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Phthalides and Phthalans: Synthetic Methodologies and Their Applications in the Total Synthesis

Chemical reviews, 2014-06, Vol.114 (12), p.6213-6284

2014

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Design and Synthesis of N -phenyl Phthalimides as Potent Protoporphyrinogen Oxidase Inhibitors

Molecules (Basel, Switzerland), 2019-11, Vol.24 (23), p.4363

2019

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Thiazole, Isatin and Phthalimide Derivatives Tested in vivo against Cancer Models: A Literature Review of the Last Six Years

Current medicinal chemistry, 2024-01, Vol.31 (20), p.2991-3032

2024

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Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13487-13509

2021

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Benzylic C–H heteroarylation of N -(benzyloxy)phthalimides with cyanopyridines enabled by photoredox 1,2-hydrogen atom transfer

Chemical communications (Cambridge, England), 2020-07, Vol.56 (61), p.8671-8674

2020

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Synthesis of 2-(2-(4-thioxo-3H-1,2-dithiole-5-yl) phenoxy)ethyl)isoindole-1,3-thione, a novel hydrogen sulfide-releasing phthalimide hybrid, and evaluation of its activity in models of inflammatory pain

European journal of pharmacology, 2023-01, Vol.938, p.175409, Article 175409

2023

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Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: Anti-inflammatory and analgesic activities

European journal of medicinal chemistry, 2015-03, Vol.92, p.115-123

2015

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Microwave-promoted facile access to 4-aminoquinoline-phthalimides: Synthesis and anti-plasmodial evaluation

European journal of medicinal chemistry, 2018-01, Vol.143, p.150-156

2018

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Light‐Harvesting Supramolecular Phosphors: Highly Efficient Room Temperature Phosphorescence in Solution and Hydrogels

Angewandte Chemie International Edition, 2021-09, Vol.60 (36), p.19720-19724

International ed. in English, 2021

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Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus

The New England journal of medicine, 2022-03, Vol.386 (11), p.1034-1045

2022

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Design, Synthesis, and Herbicidal Activity of Novel Diphenyl Ether Derivatives Containing Fast Degrading Tetrahydrophthalimide

Journal of agricultural and food chemistry, 2020-03, Vol.68 (12), p.3729-3741

2020

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Design, synthesis and biological evaluation of phthalimide-alkylamine derivatives as balanced multifunctional cholinesterase and monoamine oxidase-B inhibitors for the treatment of Alzheimer’s disease

Bioorganic & medicinal chemistry letters, 2017-11, Vol.27 (22), p.5053-5059

2017

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Accelerating reaction generality and mechanistic insight through additive mapping

Science (American Association for the Advancement of Science), 2022-04, Vol.376 (6592), p.532-539

2022

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Ruthenium(II)-Catalyzed CH Activation with Isocyanates: A Versatile Route to Phthalimides

Chemistry : a European journal, 2014-10, Vol.20 (43), p.13932-13936

2014

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C2-symmetric cyclic selenium-catalyzed enantioselective bromoaminocyclization

Journal of the American Chemical Society, 2013-01, Vol.135 (4), p.1232-1235

2013

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Synthesis and biological activity of new phthalimides as potential anti-inflammatory agents

Bioorganic & medicinal chemistry, 2017-07, Vol.25 (13), p.3396-3405

2017

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Constructing Quaternary Carbons from N‑(Acyloxy)phthalimide Precursors of Tertiary Radicals Using Visible-Light Photocatalysis

Journal of organic chemistry, 2015-06, Vol.80 (12), p.6025-6036

2015

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Photoredox Synthesis of Thio‐Functionalized Cyclic Ethers Using N‐Sulfenyl Phthalimides as a Thiyl‐Radical Precursor

Chinese journal of chemistry, 2023-08, Vol.41 (15), p.1823-1828

2023

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Cover Feature: N ‐(aminobenzyliden)phthalimides as a New Redox Mediator Family for the Selective Indirect Reduction of Benzyl or Allyl Halides (ChemCatChem 15/2023)

ChemCatChem, 2023-08, Vol.15 (15)

2023

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Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.1259-1270

2019

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Probing and evaluating transmembrane chloride ion transport in double walled trifluorophenyl/phthalimide extended calix[4]pyrrole-based supramolecular receptors

