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Physiological and Pharmacological Roles of PTH and PTHrP in Bone Using Their Shared Receptor, PTH1R

Endocrine reviews, 2021-08, Vol.42 (4), p.383-406

2021

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Binding Selectivity of Abaloparatide for PTH-Type-1-Receptor Conformations and Effects on Downstream Signaling

Endocrinology (Philadelphia), 2016-01, Vol.157 (1), p.141-149

2016

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Abaloparatide, the second generation osteoanabolic drug: Molecular mechanisms underlying its advantages over the first-in-class teriparatide

Biochemical pharmacology, 2019-08, Vol.166, p.185-191

2019

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Abaloparatide: A review of preclinical and clinical studies

European journal of pharmacology, 2021-10, Vol.909, p.174409-174409, Article 174409

Brent, Mikkel Bo

2021

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PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer

Cell metabolism, 2016-02, Vol.23 (2), p.315-323

2016

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Effects of Abaloparatide, a Human Parathyroid Hormone-Related Peptide Analog, on Bone Mineral Density in Postmenopausal Women with Osteoporosis

The journal of clinical endocrinology and metabolism, 2015-02, Vol.100 (2), p.697-706

2015

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Acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals

Acta Physiologica, 2022-06, Vol.235 (2), p.e13815-n/a

2022

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Regulation of WNT5A and WNT11 during MSC in vitro chondrogenesis: WNT inhibition lowers BMP and hedgehog activity, and reduces hypertrophy

Cellular and molecular life sciences : CMLS, 2019-10, Vol.76 (19), p.3875-3889

2019

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Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1

Acta pharmacologica Sinica, 2023-06, Vol.44 (6), p.1227-1237

2023

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Precisely Controlled Delivery of Abaloparatide through Injectable Hydrogel to Promote Bone Regeneration

Macromolecular bioscience, 2019-06, Vol.19 (6), p.e1900020-n/a

2019

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Abaloparatide: First Global Approval

Drugs (New York, N.Y.), 2017-08, Vol.77 (12), p.1363-1368

Shirley, Matt

2017

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Current perspectives on parathyroid hormone (PTH) and PTH-related protein (PTHrP) as bone anabolic therapies

Biochemical pharmacology, 2013-05, Vol.85 (10), p.1417-1423

2013

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Osteocytes Acidify Their Microenvironment in Response to PTHrP In Vitro and in Lactating Mice In Vivo

Journal of bone and mineral research, 2017-08, Vol.32 (8), p.1761-1772

2017

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One Year of Abaloparatide, a Selective Activator of the PTH1 Receptor, Increased Bone Formation and Bone Mass in Osteopenic Ovariectomized Rats Without Increasing Bone Resorption

Journal of bone and mineral research, 2017-01, Vol.32 (1), p.24-33

2017

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Abaloparatide: A new pharmacological option for osteoporosis

American journal of health-system pharmacy, 2019-02, Vol.76 (3), p.130-135

2019

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miR-200b-3p/ERG/PTHrP axis mediates the inhibitory effect of ethanol on the differentiation of fetal cartilage into articular cartilage

Chemico-biological interactions, 2022-12, Vol.368, p.110201, Article 110201

2022

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Abaloparatide-SC improves trabecular microarchitecture as assessed by trabecular bone score (TBS): a 24-week randomized clinical trial

Osteoporosis international, 2018-02, Vol.29 (2), p.323-328

2018

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The Efficacy and Safety of Abaloparatide‐SC in Men With Osteoporosis: A Randomized Clinical Trial

Journal of bone and mineral research, 2022-12, Vol.37 (12), p.2435-2442

2022

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Effects of Abaloparatide on Bone Mineral Density in Proximal Femoral Regions Corresponding to Arthroplasty Gruen Zones: A Study of Postmenopausal Women with Osteoporosis

Journal of bone and joint surgery. American volume, 2024-07, Vol.106 (13), p.1162

2024

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Abaloparatide, a novel PTH receptor agonist, increased bone mass and strength in ovariectomized cynomolgus monkeys by increasing bone formation without increasing bone resorption

