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TREM1 induces microglial ferroptosis through the PERK pathway in diabetic-associated cognitive impairment

Experimental neurology, 2025-01, Vol.383, p.115031, Article 115031

2025

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Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

Cell metabolism, 2019-12, Vol.30 (6), p.1141-1151.e5

2019

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FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury

Cell reports (Cambridge), 2018-09, Vol.24 (11), p.2985-2999

2018

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Ethnic Variation and Structure‐Function Analysis of Tauopathy‐Associated PERK Alleles

Israel journal of chemistry, 2024-05

2024

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The Unfolded Protein Response and Cell Fate Control

Molecular cell, 2018-01, Vol.69 (2), p.169-181

2018

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Overexpressed PERK suppresses the neurodegenerative phenotypes in PINK1B9 flies by enhancing mitochondrial function

Neurochemistry international, 2020-11, Vol.140, p.104825-104825, Article 104825

2020

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Seneca valley virus activates autophagy through the PERK and ATF6 UPR pathways

Virology (New York, N.Y.), 2019-11, Vol.537, p.254-263

2019

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Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer

Cell, 2017-02, Vol.168 (4), p.692-706

2017

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Japanese Encephalitis Virus Induces Apoptosis and Encephalitis by Activating the PERK Pathway

Journal of virology, 2019-09, Vol.93 (17)

2019

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PAT exposure caused human hepatocytes apoptosis and induced mice subacute liver injury by activating oxidative stress and the ERS-associated PERK pathway

The Science of the total environment, 2024-10, Vol.955, p.177003, Article 177003

2024

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Reshaping endoplasmic reticulum quality control through the unfolded protein response

Molecular cell, 2022-04, Vol.82 (8), p.1477-1491

2022

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Repurposing Aprepitant: Can it protect against doxorubicin-induced Chemobrain beyond its antiemetic role?

Life sciences (1973), 2024-12, Vol.359, p.123210, Article 123210

2024

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MicroRNA-15b promotes cardiac ischemia injury by the inhibition of Mitofusin 2/PERK pathway

Biochemical pharmacology, 2024-08, Vol.226, p.116372, Article 116372

2024

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Evolution of the unfolded protein response in plants

Plant, cell and environment, 2021-08, Vol.44 (8), p.2625-2635

Howell, Stephen H.

2021

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CCT020312 exerts anti-prostate cancer effect by inducing G1 cell cycle arrest, apoptosis and autophagy through activation of PERK/eIF2α/ATF4/CHOP signaling

Biochemical pharmacology, 2024-03, Vol.221, p.116038, Article 116038

2024

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CHIP suppresses the proliferation and migration of A549 cells by mediating the ubiquitination of eIF2α and upregulation of tumor suppressor RBM5

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.105673-105673, Article 105673

2024

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Protein folding dependence on selenoprotein M contributes to steady cartilage extracellular matrix repressing ferroptosis via PERK/ATF4/CHAC1 axis

Osteoarthritis and cartilage, 2024-10

2024

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Arsenic induces ferroptosis and acute lung injury through mtROS-mediated mitochondria-associated endoplasmic reticulum membrane dysfunction

Ecotoxicology and environmental safety, 2022-06, Vol.238, p.113595-113595, Article 113595

2022

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Inside Cover: Phenotypic Discovery of Neuroprotective Agents by Regulation of Tau Proteostasis via Stress‐Responsive Activation of PERK Signaling (Angew. Chem. Int. Ed. 4/2021)

Angewandte Chemie International Edition, 2021-01, Vol.60 (4), p.1662-1662

2021

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Air pollution and perk consumption

International review of financial analysis, 2024-11, Vol.96, p.103688, Article 103688

2024

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Foot-and-mouth disease virus induces PERK mediated autophagy to suppress antiviral interferon response

Journal of cell science, 2020-01, Vol.134 (5)

2020

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Curcumin/Liposome Nanotechnology as Delivery Platform for Anti-inflammatory Activities via NFkB/ERK/pERK Pathway in Human Dental Pulp Treated With 2-HydroxyEthyl MethAcrylate (HEMA)

Frontiers in physiology, 2019-06, Vol.10, p.633-633

2019

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ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress

Cancers, 2020-03, Vol.12 (3), p.569

2020

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FXR Inhibits NLRP3 Inflammasome Activation by ER Stress

The FASEB journal, 2018-04, Vol.32 (S1), p.533.2-533.2

2018

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Berberine ameliorates lipopolysaccharide‐induced acute lung injury via the PERK‐mediated Nrf2/HO‐1 signaling axis

Phytotherapy research, 2019-01, Vol.33 (1), p.130-148

2019

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TREM1 induces microglial ferroptosis through the PERK pathway in diabetic-associated cognitive impairment

Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury

Ethnic Variation and Structure‐Function Analysis of Tauopathy‐Associated PERK Alleles

The Unfolded Protein Response and Cell Fate Control

Overexpressed PERK suppresses the neurodegenerative phenotypes in PINK1B9 flies by enhancing mitochondrial function

Seneca valley virus activates autophagy through the PERK and ATF6 UPR pathways

Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer

Japanese Encephalitis Virus Induces Apoptosis and Encephalitis by Activating the PERK Pathway

PAT exposure caused human hepatocytes apoptosis and induced mice subacute liver injury by activating oxidative stress and the ERS-associated PERK pathway

Reshaping endoplasmic reticulum quality control through the unfolded protein response

Repurposing Aprepitant: Can it protect against doxorubicin-induced Chemobrain beyond its antiemetic role?

MicroRNA-15b promotes cardiac ischemia injury by the inhibition of Mitofusin 2/PERK pathway

Evolution of the unfolded protein response in plants

CCT020312 exerts anti-prostate cancer effect by inducing G1 cell cycle arrest, apoptosis and autophagy through activation of PERK/eIF2α/ATF4/CHOP signaling

CHIP suppresses the proliferation and migration of A549 cells by mediating the ubiquitination of eIF2α and upregulation of tumor suppressor RBM5

Protein folding dependence on selenoprotein M contributes to steady cartilage extracellular matrix repressing ferroptosis via PERK/ATF4/CHAC1 axis

Arsenic induces ferroptosis and acute lung injury through mtROS-mediated mitochondria-associated endoplasmic reticulum membrane dysfunction

Inside Cover: Phenotypic Discovery of Neuroprotective Agents by Regulation of Tau Proteostasis via Stress‐Responsive Activation of PERK Signaling (Angew. Chem. Int. Ed. 4/2021)

Air pollution and perk consumption

Foot-and-mouth disease virus induces PERK mediated autophagy to suppress antiviral interferon response

Curcumin/Liposome Nanotechnology as Delivery Platform for Anti-inflammatory Activities via NFkB/ERK/pERK Pathway in Human Dental Pulp Treated With 2-HydroxyEthyl MethAcrylate (HEMA)

ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress

FXR Inhibits NLRP3 Inflammasome Activation by ER Stress

Berberine ameliorates lipopolysaccharide‐induced acute lung injury via the PERK‐mediated Nrf2/HO‐1 signaling axis

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