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Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy

Journal of lipid research, 2020-05, Vol.61 (5), p.611-635

2020

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ENAH transcriptionally activated by YY1 promotes growth and invasion of laryngocarcinoma cells through PI3K/AKT signaling

European journal of pharmacology, 2024-11, Vol.983, p.176991, Article 176991

2024

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Curcumin alleviates oxidative stress and inhibits apoptosis in diabetic cardiomyopathy via Sirt1‐Foxo1 and PI3K‐Akt signalling pathways

Journal of cellular and molecular medicine, 2020-11, Vol.24 (21), p.12355-12367

2020

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Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3k‐Akt signaling pathway

Journal of cellular biochemistry, 2018-06, Vol.119 (6), p.4420-4434

2018

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Conserved insulin signaling in the regulation of oocyte growth, development, and maturation

Molecular reproduction and development, 2017-06, Vol.84 (6), p.444-459

2017

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Cardamonin inhibits silicosis development through the PI3K-AKT signaling pathway

Ecotoxicology and environmental safety, 2024-10, Vol.285, p.117067, Article 117067

2024

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MiR-125b-5p suppresses the bladder cancer progression via targeting HK2 and suppressing PI3K/AKT pathway

Human cell : official journal of Human Cell Research Society, 2020-01, Vol.33 (1), p.185-194

2020

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Sodium butyrate attenuated neuronal apoptosis via GPR41/Gβγ/PI3K/Akt pathway after MCAO in rats

Journal of cerebral blood flow and metabolism, 2021-02, Vol.41 (2), p.267-281

2021

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PI3K/Akt/mTOR Pathway and Its Role in Cancer Therapeutics: Are We Making Headway?

Frontiers in oncology, 2022-03, Vol.12, p.819128

2022

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Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer

Seminars in cancer biology, 2022-10, Vol.85, p.69-94

2022

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Inhibition of human glioblastoma multiforme cells by 10,11-dehydrocurvularin through the MMP-2 and PI3K/AKT signaling pathways

European journal of pharmacology, 2022-12, Vol.936, p.175348-175348, Article 175348

2022

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The PI3K AKT Pathway as a Target for Cancer Treatment

Annual review of medicine, 2016-01, Vol.67 (1), p.11-28

2016

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The mechanism of miR-665 targeting GNB3 in aluminum-induced neuronal apoptosis

Journal of trace elements in medicine and biology, 2024-09, Vol.85, p.127488, Article 127488

2024

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Avermectin induces carp neurotoxicity by mediating blood-brain barrier dysfunction, oxidative stress, inflammation, and apoptosis through PI3K/Akt and NF-κB pathways

Ecotoxicology and environmental safety, 2022-09, Vol.243, p.113961-113961, Article 113961

2022

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PI3K regulates the activation of NLRP3 inflammasome in atherosclerosis through part-dependent AKT signaling pathway

Experimental Animals, 2021, pp.21-0002

2021

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BPA and low-Se exacerbate apoptosis and mitophagy in chicken pancreatic cells by regulating the PTEN/PI3K/AKT/mTOR pathway

Journal of advanced research, 2024-02

2024

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STC2 knockdown inhibits cell proliferation and glycolysis in hepatocellular carcinoma through promoting autophagy by PI3K/Akt/mTOR pathway

Archives of biochemistry and biophysics, 2024-11, Vol.761, p.110149, Article 110149

2024

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The role of β2-AR/PI3K/AKT pathway in the proliferation, migration and invasion of THLE-2 cells induced by nicotine

Toxicology (Amsterdam), 2024-11, Vol.508, p.153924, Article 153924

2024

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New emerging roles of CD133 in cancer stem cell: Signaling pathway and miRNA regulation

Journal of cellular physiology, 2019-12, Vol.234 (12), p.21642-21661

2019

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PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer

Biochemical pharmacology, 2020-02, Vol.172, p.113729-113729, Article 113729

2020

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Rab GTPases: Emerging Oncogenes and Tumor Suppressive Regulators for the Editing of Survival Pathways in Cancer

