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Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors

Nature communications, 2019-04, Vol.10 (1), p.1899-15, Article 1899

2019

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Oxaliplatin delivery via chitosan/vitamin E conjugate micelles for improved efficacy and MDR-reversal in breast cancer

Carbohydrate polymers, 2022-04, Vol.282, p.119108, Article 119108

2022

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Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

Journal of controlled release, 2019-02, Vol.295, p.237-249

2019

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Oxaliplatin Pt(IV) prodrugs conjugated to gadolinium-texaphyrin as potential antitumor agents

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (13), p.7021-7029

2020

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Redox-Responsive Polymeric Nanocomplex for Delivery of Cytotoxic Protein and Chemotherapeutics

ACS applied materials & interfaces, 2019-09, Vol.11 (35), p.31638-31648

2019

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Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice

The Journal of clinical investigation, 2020-09, Vol.130 (9), p.4601-4606

2020

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Translational Pharmacokinetic-Toxicodynamic Model of Myelosuppression for Dose Optimization in Combination Chemotherapy of Capecitabine and Oxaliplatin from Rats to Humans

The Journal of pharmacology and experimental therapeutics, 2024-08, Vol.390 (3), p.318-330

2024

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Conjugation of oxaliplatin with PEGylated-nanobody for enhancing tumor targeting and prolonging circulation

Journal of inorganic biochemistry, 2021-10, Vol.223, p.111553-111553, Article 111553

2021

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Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Scientific reports, 2017-09, Vol.7 (1), p.10396-13, Article 10396

2017

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Comparative Study of the Mode of Action of Clinically Approved Platinum-Based Chemotherapeutics

International journal of molecular sciences, 2020-09, Vol.21 (18), p.6928

2020

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Evaluation of Antiproliferative Activity, Safety and Biodistribution of Oxaliplatin and 5-Fluorouracil Loaded Lactoferrin Nanoparticles for the Management of Colon Adenocarcinoma: an In Vitro and an In Vivo Study

Pharmaceutical research, 2018-09, Vol.35 (9), p.178-17, Article 178

2018

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Comparison of Tissue and Blood Concentrations of Oxaliplatin Administrated by Different Modalities of Intraperitoneal Chemotherapy

Annals of surgical oncology, 2019-12, Vol.26 (13), p.4445-4451

2019

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New Trends in Liposome-based Drug Delivery in Colorectal Cancer

Mini reviews in medicinal chemistry, 2019-01, Vol.19 (1), p.3-11

2019

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Co-delivery of 5-fluorouracil and oxaliplatin in novel poly(3-hydroxybutyrate-co-3-hydroxyvalerate acid)/poly(lactic-co-glycolic acid) nanoparticles for colon cancer therapy

International journal of biological macromolecules, 2019-03, Vol.124, p.1299-1311

2019

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Long-Circulating Thermosensitive Liposomes for the Targeted Drug Delivery of Oxaliplatin

International journal of nanomedicine, 2020-01, Vol.15, p.6721-6734

2020

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Bioinspired hyaluronic acid and polyarginine nanoparticles for DACHPt delivery

European journal of pharmaceutics and biopharmaceutics, 2020-05, Vol.150, p.1-13

2020

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Ibudilast for prevention of oxaliplatin-induced acute neurotoxicity: a pilot study assessing preliminary efficacy, tolerability and pharmacokinetic interactions in patients with metastatic gastrointestinal cancer

Cancer chemotherapy and pharmacology, 2020-10, Vol.86 (4), p.547-558

2020

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Hyperthermic intraperitoneal chemotherapy with oxaliplatin for peritoneal carcinomatosis: a clinical pharmacological perspective on a surgical procedure

British journal of clinical pharmacology, 2019-01, Vol.85 (1), p.47-58

2019

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Body surface area‐based vs concentration‐based perioperative intraperitoneal chemotherapy after optimal cytoreductive surgery in colorectal peritoneal surface malignancy treatment: COBOX trial

Journal of surgical oncology, 2019-06, Vol.119 (7), p.999-1010

2019

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Interaction of platinum agents, cisplatin, carboplatin and oxaliplatin against albumin in vivo rats and in vitro study using inductively coupled plasma‐mass spectrometory

