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Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3k‐Akt signaling pathway

Journal of cellular biochemistry, 2018-06, Vol.119 (6), p.4420-4434

2018

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Thidiazuron suppresses breast cancer via targeting miR-132 and dysregulation of the PI3K–Akt signaling pathway mediated by the miR-202-5p–PTEN axis

Biochemistry and cell biology, 2021-05, Vol.99 (3), p.374-384

2021

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A novel PLS1 c.981+1G>A variant causes autosomal‐dominant hereditary hearing loss in a family

Clinical genetics, 2023-04, Vol.103 (4), p.413-423

2023

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Bruceine A inhibited breast cancer proliferation and metastasis by inducing autophagy via targeting PI3K‐AKT signaling pathway

Chemical biology & drug design, 2024-01, Vol.103 (1), p.e14398-n/a

2024

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The whole transcriptional profiling of cellular metabolism during adipogenesis from hMSCs

Journal of cellular physiology, 2020-01, Vol.235 (1), p.349-363

2020

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Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury

Neural regeneration research, 2022-05, Vol.17 (5), p.1080-1087

2022

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Integrating network pharmacology and experimental verification to investigate the pharmacological mechanisms of Buzhong Yiqi decoction in the treatment of non‐small cell lung cancer

Chemical biology & drug design, 2024-01, Vol.103 (1), p.e14414-n/a

2024

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Anti‐rheumatoid arthritis effects of Xanthii Fructus by affecting the PI3K‐AKT signaling pathway based on TMT‐labeled quantitative proteomics

Biomedical chromatography, 2023-01, Vol.37 (1), p.e5520-n/a

2023

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Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway

International journal of molecular medicine, 2016-10, Vol.38 (4), p.1179-1189

2016

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Network Pharmacology and Experimental Evidence: PI3K/AKT Signaling Pathway is Involved in the Antidepressive Roles of Chaihu Shugan San

Drug design, development and therapy, 2021-01, Vol.15, p.3425-3441

2021

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Qishen Huanwu capsule reduces pirarubicin-induced cardiotoxicity in rats by activating the PI3K/Akt/mTOR pathway

Annals of palliative medicine, 2020-09, Vol.9 (5), p.3453-3461

2020

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Prostate cancer small extracellular vesicles participate in androgen-independent transformation of prostate cancer by transferring let-7a-5p

Heliyon, 2022-12, Vol.8 (12), p.e12114-e12114, Article e12114

2022

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Transcriptomic‐based toxicological investigations of ethanol to human umbilical vein endothelial cells

Journal of applied toxicology, 2021-05, Vol.41 (5), p.736-744

2021

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Mutations in TOP2B cause autosomal‐dominant hereditary hearing loss via inhibition of the PI3K‐Akt signalling pathway

FEBS letters, 2019-08, Vol.593 (15), p.2008-2018

2019

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MiR-30a-5p Overexpression May Overcome EGFR-Inhibitor Resistance through Regulating PI3K/AKT Signaling Pathway in Non-small Cell Lung Cancer Cell Lines

Frontiers in genetics, 2016-11, Vol.7, p.197-197

2016

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Gene mutations in the PI3K/Akt signaling pathway were related to immune thrombocytopenia pathogenesis

Medicine (Baltimore), 2023-02, Vol.102 (7), p.e32947-e32947

2023

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Cytoprotective Effects Evaluation of a Novel Danshensu Derivative DEX-018 against Oxidative Stress Injury in HUVECs

Biological and Pharmaceutical Bulletin, 2020/05/01, Vol.43(5), pp.801-809

2020

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Effects of Glut1 gene silencing on proliferation, differentiation, and apoptosis of colorectal cancer cells by targeting the TGF‐β/PI3K‐AKT‐mTOR signaling pathway

Journal of cellular biochemistry, 2018-02, Vol.119 (2), p.2356-2367

2018

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ZNF191 alters DNA methylation and activates the PI3K‐AKT pathway in hepatoma cells via transcriptional regulation of DNMT1

Cancer medicine (Malden, MA), 2022-03, Vol.11 (5), p.1269-1280

2022

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LncRNA RHPN1‐AS1 inhibition induces autophagy and apoptosis in prostate cancer cells via the miR‐7‐5p/EGFR/PI3K/AKT/mTOR signaling pathway

