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NUP98 Rearrangements in AML: Molecular Mechanisms and Clinical Implications

Onco, 2023-07, Vol.3 (3), p.147-164

Mohanty, Sagarajit

2023

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Acute onset of constrictive pericarditis due to acute myelomonocytic leukemia: A case and literature review

Internal Medicine, 2024, pp.3505-24

2024

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Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease

Neuron (Cambridge, Mass.), 2018-09, Vol.99 (5), p.925-940.e7

2018

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SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (45), p.28344-28354

2020

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Nup98 recruits the Wdr82-Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells

Genes & development, 2017-11, Vol.31 (22), p.2222-2234

2017

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Distinct pathologic feature of myeloid neoplasm with t(v;11p15); NUP98 rearrangement

Human pathology, 2022-05, Vol.123, p.11-19

2022

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AML-158 Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22, p.S220

2022

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AML-283 The Genetic Landscape of NUP98-Rearranged Pediatric Leukemia

Clinical lymphoma, myeloma and leukemia, 2022-10, Vol.22, p.S233

2022

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Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure

Cell reports (Cambridge), 2023-08, Vol.42 (8), p.112884-112884, Article 112884

2023

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NUP98 - a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer

BMC cancer, 2019-04, Vol.19 (1), p.236-236, Article 236

2019

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Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex

Biochemical and biophysical research communications, 2021-01, Vol.536, p.59-66

2021

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Adult acute myeloid leukemia patients with NUP98 rearrangement have frequent cryptic translocations and unfavorable outcome

Leukemia & lymphoma, 2022-07, Vol.63 (8), p.1907-1916

2022

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NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis

Cancer cell, 2016-12, Vol.30 (6), p.863-878

2016

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SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98

mBio, 2021-04, Vol.12 (2)

2021

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Rare NUP98::PRRX1 fusion transcript in a therapy-related acute myeloid leukemia associated with del(7q) following chemotherapy for diffuse large B-cell lymphoma

Cancer genetics, 2024-06, Vol.284-285, p.12-15

2024

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Nucleoporin Nup98 is an essential factor for ipo4 dependent protein import

Journal of cellular biochemistry, 2024-07, Vol.125 (7), p.e30573-n/a

2024

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Mitotic Disassembly of Nuclear Pore Complexes Involves CDK1- and PLK1-Mediated Phosphorylation of Key Interconnecting Nucleoporins

Developmental cell, 2017-10, Vol.43 (2), p.141-156.e7

2017

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Acute myeloid leukemia with NUP98::RARG resembling acute promyelocytic leukemia accompanying ARID1B gene mutation

Hematology (Luxembourg), 2023-12, Vol.28 (1), p.2227495-2227495

2023

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Circ-NUP98 Promotes Lung Adenocarcinoma Development Through Regulating CBX1 by miR-188-3p

Biochemical genetics, 2023-12

2023

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Clinical implications of NUP98::NSD1 fusion at diagnosis in adult FLT3-ITD positive AML

European journal of haematology, 2023-10, Vol.111 (4), p.620-627

2023

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Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

Virology (New York, N.Y.), 2013-05, Vol.440 (1), p.8-18

2013

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Influence of siRNA complexes on the reproduction of influenza A virus (Orthomyxoviridae: Alphainfluenzavirus) in vivo

Voprosy virusologiĭ, 2023-05, Vol.68 (2), p.95-104

2023

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Pediatric acute erythroid leukemias with monocytic antigen expression and novel chromosomal translocations

Pediatric blood & cancer, 2023-08, Vol.70 (8), p.e30333-n/a

2023

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Clinical features and prognosis of patients with myeloid neoplasms harboring t(7;11)(p15;p15) translocation: a single-center retrospective study

BMC cancer, 2024-08, Vol.24 (1), p.1-11, Article 955

2024

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The nuclear pore protein NUP98 impedes LTR-driven basal gene expression of HIV-1, viral propagation, and infectivity

Frontiers in immunology, 2024-02, Vol.15, p.1330738-1330738

2024

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NUP98 Rearrangements in AML: Molecular Mechanisms and Clinical Implications

Acute onset of constrictive pericarditis due to acute myelomonocytic leukemia: A case and literature review

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease

SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling

Nup98 recruits the Wdr82-Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells

Distinct pathologic feature of myeloid neoplasm with t(v;11p15); NUP98 rearrangement

AML-158 Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation

AML-283 The Genetic Landscape of NUP98-Rearranged Pediatric Leukemia

Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure

NUP98 - a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer

Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex

Adult acute myeloid leukemia patients with NUP98 rearrangement have frequent cryptic translocations and unfavorable outcome

NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis

SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98

Rare NUP98::PRRX1 fusion transcript in a therapy-related acute myeloid leukemia associated with del(7q) following chemotherapy for diffuse large B-cell lymphoma

Nucleoporin Nup98 is an essential factor for ipo4 dependent protein import

Mitotic Disassembly of Nuclear Pore Complexes Involves CDK1- and PLK1-Mediated Phosphorylation of Key Interconnecting Nucleoporins

Acute myeloid leukemia with NUP98::RARG resembling acute promyelocytic leukemia accompanying ARID1B gene mutation

Circ-NUP98 Promotes Lung Adenocarcinoma Development Through Regulating CBX1 by miR-188-3p

Clinical implications of NUP98::NSD1 fusion at diagnosis in adult FLT3-ITD positive AML

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

Influence of siRNA complexes on the reproduction of influenza A virus (Orthomyxoviridae: Alphainfluenzavirus) in vivo

Pediatric acute erythroid leukemias with monocytic antigen expression and novel chromosomal translocations

Clinical features and prognosis of patients with myeloid neoplasms harboring t(7;11)(p15;p15) translocation: a single-center retrospective study

The nuclear pore protein NUP98 impedes LTR-driven basal gene expression of HIV-1, viral propagation, and infectivity

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