Osteoporosis international, 2018-03, Vol.29 (3), p.685-697

2018

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A comparison of parathyroid hormone‐related protein (1‐36) and parathyroid hormone (1‐34) on markers of bone turnover and bone density in postmenopausal women: The PrOP study

Journal of bone and mineral research, 2013-11, Vol.28 (11), p.2266-2276

2013

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Local injection of abaloparatide promotes mandibular condyle lengthening in adolescent rats via enhancing chondrogenesis and ossification

Journal of oral rehabilitation, 2024-02, Vol.51 (2), p.380-393

2024

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Abaloparatide increases bone mineral density and bone strength in ovariectomized rabbits with glucocorticoid-induced osteopenia

Osteoporosis international, 2019-08, Vol.30 (8), p.1607-1616

2019

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Abaloparatide is more potent than teriparatide in restoring bone mass and strength in type 1 diabetic male mice

Bone (New York, N.Y.), 2024-04, Vol.181, p.117042-117042, Article 117042

2024

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Bone mineral density response rates are greater in patients treated with abaloparatide compared with those treated with placebo or teriparatide: Results from the ACTIVE phase 3 trial

Bone (New York, N.Y.), 2019-03, Vol.120, p.137-140

2019

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Physiological and Pharmacological Roles of PTH and PTHrP in Bone Using Their Shared Receptor, PTH1R

Binding Selectivity of Abaloparatide for PTH-Type-1-Receptor Conformations and Effects on Downstream Signaling

Abaloparatide, the second generation osteoanabolic drug: Molecular mechanisms underlying its advantages over the first-in-class teriparatide

Abaloparatide: A review of preclinical and clinical studies

PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer

Effects of Abaloparatide, a Human Parathyroid Hormone-Related Peptide Analog, on Bone Mineral Density in Postmenopausal Women with Osteoporosis

Acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals

Regulation of WNT5A and WNT11 during MSC in vitro chondrogenesis: WNT inhibition lowers BMP and hedgehog activity, and reduces hypertrophy

Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1

Precisely Controlled Delivery of Abaloparatide through Injectable Hydrogel to Promote Bone Regeneration

Abaloparatide: First Global Approval

Current perspectives on parathyroid hormone (PTH) and PTH-related protein (PTHrP) as bone anabolic therapies

Osteocytes Acidify Their Microenvironment in Response to PTHrP In Vitro and in Lactating Mice In Vivo

One Year of Abaloparatide, a Selective Activator of the PTH1 Receptor, Increased Bone Formation and Bone Mass in Osteopenic Ovariectomized Rats Without Increasing Bone Resorption

Abaloparatide: A new pharmacological option for osteoporosis

miR-200b-3p/ERG/PTHrP axis mediates the inhibitory effect of ethanol on the differentiation of fetal cartilage into articular cartilage

Abaloparatide-SC improves trabecular microarchitecture as assessed by trabecular bone score (TBS): a 24-week randomized clinical trial

The Efficacy and Safety of Abaloparatide‐SC in Men With Osteoporosis: A Randomized Clinical Trial

Effects of Abaloparatide on Bone Mineral Density in Proximal Femoral Regions Corresponding to Arthroplasty Gruen Zones: A Study of Postmenopausal Women with Osteoporosis

Abaloparatide, a novel PTH receptor agonist, increased bone mass and strength in ovariectomized cynomolgus monkeys by increasing bone formation without increasing bone resorption

A comparison of parathyroid hormone‐related protein (1‐36) and parathyroid hormone (1‐34) on markers of bone turnover and bone density in postmenopausal women: The PrOP study

Local injection of abaloparatide promotes mandibular condyle lengthening in adolescent rats via enhancing chondrogenesis and ossification

Abaloparatide increases bone mineral density and bone strength in ovariectomized rabbits with glucocorticoid-induced osteopenia

Abaloparatide is more potent than teriparatide in restoring bone mass and strength in type 1 diabetic male mice

Bone mineral density response rates are greater in patients treated with abaloparatide compared with those treated with placebo or teriparatide: Results from the ACTIVE phase 3 trial

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