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Motif-dependent immune co-receptor interactome profiling by photoaffinity chemical proteomics

Cell chemical biology, 2022-06, Vol.29 (6), p.1024-1036.e5

2022

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cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity

Immunity (Cambridge, Mass.), 2023-06, Vol.56 (6), p.1187-1203.e12

2023

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IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

Oncoimmunology, 2012-12, Vol.1 (9), p.1460-1468

2012

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Structural Basis of Amino Pyrimidine Derivatives for Inhibitory Activity of PKC-θ: 3D-QSAR and Molecular Docking Studies

Molecular informatics, 2012-09, Vol.31 (9), p.659-668

2012

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Targeting early PKCθ‐dependent T‐cell infiltration of dystrophic muscle reduces disease severity in a mouse model of muscular dystrophy

The Journal of pathology, 2018-03, Vol.244 (3), p.323-333

2018

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Inhibition of PKC‐θ preserves cardiac function and reduces fibrosis in streptozotocin‐induced diabetic cardiomyopathy

British journal of pharmacology, 2014-06, Vol.171 (11), p.2913-2924

2014

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Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease

Stem cell research, 2019-03, Vol.35, p.101401-101401, Article 101401

2019

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Black Ginseng Extract Exerts Potentially Anti-Asthmatic Activity by Inhibiting the Protein Kinase Cθ-Mediated IL-4/STAT6 Signaling Pathway

International journal of molecular sciences, 2023-07, Vol.24 (15), p.11970

2023

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The protective effects of curcumin in cerebral ischemia and reperfusion injury through PKC-θ signaling

Cell cycle (Georgetown, Tex.), 2021-03, Vol.20 (5-6), p.550-560

2021

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Protein Kinase C Theta Modulates PCMT1 through hnRNPL to Regulate FOXP3 Stability in Regulatory T Cells

Molecular therapy, 2020-10, Vol.28 (10), p.2220-2236

2020

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PKC-Theta in Regulatory and Effector T-cell Functions

Frontiers in immunology, 2015-10, Vol.6, p.530-530

2015

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Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition

Frontiers in immunology, 2016-02, Vol.7, p.24-24

2016

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Bioactive staurosporine derivatives from the Streptomyces sp. NB-A13

Bioorganic chemistry, 2019-02, Vol.82, p.33-40

2019

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LKB1 isoform expression modulates T cell plasticity downstream of PKCθ and IL-6

Molecular immunology, 2023-05, Vol.157, p.129-141

2023

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Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice

Diabetologia, 2023-03, Vol.66 (3), p.567-578

2023

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Plant-derived cell-penetrating microprotein α-astratide aM1 targets Akt signaling and alleviates insulin resistance

Cellular and molecular life sciences : CMLS, 2023-10, Vol.80 (10), p.293-293, Article 293

2023

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Molecular modelling studies of tricyclic triazinone analogues as potential PKC-θ inhibitors through combined QSAR, molecular docking and molecular dynamics simulations techniques

Journal of the Taiwan Institute of Chemical Engineers, 2018-10, Vol.91, p.155-175

2018

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MAP4K3/GLK in autoimmune disease, cancer and aging

Journal of biomedical science, 2019-10, Vol.26 (1), p.82-82, Article 82

2019

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Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis

ACS medicinal chemistry letters, 2019-08, Vol.10 (8), p.1134-1139

2019

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Annexin A5 is essential for PKCθ translocation during T-cell activation

The Journal of biological chemistry, 2020-10, Vol.295 (41), p.14214-14221

2020

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DOG1 and PKC- are useful in the diagnosis of KIT-negative gastrointestinal stromal tumors

Modern pathology, 2011-06, Vol.24 (6), p.866-875

2011

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PROTEIN KINASE Cθ IN T CELL ACTIVATION

Annual review of immunology, 2002-04, Vol.20 (1), p.761-794

2002

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NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

Frontiers in immunology, 2014, Vol.5, p.249-249

2014

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PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells

Cancer letters, 2022-02, Vol.526, p.112-130

2022

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Cell-Penetrating Anti-Protein Kinase C Theta Antibodies Act Intracellularly to Generate Stable, Highly Suppressive Regulatory T Cells

Molecular therapy, 2020-09, Vol.28 (9), p.1987-2006

2020

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Motif-dependent immune co-receptor interactome profiling by photoaffinity chemical proteomics

cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

Structural Basis of Amino Pyrimidine Derivatives for Inhibitory Activity of PKC-θ: 3D-QSAR and Molecular Docking Studies

Targeting early PKCθ‐dependent T‐cell infiltration of dystrophic muscle reduces disease severity in a mouse model of muscular dystrophy

Inhibition of PKC‐θ preserves cardiac function and reduces fibrosis in streptozotocin‐induced diabetic cardiomyopathy

Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease

Black Ginseng Extract Exerts Potentially Anti-Asthmatic Activity by Inhibiting the Protein Kinase Cθ-Mediated IL-4/STAT6 Signaling Pathway

The protective effects of curcumin in cerebral ischemia and reperfusion injury through PKC-θ signaling

Protein Kinase C Theta Modulates PCMT1 through hnRNPL to Regulate FOXP3 Stability in Regulatory T Cells

PKC-Theta in Regulatory and Effector T-cell Functions

Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition

Bioactive staurosporine derivatives from the Streptomyces sp. NB-A13

LKB1 isoform expression modulates T cell plasticity downstream of PKCθ and IL-6

Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice

Plant-derived cell-penetrating microprotein α-astratide aM1 targets Akt signaling and alleviates insulin resistance

Molecular modelling studies of tricyclic triazinone analogues as potential PKC-θ inhibitors through combined QSAR, molecular docking and molecular dynamics simulations techniques

MAP4K3/GLK in autoimmune disease, cancer and aging

Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis

Annexin A5 is essential for PKCθ translocation during T-cell activation

DOG1 and PKC- are useful in the diagnosis of KIT-negative gastrointestinal stromal tumors

PROTEIN KINASE Cθ IN T CELL ACTIVATION

NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome

PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells

Cell-Penetrating Anti-Protein Kinase C Theta Antibodies Act Intracellularly to Generate Stable, Highly Suppressive Regulatory T Cells

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