133

2021

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Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury

Nature (London), 2016-06, Vol.534 (7605), p.119-123

2016

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Pitx2-Sox2-Lef1 interactions specify progenitor oral/dental epithelial cell signaling centers

Development (Cambridge), 2020-06, Vol.147 (11)

2020

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N-Cadherin, a Cell Adhesion Molecule Involved in Establishment of Embryonic Left-Right Asymmetry

Science (American Association for the Advancement of Science), 2000-05, Vol.288 (5468), p.1047-1051

2000

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Pitx2 impairs calcium handling in a dose-dependent manner by modulating Wnt signalling

Cardiovascular research, 2016-01, Vol.109 (1), p.55-66

2016

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Genotype-phenotype association of PITX2 and FOXC1 in Axenfeld-Rieger syndrome

Experimental eye research, 2023-01, Vol.226, p.109307-109307, Article 109307

2023

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Integrating Genetic, Transcriptional, and Functional Analyses to Identify 5 Novel Genes for Atrial Fibrillation

Circulation (New York, N.Y.), 2014-10, Vol.130 (15), p.1225-1235

2014

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The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation

Development (Cambridge), 2013-08, Vol.140 (16), p.3348-3359

2013

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PITX2 functions as a transcription factor for GPX4 and protects pancreatic cancer cells from ferroptosis

Experimental cell research, 2024-06, Vol.439 (1), p.114074, Article 114074

2024

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Complex balanced intrachromosomal rearrangement involving PITX2 identified as a cause of Axenfeld‐Rieger Syndrome

American journal of medical genetics. Part A, 2024-05, Vol.194 (5), p.e63542-n/a

2024

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Wnt signaling regulates pancreatic β cell proliferation

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (15), p.6247-6252

2007

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PITX2‐dependent gene regulation in atrial fibrillation and rhythm control

Pitx2 suppression at meiotic stages associates with seasonal inhibition of testis development in Rattus norvegicus caraco

A missense mutation in Pitx2 leads to early-onset glaucoma via NRF2-YAP1 axis

A PITX2 splice-site mutation in a family with Axenfeld-Rieger syndrome leads to decreased expression of nuclear PITX2 protein

A novel frameshift mutation in the PITX2 gene in a family with Axenfeld-Rieger syndrome using targeted exome sequencing

Dosage requirement of Pitx2 for development of multiple organs

Loss of abdominal muscle in Pitx2 mutants associated with altered axial specification of lateral plate mesoderm

The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

A cellular atlas of Pitx2- dependent cardiac development

Long-range Pitx2c enhancer–promoter interactions prevent predisposition to atrial fibrillation

Atrial fibrillation and left atrial size and function: a Mendelian randomization study

Corneal Plana-Like Phenotype With Peripheral Scleralization Associated With a Pathogenic Variant of PITX2 : A Case Report

HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis

Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development

LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells

Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury

Pitx2-Sox2-Lef1 interactions specify progenitor oral/dental epithelial cell signaling centers

N-Cadherin, a Cell Adhesion Molecule Involved in Establishment of Embryonic Left-Right Asymmetry

Pitx2 impairs calcium handling in a dose-dependent manner by modulating Wnt signalling

Genotype-phenotype association of PITX2 and FOXC1 in Axenfeld-Rieger syndrome

Integrating Genetic, Transcriptional, and Functional Analyses to Identify 5 Novel Genes for Atrial Fibrillation

The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation

PITX2 functions as a transcription factor for GPX4 and protects pancreatic cancer cells from ferroptosis

Complex balanced intrachromosomal rearrangement involving PITX2 identified as a cause of Axenfeld‐Rieger Syndrome

Wnt signaling regulates pancreatic β cell proliferation

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