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Metabolic disposition and biological significance of simple phenols of dietary origin: hydroxytyrosol and tyrosol

Drug metabolism reviews, 2016-05, Vol.48 (2), p.218-236

2016

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Dose-dependent metabolic disposition of hydroxytyrosol and formation of mercapturates in rats

Pharmacological research, 2013-11, Vol.77, p.47-56

2013

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Gender differences in plasma and urine metabolites from Sprague–Dawley rats after oral administration of normal and high doses of hydroxytyrosol, hydroxytyrosol acetate, and DOPAC

European journal of nutrition, 2017-02, Vol.56 (1), p.215-224

2017

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The effect of polyphenols in olive oil on heart disease risk factors: a randomized trial

Annals of internal medicine, 2006-09, Vol.145 (5), p.333

2006

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Protection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humans

The American journal of clinical nutrition, 2012-05, Vol.95 (5), p.1238-1244

2012

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The metabolism of salidroside to its aglycone p-tyrosol in rats following the administration of salidroside

PloS one, 2014-08, Vol.9 (8), p.e103648

2014

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Generation of the Antioxidant Hydroxytyrosol from Tyrosol Present in Beer and Red Wine in a Randomized Clinical Trial

Nutrients, 2019-09, Vol.11 (9), p.2241

2019

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Moderate consumption of wine, through both its phenolic compounds and alcohol content, promotes hydroxytyrosol endogenous generation in humans. A randomized controlled trial

Molecular nutrition & food research, 2015-06, Vol.59 (6), p.1213-1216

2015

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Assessing Validity of Self-Reported Dietary Intake within a Mediterranean Diet Cluster Randomized Controlled Trial among US Firefighters

Nutrients, 2019-09, Vol.11 (9), p.2250

2019

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Application of dried spot cards as a rapid sample treatment method for determining hydroxytyrosol metabolites in human urine samples. Comparison with microelution solid-phase extraction

Analytical and bioanalytical chemistry, 2013-11, Vol.405 (28), p.9179-9192

2013

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Olive oil phenolics are dose-dependently absorbed in humans

FEBS letters, 2000-02, Vol.468 (2), p.159-160

2000

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Pharmacokinetics and metabolism of hydroxytyrosol, a natural antioxidant from olive oil

Drug metabolism and disposition, 2001-11, Vol.29 (11), p.1492

2001

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Ethanol induces hydroxytyrosol formation in humans

Pharmacological research, 2015-05, Vol.95-96, p.27-33

2015

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Anti-Inflammatory Effect of White Wine in CKD Patients and Healthy Volunteers

Blood purification, 2015-01, Vol.39 (1-3), p.218-223

2015

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Olive Oil Phenols Are Absorbed in Humans

The Journal of nutrition, 2002-03, Vol.132 (3), p.409-417

2002

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Tyrosol and hydroxytyrosol are absorbed from moderate and sustained doses of virgin olive oil in humans

European journal of clinical nutrition, 2003-01, Vol.57 (1), p.186-190

2003

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Hydroxytyrosol Excretion Differs between Rats and Humans and Depends on the Vehicle of Administration

The Journal of nutrition, 2003-08, Vol.133 (8), p.2612-2615

2003

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Hydroxytyrosol Administration Enhances Atherosclerotic Lesion Development in Apo E Deficient Mice

Journal of biochemistry (Tokyo), 2006-09, Vol.140 (3), p.383-391

2006

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Effects of differing phenolic content in dietary olive oils on lipids and LDL oxidation: A randomized controlled trial

European journal of nutrition, 2004-06, Vol.43 (3), p.140-147

2004

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The In Vivo Fate of Hydroxytyrosol and Tyrosol, Antioxidant Phenolic Constituents of Olive Oil, after Intravenous and Oral Dosing of Labeled Compounds to Rats

The Journal of nutrition, 2001-07, Vol.131 (7), p.1993-1996

2001

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Liquid chromatography–tandem mass spectrometry analysis of oleuropein and its metabolite hydroxytyrosol in rat plasma and urine after oral administration

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003-02, Vol.785 (1), p.47-56

2003

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Urinary excretion of olive oil phenols and their metabolites in humans

Metabolism, clinical and experimental, 2001-12, Vol.50 (12), p.1426-1428

2001

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The Pharmacokinetics of Phenylethyl Alcohol (PEA): Safety Evaluation Comparisons in Rats, Rabbits, and Humans

International journal of toxicology, 2013-01, Vol.32 (1), p.39-47

2013

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Strategies for ascertaining the interference of phase II metabolites co-eluting with parent compounds using LC-MS/MS

Journal of separation science, 2013-08, Vol.36 (16), p.2584-2592

2013

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Protective effect of homovanillyl alcohol on cardiovascular disease and total mortality: virgin olive oil, wine, and catechol-methylation

The American journal of clinical nutrition, 2017-06, Vol.105 (6), p.1297-1304

2017

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Metabolic disposition and biological significance of simple phenols of dietary origin: hydroxytyrosol and tyrosol

Dose-dependent metabolic disposition of hydroxytyrosol and formation of mercapturates in rats

Gender differences in plasma and urine metabolites from Sprague–Dawley rats after oral administration of normal and high doses of hydroxytyrosol, hydroxytyrosol acetate, and DOPAC

The effect of polyphenols in olive oil on heart disease risk factors: a randomized trial

Protection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humans

The metabolism of salidroside to its aglycone p-tyrosol in rats following the administration of salidroside

Generation of the Antioxidant Hydroxytyrosol from Tyrosol Present in Beer and Red Wine in a Randomized Clinical Trial

Moderate consumption of wine, through both its phenolic compounds and alcohol content, promotes hydroxytyrosol endogenous generation in humans. A randomized controlled trial

Assessing Validity of Self-Reported Dietary Intake within a Mediterranean Diet Cluster Randomized Controlled Trial among US Firefighters

Application of dried spot cards as a rapid sample treatment method for determining hydroxytyrosol metabolites in human urine samples. Comparison with microelution solid-phase extraction

Olive oil phenolics are dose-dependently absorbed in humans

Pharmacokinetics and metabolism of hydroxytyrosol, a natural antioxidant from olive oil

Ethanol induces hydroxytyrosol formation in humans

Anti-Inflammatory Effect of White Wine in CKD Patients and Healthy Volunteers

Olive Oil Phenols Are Absorbed in Humans

Tyrosol and hydroxytyrosol are absorbed from moderate and sustained doses of virgin olive oil in humans

Hydroxytyrosol Excretion Differs between Rats and Humans and Depends on the Vehicle of Administration

Hydroxytyrosol Administration Enhances Atherosclerotic Lesion Development in Apo E Deficient Mice

Effects of differing phenolic content in dietary olive oils on lipids and LDL oxidation: A randomized controlled trial

The In Vivo Fate of Hydroxytyrosol and Tyrosol, Antioxidant Phenolic Constituents of Olive Oil, after Intravenous and Oral Dosing of Labeled Compounds to Rats

Liquid chromatography–tandem mass spectrometry analysis of oleuropein and its metabolite hydroxytyrosol in rat plasma and urine after oral administration

Urinary excretion of olive oil phenols and their metabolites in humans

The Pharmacokinetics of Phenylethyl Alcohol (PEA): Safety Evaluation Comparisons in Rats, Rabbits, and Humans

Strategies for ascertaining the interference of phase II metabolites co-eluting with parent compounds using LC-MS/MS

Protective effect of homovanillyl alcohol on cardiovascular disease and total mortality: virgin olive oil, wine, and catechol-methylation

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