Journal of materials chemistry. B, Materials for biology and medicine, 2024-06, Vol.12 (24), p.595-5956

2024

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Photoredox Decarboxylative Alkylation/(2+2+1) Cycloaddition of 1,7‐Enynes: A Cascade Approach Towards Polycyclic Heterocycles Using N‐(Acyloxy)phthalimides as Radical Source

Advanced synthesis & catalysis, 2019-12, Vol.361 (24), p.5558-5564

2019

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Flumioxazin, a PPO inhibitor: A weight-of-evidence consideration of its mode of action as a developmental toxicant in the rat and its relevance to humans

Toxicology (Amsterdam), 2022-04, Vol.472, p.153160-153160, Article 153160

2022

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Sterically Controlled, Palladium-Catalyzed Intermolecular Amination of Arenes

Journal of the American Chemical Society, 2013-06, Vol.135 (23), p.8480-8483

2013

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Phenotypic screening reveals a highly selective phthalimide-based compound with antileishmanial activity

PLoS neglected tropical diseases, 2024-03, Vol.18 (3), p.e0012050-e0012050

2024

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Phthalides and Phthalans: Synthetic Methodologies and Their Applications in the Total Synthesis

Design and Synthesis of N -phenyl Phthalimides as Potent Protoporphyrinogen Oxidase Inhibitors

Thiazole, Isatin and Phthalimide Derivatives Tested in vivo against Cancer Models: A Literature Review of the Last Six Years

Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer

Benzylic C–H heteroarylation of N -(benzyloxy)phthalimides with cyanopyridines enabled by photoredox 1,2-hydrogen atom transfer

Synthesis of 2-(2-(4-thioxo-3H-1,2-dithiole-5-yl) phenoxy)ethyl)isoindole-1,3-thione, a novel hydrogen sulfide-releasing phthalimide hybrid, and evaluation of its activity in models of inflammatory pain

Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: Anti-inflammatory and analgesic activities

Microwave-promoted facile access to 4-aminoquinoline-phthalimides: Synthesis and anti-plasmodial evaluation

Light‐Harvesting Supramolecular Phosphors: Highly Efficient Room Temperature Phosphorescence in Solution and Hydrogels

Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus

Design, Synthesis, and Herbicidal Activity of Novel Diphenyl Ether Derivatives Containing Fast Degrading Tetrahydrophthalimide

Design, synthesis and biological evaluation of phthalimide-alkylamine derivatives as balanced multifunctional cholinesterase and monoamine oxidase-B inhibitors for the treatment of Alzheimer’s disease

Accelerating reaction generality and mechanistic insight through additive mapping

Ruthenium(II)-Catalyzed CH Activation with Isocyanates: A Versatile Route to Phthalimides

C2-symmetric cyclic selenium-catalyzed enantioselective bromoaminocyclization

Synthesis and biological activity of new phthalimides as potential anti-inflammatory agents

Constructing Quaternary Carbons from N‑(Acyloxy)phthalimide Precursors of Tertiary Radicals Using Visible-Light Photocatalysis

Photoredox Synthesis of Thio‐Functionalized Cyclic Ethers Using N‐Sulfenyl Phthalimides as a Thiyl‐Radical Precursor

Cover Feature: N ‐(aminobenzyliden)phthalimides as a New Redox Mediator Family for the Selective Indirect Reduction of Benzyl or Allyl Halides (ChemCatChem 15/2023)

Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies

Probing and evaluating transmembrane chloride ion transport in double walled trifluorophenyl/phthalimide extended calix[4]pyrrole-based supramolecular receptors

Photoredox Decarboxylative Alkylation/(2+2+1) Cycloaddition of 1,7‐Enynes: A Cascade Approach Towards Polycyclic Heterocycles Using N‐(Acyloxy)phthalimides as Radical Source

Flumioxazin, a PPO inhibitor: A weight-of-evidence consideration of its mode of action as a developmental toxicant in the rat and its relevance to humans

Sterically Controlled, Palladium-Catalyzed Intermolecular Amination of Arenes

Phenotypic screening reveals a highly selective phthalimide-based compound with antileishmanial activity

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