Environmental toxicology, 2022-12, Vol.37 (12), p.3013-3027

2022

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The Chinese Herb Codonopsis pilosula Isolate Isorhapontigenin protects against oxidative stress injury by inhibiting the activation of PI3K/Akt signaling pathway

Journal of integrative neuroscience, 2020-06, Vol.19 (2), p.333-340

2020

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Identification of potential molecular mechanism related to craniofacial dysmorphism caused by FOXI3 deficiency

Molecular genetics & genomic medicine, 2024-03, Vol.12 (3), p.e2411-n/a

2024

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Hypoglycemic and hypolipidemic effects of total saponins from Stauntonia chinensis in diabetic db/db mice

Journal of cellular and molecular medicine, 2018-12, Vol.22 (12), p.6026-6038

2018

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MiR-138 suppresses airway smooth muscle cell proliferation through the PI3K/AKT signaling pathway by targeting PDK1

Experimental lung research, 2015-08, Vol.41 (7), p.363-369

2015

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Response of the PI3K‐AKT signalling pathway to low salinity and the effect of its inhibition mediated by wortmannin on ion channels in turbot Scophthalmus maximus

Aquaculture research, 2020-07, Vol.51 (7), p.2676-2686

2020

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Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3k‐Akt signaling pathway

Thidiazuron suppresses breast cancer via targeting miR-132 and dysregulation of the PI3K–Akt signaling pathway mediated by the miR-202-5p–PTEN axis

A novel PLS1 c.981+1G>A variant causes autosomal‐dominant hereditary hearing loss in a family

Bruceine A inhibited breast cancer proliferation and metastasis by inducing autophagy via targeting PI3K‐AKT signaling pathway

The whole transcriptional profiling of cellular metabolism during adipogenesis from hMSCs

Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury

Integrating network pharmacology and experimental verification to investigate the pharmacological mechanisms of Buzhong Yiqi decoction in the treatment of non‐small cell lung cancer

Anti‐rheumatoid arthritis effects of Xanthii Fructus by affecting the PI3K‐AKT signaling pathway based on TMT‐labeled quantitative proteomics

Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway

Network Pharmacology and Experimental Evidence: PI3K/AKT Signaling Pathway is Involved in the Antidepressive Roles of Chaihu Shugan San

Qishen Huanwu capsule reduces pirarubicin-induced cardiotoxicity in rats by activating the PI3K/Akt/mTOR pathway

Prostate cancer small extracellular vesicles participate in androgen-independent transformation of prostate cancer by transferring let-7a-5p

Transcriptomic‐based toxicological investigations of ethanol to human umbilical vein endothelial cells

Mutations in TOP2B cause autosomal‐dominant hereditary hearing loss via inhibition of the PI3K‐Akt signalling pathway

MiR-30a-5p Overexpression May Overcome EGFR-Inhibitor Resistance through Regulating PI3K/AKT Signaling Pathway in Non-small Cell Lung Cancer Cell Lines

Gene mutations in the PI3K/Akt signaling pathway were related to immune thrombocytopenia pathogenesis

Cytoprotective Effects Evaluation of a Novel Danshensu Derivative DEX-018 against Oxidative Stress Injury in HUVECs

Effects of Glut1 gene silencing on proliferation, differentiation, and apoptosis of colorectal cancer cells by targeting the TGF‐β/PI3K‐AKT‐mTOR signaling pathway

ZNF191 alters DNA methylation and activates the PI3K‐AKT pathway in hepatoma cells via transcriptional regulation of DNMT1

LncRNA RHPN1‐AS1 inhibition induces autophagy and apoptosis in prostate cancer cells via the miR‐7‐5p/EGFR/PI3K/AKT/mTOR signaling pathway

The Chinese Herb Codonopsis pilosula Isolate Isorhapontigenin protects against oxidative stress injury by inhibiting the activation of PI3K/Akt signaling pathway

Identification of potential molecular mechanism related to craniofacial dysmorphism caused by FOXI3 deficiency

Hypoglycemic and hypolipidemic effects of total saponins from Stauntonia chinensis in diabetic db/db mice

MiR-138 suppresses airway smooth muscle cell proliferation through the PI3K/AKT signaling pathway by targeting PDK1

Response of the PI3K‐AKT signalling pathway to low salinity and the effect of its inhibition mediated by wortmannin on ion channels in turbot Scophthalmus maximus

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