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Hypoxia and TGF-β1 induced PLOD2 expression improve the migration and invasion of cervical cancer cells by promoting epithelial-to-mesenchymal transition (EMT) and focal adhesion formation

Cancer cell international, 2017-05, Vol.17 (1), p.54-54, Article 54

2017

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PLOD2 high expression associates with immune infiltration and facilitates cancer progression in osteosarcoma

Frontiers in oncology, 2022-10, Vol.12, p.980390-980390

2022

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Tumour-suppressive miRNA-26a-5p and miR-26b-5p inhibit cell aggressiveness by regulating PLOD2 in bladder cancer

British journal of cancer, 2016-07, Vol.115 (3), p.354-363

2016

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Adipose-derived stromal cells improve functional recovery after spinal cord injury through TGF-β1/Smad3/PLOD2 pathway activation

Aging (Albany, NY.), 2021-01, Vol.13 (3), p.4370-4387

2021

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Clinicopathological significances of PLOD2, epithelial–mesenchymal transition markers, and cancer stem cells in patients with esophageal squamous cell carcinoma

Medicine (Baltimore), 2022-08, Vol.101 (34), p.e30112-e30112

2022

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PLOD2 as a potential regulator of peritoneal dissemination in gastric cancer

International journal of cancer, 2018-09, Vol.143 (5), p.1202-1211

2018

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Silencing PLOD2 attenuates cancer stem cell-like characteristics and cisplatin-resistant through Integrin β1 in laryngeal cancer

Translational oncology, 2022-08, Vol.22, p.101460-101460, Article 101460

2022

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Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma

Oncotarget, 2017-06, Vol.8 (26), p.41947-41962

2017

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Circ-Plod2 destabilizes Mpo mRNA by binding to IGF2BP2 to promote osteogenic differentiation of bone marrow mesenchymal stem cells

European journal of pharmacology, 2023-12, Vol.961, p.176192-176192, Article 176192

2023

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KDM1A regulated the osteo/dentinogenic differentiation process of the stem cells of the apical papilla via binding with PLOD2

Cell proliferation, 2018-08, Vol.51 (4), p.e12459-n/a

2018

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PLOD2 in cancer research

Biomedicine & pharmacotherapy, 2017-06, Vol.90, p.670-676

2017

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DT-13 suppresses breast cancer metastasis by modulating PLOD2 in the adipocytes microenvironment

Phytomedicine (Stuttgart), 2019-06, Vol.59, p.152778-152778, Article 152778

2019

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tDCS Regulates ASBT-3-OxoLCA-PLOD2-PTEN Signaling Pathway to Confer Neuroprotection Following Rat Cerebral Ischemia-Reperfusion Injury

Molecular neurobiology, 2023-11, Vol.60 (11), p.6715-6730

2023

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Pan-Cancer Analyses Reveal Oncogenic and Immunological Role of PLOD2

Frontiers in genetics, 2022-05, Vol.13, p.864655-864655

2022

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A hierarchical network of hypoxia-inducible factor and SMAD proteins governs procollagen lysyl hydroxylase 2 induction by hypoxia and transforming growth factor β1

The Journal of biological chemistry, 2019-09, Vol.294 (39), p.14308-14318

2019

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Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes collagen cross-linking and ECM stiffening to induce liver fibrosis

Biochimica et biophysica acta. Molecular basis of disease, 2024-06, Vol.1870 (5), p.167205-167205, Article 167205

2024

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Loss of Type I Collagen Telopeptide Lysyl Hydroxylation Causes Musculoskeletal Abnormalities in a Zebrafish Model of Bruck Syndrome

Journal of bone and mineral research, 2016-11, Vol.31 (11), p.1930-1942

2016

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PLOD2 gene expression in infrapatellar fat pad is correlated with fat mass in obese patients with end-stage knee osteoarthritis

Osteoarthritis and cartilage open, 2024-06, Vol.6 (2), p.100469-100469, Article 100469

2024

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Dysregulation of PLOD2 Promotes Tumor Metastasis and Invasion in Hepatocellular Carcinoma

