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Flavin Monooxygenase-Generated N-Hydroxypipecolic Acid Is a Critical Element of Plant Systemic Immunity

Cell, 2018-04, Vol.173 (2), p.456-469.e16

2018

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Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke)

Stroke (1970), 2017-06, Vol.48 (6), p.1608-1616

2017

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Antiapicoplast and Gametocytocidal Screening To Identify the Mechanisms of Action of Compounds within the Malaria Box

Antimicrobial Agents and Chemotherapy, 2014-02, Vol.58 (2), p.811-819

2014

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Monitoring Direct Thrombin Inhibitors With Calibrated Diluted Thrombin Time vs Activated Partial Thromboplastin Time in Pediatric Patients

American journal of clinical pathology, 2023-01, Vol.159 (1), p.60-68

2023

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N‐hydroxypipecolic acid induces systemic acquired resistance and transcriptional reprogramming via TGA transcription factors

Plant, cell and environment, 2023-06, Vol.46 (6), p.1900-1920

2023

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Pipecolic acid confers systemic immunity by regulating free radicals

Science advances, 2018-05, Vol.4 (5), p.eaar4509-eaar4509

2018

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Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19

Cardiovascular drugs and therapy, 2021-04, Vol.35 (2), p.195-203

2021

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How to dose and monitor argatroban for treatment of HIT

British journal of haematology, 2022-06, Vol.197 (6), p.653-655

Warkentin, Theodore E.

2022

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Head-to-head ex vivo comparison of clinically used direct anticoagulant drugs

Naunyn-Schmiedeberg's archives of pharmacology, 2024-06, Vol.397 (6), p.4461-4470

2024

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Argatroban pharmacokinetics and pharmacodynamics in critically ill cardiac surgical patients with suspected heparin-induced thrombocytopenia

Thrombosis and haemostasis, 2016-06, Vol.115 (6), p.1081

2016

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Pipecolic esters as minimized templates for proteasome inhibition

Organic & biomolecular chemistry, 2019-03, Vol.17 (10), p.2734-2746

2019

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Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2410-2422

2016

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G-Quadruplex Aptamers to Human Thrombin Versus Other Direct Thrombin Inhibitors: The Focus on Mechanism of Action and Drug Efficiency as Anticoagulants

Current medicinal chemistry, 2016-01, Vol.23 (21), p.2230

2016

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NbALD1 mediates resistance to turnip mosaic virus by regulating the accumulation of salicylic acid and the ethylene pathway in Nicotiana benthamiana

Molecular plant pathology, 2019-07, Vol.20 (7), p.990-1004

2019

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The first total synthesis of the cyclodepsipeptide pipecolidepsin A

Nature communications, 2013, Vol.4 (1), p.2352-2352, Article 2352

2013

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Total Syntheses of Tubulysins

Chemistry : a European journal, 2010-10, Vol.16 (38), p.11678-11688

2010

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Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52

Journal of medicinal chemistry, 2012-05, Vol.55 (9), p.4123-4131

2012

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The Effects of the Combined Argatroban/Nitric Oxide-Releasing Polymer on Platelet Microparticle-Induced Thrombogenicity in Coated Extracorporeal Circuits

ASAIO journal (1992), 2021-05, Vol.67 (5), p.573-582

2021

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Cyclic RGD peptidomimetics containing 4- and 5-amino-cyclopropane pipecolic acid (CPA) templates as dual αVβ3 and α5β1 integrin ligands

Bioorganic & medicinal chemistry, 2016-02, Vol.24 (4), p.703-711

2016

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First Total Synthesis of Tubulysin B

Organic letters, 2009-12, Vol.11 (24), p.5567-5569

2009

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Anticoagulation for Extracorporeal Life Support: Direct Thrombin Inhibitors and Heparin

ASAIO journal (1992), 2015-11, Vol.61 (6), p.652-655

2015

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Comparison of the aPTT with alternative tests for monitoring direct thrombin inhibitors in patient samples

American journal of clinical pathology, 2014-05, Vol.141 (5), p.665-674

2014

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Caution in Using the Activated Partial Thromboplastin Time to Monitor Argatroban in COVID-19 and Vaccine-Induced Immune Thrombocytopenia and Thrombosis (VITT)

Clinical and applied thrombosis/hemostasis, 2021-12, Vol.27, p.10760296211066945-10760296211066945

2021

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Thrombin inhibitor argatroban modulates bone marrow stromal cells behaviors and promotes osteogenesis through canonical Wnt signaling

Life sciences (1973), 2021-03, Vol.269, p.119073-119073, Article 119073

2021

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Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure–activity studies

Bioorganic & medicinal chemistry letters, 2015-04, Vol.25 (7), p.1515-1519

2015

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Flavin Monooxygenase-Generated N-Hydroxypipecolic Acid Is a Critical Element of Plant Systemic Immunity

Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke)

Antiapicoplast and Gametocytocidal Screening To Identify the Mechanisms of Action of Compounds within the Malaria Box

Monitoring Direct Thrombin Inhibitors With Calibrated Diluted Thrombin Time vs Activated Partial Thromboplastin Time in Pediatric Patients

N‐hydroxypipecolic acid induces systemic acquired resistance and transcriptional reprogramming via TGA transcription factors

Pipecolic acid confers systemic immunity by regulating free radicals

Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19

How to dose and monitor argatroban for treatment of HIT

Head-to-head ex vivo comparison of clinically used direct anticoagulant drugs

Argatroban pharmacokinetics and pharmacodynamics in critically ill cardiac surgical patients with suspected heparin-induced thrombocytopenia

Pipecolic esters as minimized templates for proteasome inhibition

Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51

G-Quadruplex Aptamers to Human Thrombin Versus Other Direct Thrombin Inhibitors: The Focus on Mechanism of Action and Drug Efficiency as Anticoagulants

NbALD1 mediates resistance to turnip mosaic virus by regulating the accumulation of salicylic acid and the ethylene pathway in Nicotiana benthamiana

The first total synthesis of the cyclodepsipeptide pipecolidepsin A

Total Syntheses of Tubulysins

Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52

The Effects of the Combined Argatroban/Nitric Oxide-Releasing Polymer on Platelet Microparticle-Induced Thrombogenicity in Coated Extracorporeal Circuits

Cyclic RGD peptidomimetics containing 4- and 5-amino-cyclopropane pipecolic acid (CPA) templates as dual αVβ3 and α5β1 integrin ligands

First Total Synthesis of Tubulysin B

Anticoagulation for Extracorporeal Life Support: Direct Thrombin Inhibitors and Heparin

Comparison of the aPTT with alternative tests for monitoring direct thrombin inhibitors in patient samples

Caution in Using the Activated Partial Thromboplastin Time to Monitor Argatroban in COVID-19 and Vaccine-Induced Immune Thrombocytopenia and Thrombosis (VITT)

Thrombin inhibitor argatroban modulates bone marrow stromal cells behaviors and promotes osteogenesis through canonical Wnt signaling

Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure–activity studies

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