Cancers, 2020-01, Vol.12 (2), p.259

2020

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Lycorine relieves the CCl4-induced liver fibrosis mainly via the JAK2/STAT3 and PI3K/AKT signaling pathways

Toxicology and applied pharmacology, 2024-08, Vol.489, p.117017, Article 117017

2024

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Circ_0007624 suppresses the development of esophageal squamous cell carcinoma via targeting miR-224-5p/CPEB3 to inactivate the EGFR/PI3K/AKT signaling

Cellular signalling, 2022-11, Vol.99, p.110448-110448, Article 110448

2022

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Insulin-Like Growth Factor-1 Promotes G1/S Cell Cycle Progression through Bidirectional Regulation of Cyclins and Cyclin-Dependent Kinase Inhibitors via the Phosphatidylinositol 3-Kinase/Akt Pathway in Developing Rat Cerebral Cortex

The Journal of neuroscience, 2009-01, Vol.29 (3), p.775-788

2009

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CD133: beyond a cancer stem cell biomarker

Journal of drug targeting, 2019-03, Vol.27 (3), p.257-269

2019

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Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy

ENAH transcriptionally activated by YY1 promotes growth and invasion of laryngocarcinoma cells through PI3K/AKT signaling

Curcumin alleviates oxidative stress and inhibits apoptosis in diabetic cardiomyopathy via Sirt1‐Foxo1 and PI3K‐Akt signalling pathways

Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3k‐Akt signaling pathway

Conserved insulin signaling in the regulation of oocyte growth, development, and maturation

Cardamonin inhibits silicosis development through the PI3K-AKT signaling pathway

MiR-125b-5p suppresses the bladder cancer progression via targeting HK2 and suppressing PI3K/AKT pathway

Sodium butyrate attenuated neuronal apoptosis via GPR41/Gβγ/PI3K/Akt pathway after MCAO in rats

PI3K/Akt/mTOR Pathway and Its Role in Cancer Therapeutics: Are We Making Headway?

Attacking the PI3K/Akt/mTOR signaling pathway for targeted therapeutic treatment in human cancer

Inhibition of human glioblastoma multiforme cells by 10,11-dehydrocurvularin through the MMP-2 and PI3K/AKT signaling pathways

The PI3K AKT Pathway as a Target for Cancer Treatment

The mechanism of miR-665 targeting GNB3 in aluminum-induced neuronal apoptosis

Avermectin induces carp neurotoxicity by mediating blood-brain barrier dysfunction, oxidative stress, inflammation, and apoptosis through PI3K/Akt and NF-κB pathways

PI3K regulates the activation of NLRP3 inflammasome in atherosclerosis through part-dependent AKT signaling pathway

BPA and low-Se exacerbate apoptosis and mitophagy in chicken pancreatic cells by regulating the PTEN/PI3K/AKT/mTOR pathway

STC2 knockdown inhibits cell proliferation and glycolysis in hepatocellular carcinoma through promoting autophagy by PI3K/Akt/mTOR pathway

The role of β2-AR/PI3K/AKT pathway in the proliferation, migration and invasion of THLE-2 cells induced by nicotine

New emerging roles of CD133 in cancer stem cell: Signaling pathway and miRNA regulation

PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer

Rab GTPases: Emerging Oncogenes and Tumor Suppressive Regulators for the Editing of Survival Pathways in Cancer

Lycorine relieves the CCl4-induced liver fibrosis mainly via the JAK2/STAT3 and PI3K/AKT signaling pathways

Circ_0007624 suppresses the development of esophageal squamous cell carcinoma via targeting miR-224-5p/CPEB3 to inactivate the EGFR/PI3K/AKT signaling

Insulin-Like Growth Factor-1 Promotes G1/S Cell Cycle Progression through Bidirectional Regulation of Cyclins and Cyclin-Dependent Kinase Inhibitors via the Phosphatidylinositol 3-Kinase/Akt Pathway in Developing Rat Cerebral Cortex

CD133: beyond a cancer stem cell biomarker

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