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Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

The New England journal of medicine, 2017-09, Vol.377 (13), p.1217-1227

2017

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Linezolid for Treatment of Chronic Extensively Drug-Resistant Tuberculosis

The New England journal of medicine, 2012-10, Vol.367 (16), p.1508-1518

2012

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Once-Weekly Dalbavancin versus Daily Conventional Therapy for Skin Infection

The New England journal of medicine, 2014-06, Vol.370 (23), p.2169-2179

2014

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Linezolid in Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia: A Randomized, Controlled Study

Clinical infectious diseases, 2012-03, Vol.54 (5), p.621-629

2012

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Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9316-9339

2020

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Clinical Population Pharmacokinetics and Toxicodynamics of Linezolid

Antimicrobial agents and chemotherapy, 2014-04, Vol.58 (4), p.2334-2343

2014

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Nonclinical and pharmacokinetic assessments to evaluate the potential of tedizolid and linezolid to affect mitochondrial function

Antimicrobial agents and chemotherapy, 2015-01, Vol.59 (1), p.178-185

2015

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Tedizolid population pharmacokinetics, exposure response, and target attainment

Antimicrobial agents and chemotherapy, 2014-11, Vol.58 (11), p.6462-6470

2014

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Safety of Anacetrapib in Patients with or at High Risk for Coronary Heart Disease

The New England journal of medicine, 2010-12, Vol.363 (25), p.2406-2415

2010

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High plasma linezolid concentration and impaired renal function affect development of linezolid-induced thrombocytopenia

Journal of antimicrobial chemotherapy, 2013-09, Vol.68 (9), p.2128-2133

2013

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Analysis of thrombocytopenic effects and population pharmacokinetics of linezolid: a dosage strategy according to the trough concentration target and renal function in adult patients

International journal of antimicrobial agents, 2014-09, Vol.44 (3), p.242-247

2014

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Which trial do we need? Empiric Glycopeptides plus clindamycin versus Oxazolidinones for suspected toxic shock and necrotizing soft tissue infections

Clinical microbiology and infection, 2024-05, Vol.30 (5), p.570-573

2024

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Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

The Lancet (British edition), 2008-12, Vol.372 (9656), p.2115-2123

2008

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New Potent Antibacterial Oxazolidinone (MRX-I) with an Improved Class Safety Profile

Journal of medicinal chemistry, 2014-06, Vol.57 (11), p.4487-4497

2014

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A phase I study of the safety, tolerability, and pharmacokinetics of contezolid acefosamil after intravenous and oral administration in healthy Chinese subjects

Antimicrobial agents and chemotherapy, 2023-11, Vol.67 (11), p.e0079623-e0079623

2023

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Therapeutic drug monitoring may improve safety outcomes of long-term treatment with linezolid in adult patients

Journal of antimicrobial chemotherapy, 2012-08, Vol.67 (8), p.2034-2042

2012

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Larger Vancomycin Doses (at Least Four Grams per Day) Are Associated with an Increased Incidence of Nephrotoxicity

Antimicrobial Agents and Chemotherapy, 2008-04, Vol.52 (4), p.1330-1336

2008

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Biomarker-Assisted Dose Selection for Safety and Efficacy in Early Development of PNU-100480 for Tuberculosis

Antimicrobial Agents and Chemotherapy, 2011-02, Vol.55 (2), p.567-574

2011

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Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trials

The Lancet infectious diseases, 2019-03, Vol.19 (3), p.265-274

2019

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Safety, tolerability and pharmacokinetics of 21 day multiple oral administration of a new oxazolidinone antibiotic, LCB01-0371, in healthy male subjects

Journal of antimicrobial chemotherapy, 2018-01, Vol.73 (1), p.183-190

2018

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A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections

Journal of antimicrobial chemotherapy, 2022-05, Vol.77 (6), p.1762-1769

2022

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Tolerability and Pharmacokinetics of Contezolid at Therapeutic and Supratherapeutic Doses in Healthy Chinese Subjects, and Assessment of Contezolid Dosing Regimens Based on Pharmacokinetic/Pharmacodynamic Analysis

Clinical therapeutics, 2019-06, Vol.41 (6), p.1164-1174.e4

2019

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CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects

Arteriosclerosis, thrombosis, and vascular biology, 2017-09, Vol.37 (9), p.1770

2017

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Linezolid versus vancomycin for skin and soft tissue infections

Evidence-based child health, 2014-03, Vol.9 (1), p.103-166

2014

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Prolonged use of tedizolid in a pulmonary non-tuberculous mycobacterial infection after linezolid-induced toxicity

Journal of antimicrobial chemotherapy, 2017-02, Vol.72 (2), p.625-628

2017

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Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

Linezolid for Treatment of Chronic Extensively Drug-Resistant Tuberculosis

Once-Weekly Dalbavancin versus Daily Conventional Therapy for Skin Infection

Linezolid in Methicillin-Resistant Staphylococcus aureus Nosocomial Pneumonia: A Randomized, Controlled Study

Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis

Clinical Population Pharmacokinetics and Toxicodynamics of Linezolid

Nonclinical and pharmacokinetic assessments to evaluate the potential of tedizolid and linezolid to affect mitochondrial function

Tedizolid population pharmacokinetics, exposure response, and target attainment

Safety of Anacetrapib in Patients with or at High Risk for Coronary Heart Disease

High plasma linezolid concentration and impaired renal function affect development of linezolid-induced thrombocytopenia

Analysis of thrombocytopenic effects and population pharmacokinetics of linezolid: a dosage strategy according to the trough concentration target and renal function in adult patients

Which trial do we need? Empiric Glycopeptides plus clindamycin versus Oxazolidinones for suspected toxic shock and necrotizing soft tissue infections

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

New Potent Antibacterial Oxazolidinone (MRX-I) with an Improved Class Safety Profile

A phase I study of the safety, tolerability, and pharmacokinetics of contezolid acefosamil after intravenous and oral administration in healthy Chinese subjects

Therapeutic drug monitoring may improve safety outcomes of long-term treatment with linezolid in adult patients

Larger Vancomycin Doses (at Least Four Grams per Day) Are Associated with an Increased Incidence of Nephrotoxicity

Biomarker-Assisted Dose Selection for Safety and Efficacy in Early Development of PNU-100480 for Tuberculosis

Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trials

Safety, tolerability and pharmacokinetics of 21 day multiple oral administration of a new oxazolidinone antibiotic, LCB01-0371, in healthy male subjects

A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections

Tolerability and Pharmacokinetics of Contezolid at Therapeutic and Supratherapeutic Doses in Healthy Chinese Subjects, and Assessment of Contezolid Dosing Regimens Based on Pharmacokinetic/Pharmacodynamic Analysis

CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects

Linezolid versus vancomycin for skin and soft tissue infections

Prolonged use of tedizolid in a pulmonary non-tuberculous mycobacterial infection after linezolid-induced toxicity

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