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Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2

Nature (London), 2022-04, Vol.604 (7904), p.134-140

2022

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Recent Advances in the Chemical Synthesis and Evaluation of Anticancer Nucleoside Analogues

Molecules (Basel, Switzerland), 2020-04, Vol.25 (9), p.2050

2020

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The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies

Veterinary microbiology, 2018-06, Vol.219, p.226-233

2018

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Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects

Acta pharmacologica Sinica, 2022-12, Vol.43 (12), p.3130-3138

2022

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The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold

Antiviral research, 2019-02, Vol.162, p.5-21

2019

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An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral

Antiviral research, 2021-11, Vol.195, p.105180-105180, Article 105180

2021

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Efficient Synthesis of Purine Nucleoside Analogs by a New Trimeric Purine Nucleoside Phosphorylase from Aneurinibacillus migulanus AM007

Molecules (Basel, Switzerland), 2019-12, Vol.25 (1), p.100

2019

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Tri-Cyclic Nucleobase Analogs and their Ribosides as Substrates of Purine-Nucleoside Phosphorylases. II Guanine and Isoguanine Derivatives

Molecules (Basel, Switzerland), 2019-04, Vol.24 (8), p.1493

2019

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Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues

Angewandte Chemie (International ed.), 2016-04, Vol.55 (17), p.5255-5258

International ed. in English, 2016

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Nucleosides for the treatment of respiratory RNA virus infections

Antiviral chemistry & chemotherapy, 2018-01, Vol.26, p.2040206618764483-2040206618764483

2018

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Validation of hepatocellular carcinoma risk scores in Japanese chronic hepatitis B cohort receiving nucleot(s)ide analog

Journal of gastroenterology and hepatology, 2020-09, Vol.35 (9), p.1595-1601

2020

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Chemoselective and Diastereoselective Synthesis of C‐Aryl Nucleoside Analogues by Nickel‐Catalyzed Cross‐Coupling of Furanosyl Acetates with Aryl Iodides

Angewandte Chemie International Edition, 2022-01, Vol.61 (1), p.e202110391-n/a

International ed. in English, 2022

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The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro

Archives of toxicology, 2022-08, Vol.96 (8), p.2341-2360

2022

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Phenotypic Test of Benzo[4,5]imidazo[1,2-c]pyrimidinone-Based Nucleoside and Non-Nucleoside Derivatives against DNA and RNA Viruses, Including Coronaviruses

International journal of molecular sciences, 2023-10, Vol.24 (19), p.14540

2023

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Identifying Small-Molecule Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase by Establishing a Fluorometric Assay

Frontiers in immunology, 2022-04, Vol.13, p.844749-844749

2022

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Nucleoside Analogs with Selective Antiviral Activity against Dengue Fever and Japanese Encephalitis Viruses

Antimicrobial agents and chemotherapy, 2019-07, Vol.63 (7)

2019

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New Derivatives of 5-Substituted Uracils: Potential Agents with a Wide Spectrum of Biological Activity

Molecules (Basel, Switzerland), 2022-04, Vol.27 (9), p.2866

2022

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DNA Trojan Horses: Self‐Assembled Floxuridine‐Containing DNA Polyhedra for Cancer Therapy

Angewandte Chemie International Edition, 2017-10, Vol.56 (41), p.12528-12532

International ed. in English, 2017

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Non-canonical nucleosides: Biomimetic triphosphorylation, incorporation into mRNA and effects on translation and structure

The FEBS journal, 2023-10, Vol.290 (20), p.4899-4920

2023

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Synthesis and Cytotoxic Activity of New Thiazolopyrimidine Sugar Hydrazones and Their Derived Acyclic Nucleoside Analogues

Molecules (Basel, Switzerland), 2020-01, Vol.25 (2), p.399

2020

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Broad-Spectrum Antiviral Strategies and Nucleoside Analogues

Viruses, 2021-04, Vol.13 (4), p.667

2021

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Quantification and epigenetic evaluation of the residual pool of hepatitis B covalently closed circular DNA in long-term nucleoside analogue-treated patients

Scientific reports, 2020-12, Vol.10 (1), p.21097, Article 21097

2020

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Preparation of 4′‐Spirocyclobutyl Nucleoside Analogues as Novel and Versatile Adenosine Scaffolds

Chemistry : a European journal, 2019-12, Vol.25 (67), p.15419-15423

2019

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Current and future use of nucleo(s)tide prodrugs in the treatment of hepatitis C virus infection

Antiviral chemistry & chemotherapy, 2018-01, Vol.26, p.2040206618756430

Dousson, Cyril B

2018

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Treatment outcomes with purine nucleoside analog alone or with rituximab for hairy cell leukemia at first relapse

European journal of haematology, 2022-05, Vol.108 (5), p.379-382

2022

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Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2

Recent Advances in the Chemical Synthesis and Evaluation of Anticancer Nucleoside Analogues

The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies

Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects

The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold

An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral

Efficient Synthesis of Purine Nucleoside Analogs by a New Trimeric Purine Nucleoside Phosphorylase from Aneurinibacillus migulanus AM007

Tri-Cyclic Nucleobase Analogs and their Ribosides as Substrates of Purine-Nucleoside Phosphorylases. II Guanine and Isoguanine Derivatives

Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues

Nucleosides for the treatment of respiratory RNA virus infections

Validation of hepatocellular carcinoma risk scores in Japanese chronic hepatitis B cohort receiving nucleot(s)ide analog

Chemoselective and Diastereoselective Synthesis of C‐Aryl Nucleoside Analogues by Nickel‐Catalyzed Cross‐Coupling of Furanosyl Acetates with Aryl Iodides

The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro

Phenotypic Test of Benzo[4,5]imidazo[1,2-c]pyrimidinone-Based Nucleoside and Non-Nucleoside Derivatives against DNA and RNA Viruses, Including Coronaviruses

Identifying Small-Molecule Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase by Establishing a Fluorometric Assay

Nucleoside Analogs with Selective Antiviral Activity against Dengue Fever and Japanese Encephalitis Viruses

New Derivatives of 5-Substituted Uracils: Potential Agents with a Wide Spectrum of Biological Activity

DNA Trojan Horses: Self‐Assembled Floxuridine‐Containing DNA Polyhedra for Cancer Therapy

Non-canonical nucleosides: Biomimetic triphosphorylation, incorporation into mRNA and effects on translation and structure

Synthesis and Cytotoxic Activity of New Thiazolopyrimidine Sugar Hydrazones and Their Derived Acyclic Nucleoside Analogues

Broad-Spectrum Antiviral Strategies and Nucleoside Analogues

Quantification and epigenetic evaluation of the residual pool of hepatitis B covalently closed circular DNA in long-term nucleoside analogue-treated patients

Preparation of 4′‐Spirocyclobutyl Nucleoside Analogues as Novel and Versatile Adenosine Scaffolds

Current and future use of nucleo(s)tide prodrugs in the treatment of hepatitis C virus infection

Treatment outcomes with purine nucleoside analog alone or with rituximab for hairy cell leukemia at first relapse

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