Journal of clinical and translational hepatology, 2023-10, Vol.11 (5), p.1094-1105

2023

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Case Report: Exome Sequencing Identified a Novel Compound Heterozygous Variation in PLOD2 Causing Bruck Syndrome Type 2

Frontiers in genetics, 2021-02, Vol.12, p.619948

2021

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Bruck Syndrome: Beyond the Obvious

Fetal diagnosis and therapy, 2023-02, Vol.49 (11-12), p.479-485

2023

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Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma

International journal of oncology, 2016-05, Vol.48 (5), p.1837-1846

2016

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Bruck syndrome in 13 new patients: Identification of five novel FKBP10 and PLOD2 variants and further expansion of the phenotypic spectrum

American journal of medical genetics. Part A, 2022-06, Vol.188 (6), p.1815-1825

2022

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Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Cell communication and signaling, 2018-12, Vol.16 (1), p.100-100, Article 100

2018

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Hypoxic stellate cells of pancreatic cancer stroma regulate extracellular matrix fiber organization and cancer cell motility

Cancer letters, 2016-03, Vol.372 (2), p.210-218

2016

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Hypoxia and TGF-β1 induced PLOD2 expression improve the migration and invasion of cervical cancer cells by promoting epithelial-to-mesenchymal transition (EMT) and focal adhesion formation

PLOD2 high expression associates with immune infiltration and facilitates cancer progression in osteosarcoma

Tumour-suppressive miRNA-26a-5p and miR-26b-5p inhibit cell aggressiveness by regulating PLOD2 in bladder cancer

Adipose-derived stromal cells improve functional recovery after spinal cord injury through TGF-β1/Smad3/PLOD2 pathway activation

Clinicopathological significances of PLOD2, epithelial–mesenchymal transition markers, and cancer stem cells in patients with esophageal squamous cell carcinoma

PLOD2 as a potential regulator of peritoneal dissemination in gastric cancer

Silencing PLOD2 attenuates cancer stem cell-like characteristics and cisplatin-resistant through Integrin β1 in laryngeal cancer

Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma

Circ-Plod2 destabilizes Mpo mRNA by binding to IGF2BP2 to promote osteogenic differentiation of bone marrow mesenchymal stem cells

KDM1A regulated the osteo/dentinogenic differentiation process of the stem cells of the apical papilla via binding with PLOD2

PLOD2 in cancer research

DT-13 suppresses breast cancer metastasis by modulating PLOD2 in the adipocytes microenvironment

tDCS Regulates ASBT-3-OxoLCA-PLOD2-PTEN Signaling Pathway to Confer Neuroprotection Following Rat Cerebral Ischemia-Reperfusion Injury

Pan-Cancer Analyses Reveal Oncogenic and Immunological Role of PLOD2

A hierarchical network of hypoxia-inducible factor and SMAD proteins governs procollagen lysyl hydroxylase 2 induction by hypoxia and transforming growth factor β1

Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes collagen cross-linking and ECM stiffening to induce liver fibrosis

Loss of Type I Collagen Telopeptide Lysyl Hydroxylation Causes Musculoskeletal Abnormalities in a Zebrafish Model of Bruck Syndrome

PLOD2 gene expression in infrapatellar fat pad is correlated with fat mass in obese patients with end-stage knee osteoarthritis

Dysregulation of PLOD2 Promotes Tumor Metastasis and Invasion in Hepatocellular Carcinoma

Case Report: Exome Sequencing Identified a Novel Compound Heterozygous Variation in PLOD2 Causing Bruck Syndrome Type 2

Bruck Syndrome: Beyond the Obvious

Regulation of the collagen cross-linking enzymes LOXL2 and PLOD2 by tumor-suppressive microRNA-26a/b in renal cell carcinoma

Bruck syndrome in 13 new patients: Identification of five novel FKBP10 and PLOD2 variants and further expansion of the phenotypic spectrum

Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Hypoxic stellate cells of pancreatic cancer stroma regulate extracellular matrix fiber organization and cancer cell motility

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