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P2Y12 receptors: structure and function

Journal of thrombosis and haemostasis, 2015-06, Vol.13 (S1), p.S10-S16

Cattaneo, M.

2015

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Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice

Nature communications, 2021-09, Vol.12 (1), p.5289-5289, Article 5289

2021

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Neuronal hyperactivity recruits microglial processes via neuronal NMDA receptors and microglial P2Y12 receptors after status epilepticus

The Journal of neuroscience, 2014-08, Vol.34 (32), p.10528-10540

2014

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Microglial P2Y12 receptors regulate microglial activation and surveillance during neuropathic pain

Brain, behavior, and immunity, 2016-07, Vol.55, p.82-92

2016

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Modulation of microglial process convergence toward neuronal dendrites by extracellular calcium

The Journal of neuroscience, 2015-02, Vol.35 (6), p.2417-2422

2015

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Falta de adherencia a ticagrelor frente a clopidogrel y riesgo de eventos en pacientes con SCA. Resultados del registro CREA-ARIAM

Revista española de cardiologia, 2024-02, Vol.77 (2), p.113-124

2024

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P2Y12 Receptor Modulates Sepsis-Induced Inflammation

Arteriosclerosis, thrombosis, and vascular biology, 2016-05, Vol.36 (5), p.961

2016

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Central P2Y12 receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents

Neurobiology of disease, 2014-10, Vol.70, p.162-178

2014

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The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling

The Journal of clinical investigation, 2012-10, Vol.122 (10), p.3579-3592

2012

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The platelet P2Y12 receptor for adenosine diphosphate: congenital and drug-induced defects

Blood, 2011-02, Vol.117 (7), p.2102-2112

Cattaneo, Marco

2011

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Protease-activated receptor-4 and purinergic receptor P2Y12 dimerize, co-internalize, and activate Akt signaling via endosomal recruitment of β-arrestin

The Journal of biological chemistry, 2017-08, Vol.292 (33), p.13867-13878

2017

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P2Y(12) receptors in platelets and other hematopoietic and non-hematopoietic cells

Purinergic signalling, 2012-09, Vol.8 (3), p.609-619

Gachet, Christian

2012

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P2Y12 shRNA treatment decreases SGC activation to relieve diabetic neuropathic pain in type 2 diabetes mellitus rats

Journal of cellular physiology, 2018-12, Vol.233 (12), p.9620-9628

2018

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Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12‐receptor

Journal of thrombosis and haemostasis, 2014-11, Vol.12 (11), p.1898-1905

2014

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Platelet P2Y12 is involved in murine pulmonary metastasis

PloS one, 2013-11, Vol.8 (11), p.e80780-e80780

2013

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Purinergic Receptor P2Y12-Mediated Tau Internalization in Microglia

Methods in molecular biology (Clifton, N.J.), 2024, Vol.2754, p.457

2024

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P2Y12 Receptor Localizes in the Renal Collecting Duct and Its Blockade Augments Arginine Vasopressin Action and Alleviates Nephrogenic Diabetes Insipidus

Journal of the American Society of Nephrology, 2015-12, Vol.26 (12), p.2978-2987

2015

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Relationship between post‐treatment platelet reactivity and ischemic and bleeding events at 1‐year follow‐up in patients receiving prasugrel

Journal of thrombosis and haemostasis, 2012-10, Vol.10 (10), p.1999-2005

2012

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Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures

Cell reports (Cambridge), 2020-11, Vol.33 (5), p.108346-108346, Article 108346

2020

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Interaction of Tau with G-Protein-Coupled Purinergic P2Y12 Receptor by Molecular Docking and Molecular Dynamic Simulation

Methods in molecular biology (Clifton, N.J.), 2024, Vol.2754, p.33

2024

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Arrestin Scaffolds NHERF1 to the P2Y12 Receptor to Regulate Receptor Internalization

The Journal of biological chemistry, 2012-07, Vol.287 (29), p.24505-24515

2012

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Exploration of efficacy and bleeding with combined phosphoinositide 3‐kinase β inhibition and aspirin in man

Journal of thrombosis and haemostasis, 2015-08, Vol.13 (8), p.1494-1502

2015

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Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points—Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC)

The American heart journal, 2018-04, Vol.198, p.152-159

2018

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Nonadherence to ticagrelor versus clopidogrel and clinical outcomes in patients with ACS. Results from the CREA-ARIAM registry

Revista española de cardiología (English ed.), 2024-02, Vol.77 (2), p.113-124

2024

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Ticagrelor reverses the mitochondrial dysfunction through preventing accumulated autophagosomes-dependent apoptosis and ER stress in insulin-resistant H9c2 myocytes

Molecular and cellular biochemistry, 2020-06, Vol.469 (1-2), p.97-107

2020

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P2Y12 receptors: structure and function

Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice

Neuronal hyperactivity recruits microglial processes via neuronal NMDA receptors and microglial P2Y12 receptors after status epilepticus

Microglial P2Y12 receptors regulate microglial activation and surveillance during neuropathic pain

Modulation of microglial process convergence toward neuronal dendrites by extracellular calcium

Falta de adherencia a ticagrelor frente a clopidogrel y riesgo de eventos en pacientes con SCA. Resultados del registro CREA-ARIAM

P2Y12 Receptor Modulates Sepsis-Induced Inflammation

Central P2Y12 receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents

The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling

The platelet P2Y12 receptor for adenosine diphosphate: congenital and drug-induced defects

Protease-activated receptor-4 and purinergic receptor P2Y12 dimerize, co-internalize, and activate Akt signaling via endosomal recruitment of β-arrestin

P2Y(12) receptors in platelets and other hematopoietic and non-hematopoietic cells

P2Y12 shRNA treatment decreases SGC activation to relieve diabetic neuropathic pain in type 2 diabetes mellitus rats

Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12‐receptor

Platelet P2Y12 is involved in murine pulmonary metastasis

Purinergic Receptor P2Y12-Mediated Tau Internalization in Microglia

P2Y12 Receptor Localizes in the Renal Collecting Duct and Its Blockade Augments Arginine Vasopressin Action and Alleviates Nephrogenic Diabetes Insipidus

Relationship between post‐treatment platelet reactivity and ischemic and bleeding events at 1‐year follow‐up in patients receiving prasugrel

Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures

Interaction of Tau with G-Protein-Coupled Purinergic P2Y12 Receptor by Molecular Docking and Molecular Dynamic Simulation

Arrestin Scaffolds NHERF1 to the P2Y12 Receptor to Regulate Receptor Internalization

Exploration of efficacy and bleeding with combined phosphoinositide 3‐kinase β inhibition and aspirin in man

Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points—Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC)

Nonadherence to ticagrelor versus clopidogrel and clinical outcomes in patients with ACS. Results from the CREA-ARIAM registry

Ticagrelor reverses the mitochondrial dysfunction through preventing accumulated autophagosomes-dependent apoptosis and ER stress in insulin-resistant H9c2 myocytes

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