Biopharmaceutics & drug disposition, 2019-07, Vol.40 (7), p.242-249

2019

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Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation of oxaliplatin for hematological toxicity in rats

Xenobiotica, 2020-02, Vol.50 (2), p.146-153

2020

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Characterization and Pharmacokinetic Evaluation of Oxaliplatin Long-Circulating Liposomes

BioMed research international, 2021-04, Vol.2021, p.5949804-14

2021

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Effects of route of administration on neural exposure to platinum-based chemotherapy treatment: a pharmacokinetic study in rat

Neurotoxicology (Park Forest South), 2021-09, Vol.86, p.162-165

2021

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Systemic exposure of oxaliplatin and docetaxel in gastric cancer patients with peritonitis carcinomatosis treated with intraperitoneal hyperthermic chemotherapy

European journal of surgical oncology, 2021-02, Vol.47 (2), p.486-489

2021

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Synthesis and structure–activity relationships of tetrazolato-bridged dinuclear platinum(II) complexes: A small modification at tetrazole C5 markedly influences the in vivo antitumor efficacy

Journal of inorganic biochemistry, 2019-03, Vol.192, p.82-86

2019

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Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors

Oxaliplatin delivery via chitosan/vitamin E conjugate micelles for improved efficacy and MDR-reversal in breast cancer

Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

Oxaliplatin Pt(IV) prodrugs conjugated to gadolinium-texaphyrin as potential antitumor agents

Redox-Responsive Polymeric Nanocomplex for Delivery of Cytotoxic Protein and Chemotherapeutics

Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice

Translational Pharmacokinetic-Toxicodynamic Model of Myelosuppression for Dose Optimization in Combination Chemotherapy of Capecitabine and Oxaliplatin from Rats to Humans

Conjugation of oxaliplatin with PEGylated-nanobody for enhancing tumor targeting and prolonging circulation

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Comparative Study of the Mode of Action of Clinically Approved Platinum-Based Chemotherapeutics

Evaluation of Antiproliferative Activity, Safety and Biodistribution of Oxaliplatin and 5-Fluorouracil Loaded Lactoferrin Nanoparticles for the Management of Colon Adenocarcinoma: an In Vitro and an In Vivo Study

Comparison of Tissue and Blood Concentrations of Oxaliplatin Administrated by Different Modalities of Intraperitoneal Chemotherapy

New Trends in Liposome-based Drug Delivery in Colorectal Cancer

Co-delivery of 5-fluorouracil and oxaliplatin in novel poly(3-hydroxybutyrate-co-3-hydroxyvalerate acid)/poly(lactic-co-glycolic acid) nanoparticles for colon cancer therapy

Long-Circulating Thermosensitive Liposomes for the Targeted Drug Delivery of Oxaliplatin

Bioinspired hyaluronic acid and polyarginine nanoparticles for DACHPt delivery

Ibudilast for prevention of oxaliplatin-induced acute neurotoxicity: a pilot study assessing preliminary efficacy, tolerability and pharmacokinetic interactions in patients with metastatic gastrointestinal cancer

Hyperthermic intraperitoneal chemotherapy with oxaliplatin for peritoneal carcinomatosis: a clinical pharmacological perspective on a surgical procedure

Body surface area‐based vs concentration‐based perioperative intraperitoneal chemotherapy after optimal cytoreductive surgery in colorectal peritoneal surface malignancy treatment: COBOX trial

Interaction of platinum agents, cisplatin, carboplatin and oxaliplatin against albumin in vivo rats and in vitro study using inductively coupled plasma‐mass spectrometory

Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation of oxaliplatin for hematological toxicity in rats

Characterization and Pharmacokinetic Evaluation of Oxaliplatin Long-Circulating Liposomes

Effects of route of administration on neural exposure to platinum-based chemotherapy treatment: a pharmacokinetic study in rat

Systemic exposure of oxaliplatin and docetaxel in gastric cancer patients with peritonitis carcinomatosis treated with intraperitoneal hyperthermic chemotherapy

Synthesis and structure–activity relationships of tetrazolato-bridged dinuclear platinum(II) complexes: A small modification at tetrazole C5 markedly influences the in vivo antitumor efficacy

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