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Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein

Journal of medicinal chemistry, 2019-12, Vol.62 (24), p.11280-11300

2019

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Antivirals With Activity Against Mpox: A Clinically Oriented Review

Clinical infectious diseases, 2023-01, Vol.76 (1), p.155-164

2023

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Novel coumarin aminophosphonates as potential multitargeting antibacterial agents against Staphylococcus aureus

European journal of medicinal chemistry, 2023-01, Vol.245 (Pt 1), p.114891-114891, Article 114891

2023

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Building Metabolically Stable and Potent Anti-HIV Thioether-Lipid Analogues of Tenofovir Exalidex: A thorough Pharmacological Analysis

Journal of medicinal chemistry, 2024-10, Vol.67 (20), p.18204-18220

2024

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Diester Prodrugs of a Phosphonate Butyrophilin Ligand Display Improved Cell Potency, Plasma Stability, and Payload Internalization

Journal of medicinal chemistry, 2023-11, Vol.66 (22), p.15309-15325

2023

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Synthetic Methods for Azaheterocyclic Phosphonates and Their Biological Activity: An Update 2004–2024

Chemical reviews, 2024-06, Vol.124 (12), p.7907-7975

2024

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Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production

Journal of medicinal chemistry, 2020-09, Vol.63 (18), p.10433-10459

2020

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MTN-001: randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments

PloS one, 2013-01, Vol.8 (1), p.e55013

2013

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Therapeutic Potential of Sodium Houttuyfonate in Pulmonary Hypertension through Orai-Ca 2+ Channels

American journal of respiratory cell and molecular biology, 2024-09, Vol.71 (3), p.262-263

2024

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Antiviral activity, safety, and pharmacokinetics/pharmacodynamics of tenofovir alafenamide as 10-day monotherapy in HIV-1-positive adults

Journal of acquired immune deficiency syndromes (1999), 2013-08, Vol.63 (4), p.449-455

2013

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Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

mSphere, 2021-02, Vol.6 (1)

2021

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Synthesis and Evaluation of Prodrugs of α‑Carboxy Nucleoside Phosphonates

Journal of organic chemistry, 2022-11, Vol.87 (21), p.14793-14808

2022

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Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets

Cell chemical biology, 2024-09, Vol.31 (9), p.1714-1728.e10

2024

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Biosynthesis of phosphonic and phosphinic acid natural products

Annual review of biochemistry, 2009-01, Vol.78 (1), p.65-94

2009

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Antiviral Drug Resistance of Human Cytomegalovirus

Clinical Microbiology Reviews, 2010-10, Vol.23 (4), p.689-712

2010

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Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6‑Oxopurine Phosphoribosyltransferases

Journal of medicinal chemistry, 2022-03, Vol.65 (5), p.4030-4057

2022

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N -Functionalization of β-aminophosphonates: cytotoxic effects of the new derivatives

Organic & biomolecular chemistry, 2024-05, Vol.22 (19), p.3940-3950

2024

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Design, synthesis and biological evaluation of novel α-aminophosphonate oxadiazoles via optimized iron triflate catalyzed reaction as apoptotic inducers

European journal of medicinal chemistry, 2019-10, Vol.180, p.310-320

2019

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Synthesis, Crystal Structure, and Antibacterial Properties of Silver-Functionalized Low-Dimensional Layered Zirconium Phosphonates

Inorganic chemistry, 2022-01, Vol.61 (4), p.2251-2264

2022

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Prodrugs of phosphonates and phosphates: crossing the membrane barrier

Topics in current chemistry, 2015-01, Vol.360, p.115

2015

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Unachieved antiviral strategies with acyclic nucleoside phosphonates: Dedicated to the memory of dr. Salvatore “Sam” Joseph Enna

Biochemical pharmacology, 2024-10, Vol.228, p.116448, Article 116448

2024

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Synthesis of novel antiproliferative hybrid bis-(3-indolyl)methane phosphonate derivatives

European journal of medicinal chemistry, 2018-10, Vol.158, p.874-883

2018

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Drug Development against Smallpox: Present and Future

Antimicrobial agents and chemotherapy, 2020-03, Vol.64 (4)

2020

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Synthesis, antimicrobial activity, and sustainable release of novel α-aminophosphonate derivatives loaded carrageenan cryogel

International journal of biological macromolecules, 2020-11, Vol.163, p.96-107

2020

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Base-Catalyzed Reaction of Isatins and (3-Hydroxyprop-1-yn-1-yl)phosphonates as a Tool for the Synthesis of Spiro-1,3-dioxolane Oxindoles with Anticancer and Anti-Platelet Properties

Molecules (Basel, Switzerland), 2024-10, Vol.29 (19), p.4764

2024

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Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein

Antivirals With Activity Against Mpox: A Clinically Oriented Review

Novel coumarin aminophosphonates as potential multitargeting antibacterial agents against Staphylococcus aureus

Building Metabolically Stable and Potent Anti-HIV Thioether-Lipid Analogues of Tenofovir Exalidex: A thorough Pharmacological Analysis

Diester Prodrugs of a Phosphonate Butyrophilin Ligand Display Improved Cell Potency, Plasma Stability, and Payload Internalization

Synthetic Methods for Azaheterocyclic Phosphonates and Their Biological Activity: An Update 2004–2024

Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production

MTN-001: randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments

Therapeutic Potential of Sodium Houttuyfonate in Pulmonary Hypertension through Orai-Ca 2+ Channels

Antiviral activity, safety, and pharmacokinetics/pharmacodynamics of tenofovir alafenamide as 10-day monotherapy in HIV-1-positive adults

Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

Synthesis and Evaluation of Prodrugs of α‑Carboxy Nucleoside Phosphonates

Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets

Biosynthesis of phosphonic and phosphinic acid natural products

Antiviral Drug Resistance of Human Cytomegalovirus

Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6‑Oxopurine Phosphoribosyltransferases

N -Functionalization of β-aminophosphonates: cytotoxic effects of the new derivatives

Design, synthesis and biological evaluation of novel α-aminophosphonate oxadiazoles via optimized iron triflate catalyzed reaction as apoptotic inducers

Synthesis, Crystal Structure, and Antibacterial Properties of Silver-Functionalized Low-Dimensional Layered Zirconium Phosphonates

Prodrugs of phosphonates and phosphates: crossing the membrane barrier

Unachieved antiviral strategies with acyclic nucleoside phosphonates: Dedicated to the memory of dr. Salvatore “Sam” Joseph Enna

Synthesis of novel antiproliferative hybrid bis-(3-indolyl)methane phosphonate derivatives

Drug Development against Smallpox: Present and Future

Synthesis, antimicrobial activity, and sustainable release of novel α-aminophosphonate derivatives loaded carrageenan cryogel

Base-Catalyzed Reaction of Isatins and (3-Hydroxyprop-1-yn-1-yl)phosphonates as a Tool for the Synthesis of Spiro-1,3-dioxolane Oxindoles with Anticancer and Anti-Platelet Properties

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