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Nicotinamide N‐methyltransferase gene silencing enhances chemosensitivity of melanoma cell lines

Pigment cell and melanoma research, 2021-11, Vol.34 (6), p.1039-1048

2021

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Nicotinamide N-methyltransferase enhances chemoresistance in breast cancer through SIRT1 protein stabilization

Breast cancer research : BCR, 2019-05, Vol.21 (1), p.64-64, Article 64

2019

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Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

Nature (London), 2014-04, Vol.508 (7495), p.258-262

2014

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Complex roles of nicotinamide N-methyltransferase in cancer progression

Cell death & disease, 2022-03, Vol.13 (3), p.267-267, Article 267

2022

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High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide N‑Methyltransferase (NNMT)

Journal of medicinal chemistry, 2019-11, Vol.62 (21), p.9837-9873

2019

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Genetic Nicotinamide N -Methyltransferase ( Nnmt ) Deficiency in Male Mice Improves Insulin Sensitivity in Diet-Induced Obesity but Does Not Affect Glucose Tolerance

Diabetes (New York, N.Y.), 2019-03, Vol.68 (3), p.527-542

2019

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Gastric Cancer With the Increased Nicotinamide N-methyltransferase-positive Stromal Cells Includes Unfavorable Prognosis-related Cancer-associated Fibroblasts

Anticancer research, 2024-04, Vol.44 (4), p.1653-1660

2024

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Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway

Molecular and cellular biochemistry, 2019-10, Vol.460 (1-2), p.93-103

2019

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The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease

Scientific reports, 2022-04, Vol.12 (1), p.6398-6398, Article 6398

2022

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A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N‑Methyltransferase

Biochemistry (Easton), 2016-09, Vol.55 (37), p.5307-5315

2016

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Structure–Activity Relationship for Small Molecule Inhibitors of Nicotinamide N‑Methyltransferase

Journal of medicinal chemistry, 2017-06, Vol.60 (12), p.5015-5028

2017

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Targeting nicotinamide N‐methyltransferase decreased aggressiveness of osteosarcoma cells

European journal of clinical investigation, 2024-06, Vol.54 (6), p.e14185-n/a

2024

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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

Biochemical pharmacology, 2018-01, Vol.147, p.141-152

2018

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Nicotinamide N-Methyltransferase (NNMT) is Involved in Gastric Adenocarcinoma Immune Infiltration by Driving Amino Acid Metabolism

Nutrition and cancer, 2024-09, Vol.76 (8), p.745-759

2024

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Stromal nicotinamide N-methyltransferase orchestrates the crosstalk between fibroblasts and tumour cells in oral squamous cell carcinoma: evidence from patient-derived assembled organoids

Oncogene, 2023-04, Vol.42 (15), p.1166-1180

2023

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Nicotinamide N‐methyltransferase ameliorates renal fibrosis by its metabolite 1‐methylnicotinamide inhibiting the TGF‐β1/Smad3 pathway

The FASEB journal, 2022-03, Vol.36 (3), p.e22084-n/a

2022

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Nicotinamide N-methyltransferase upregulation contributes to palmitate-elicited peroxisome proliferator-activated receptor transactivation in hepatocytes

American Journal of Physiology: Cell Physiology, 2023-07, Vol.325 (1), p.C29-C41

2023

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Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

Diabetologia, 2015-04, Vol.58 (4), p.799-808

2015

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Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase

Bioorganic & medicinal chemistry letters, 2018-03, Vol.28 (5), p.922-925

2018

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Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice

Scientific reports, 2022-01, Vol.12 (1), p.484-484, Article 484

2022

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Glucose availability regulates nicotinamide N-methyltransferase expression in adipocytes

Life sciences (1973), 2020-05, Vol.248, p.117474-7, Article 117474

2020

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Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice

Scientific reports, 2021-03, Vol.11 (1), p.5637-16, Article 5637

2021

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Novel Inhibitors of Nicotinamide- N -Methyltransferase for the Treatment of Metabolic Disorders

Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.991

2021

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Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N‑Methyltransferase Activity

Biochemistry (Easton), 2017-02, Vol.56 (6), p.824-832

2017

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Enhancing nicotinamide N-methyltransferase bisubstrate inhibitor activity through 7-deazaadenosine and linker modifications

Bioorganic chemistry, 2024-02, Vol.143, p.106963-106963, Article 106963

2024

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Nicotinamide N‐methyltransferase gene silencing enhances chemosensitivity of melanoma cell lines

Nicotinamide N-methyltransferase enhances chemoresistance in breast cancer through SIRT1 protein stabilization

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

Complex roles of nicotinamide N-methyltransferase in cancer progression

High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide N‑Methyltransferase (NNMT)

Genetic Nicotinamide N -Methyltransferase ( Nnmt ) Deficiency in Male Mice Improves Insulin Sensitivity in Diet-Induced Obesity but Does Not Affect Glucose Tolerance

Gastric Cancer With the Increased Nicotinamide N-methyltransferase-positive Stromal Cells Includes Unfavorable Prognosis-related Cancer-associated Fibroblasts

Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway

The significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease

A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N‑Methyltransferase

Structure–Activity Relationship for Small Molecule Inhibitors of Nicotinamide N‑Methyltransferase

Targeting nicotinamide N‐methyltransferase decreased aggressiveness of osteosarcoma cells

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

Nicotinamide N-Methyltransferase (NNMT) is Involved in Gastric Adenocarcinoma Immune Infiltration by Driving Amino Acid Metabolism

Stromal nicotinamide N-methyltransferase orchestrates the crosstalk between fibroblasts and tumour cells in oral squamous cell carcinoma: evidence from patient-derived assembled organoids

Nicotinamide N‐methyltransferase ameliorates renal fibrosis by its metabolite 1‐methylnicotinamide inhibiting the TGF‐β1/Smad3 pathway

Nicotinamide N-methyltransferase upregulation contributes to palmitate-elicited peroxisome proliferator-activated receptor transactivation in hepatocytes

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase

Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice

Glucose availability regulates nicotinamide N-methyltransferase expression in adipocytes

Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice

Novel Inhibitors of Nicotinamide- N -Methyltransferase for the Treatment of Metabolic Disorders

Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N‑Methyltransferase Activity

Enhancing nicotinamide N-methyltransferase bisubstrate inhibitor activity through 7-deazaadenosine and linker modifications

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