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N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1

The Journal of experimental medicine, 2018-10, Vol.215 (10), p.2600-2616

2018

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Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells

The Journal of biological chemistry, 2019-11, Vol.294 (48), p.18131-18149

2019

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Nuclear Factor Erythroid-2 Like 1 (NFE2L1): Structure, function and regulation

Gene, 2016-06, Vol.584 (1), p.17-25

2016

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Mitochondrial biogenesis and clearance: a balancing act

The FEBS journal, 2017-01, Vol.284 (2), p.183-195

2017

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Ferroptosis regulation by the NGLY1/NFE2L1 pathway

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (11), p.e2118646119-e2118646119

2022

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Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

Nature communications, 2021-09, Vol.12 (1), p.5270-15, Article 5270

2021

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Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

The Journal of cell biology, 2024-06, Vol.223 (6)

2024

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Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop

Molecular cell, 2010-10, Vol.40 (1), p.147-158

2010

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Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

Toxicology and applied pharmacology, 2010-04, Vol.244 (1), p.16-20

2010

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Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate

Biochimica et biophysica acta. Molecular cell research, 2024-02, Vol.1871 (2), p.119644-119644, Article 119644

2024

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NF-E2-Related Factor 1 (Nrf1) Serves as a Novel Regulator of Hepatic Lipid Metabolism through Regulation of the Lipin1 and PGC-1β Genes

Molecular and Cellular Biology, 2012-07, Vol.32 (14), p.2760-2770

2012

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Pro-renin receptor suppresses mitochondrial biogenesis and function via AMPK/SIRT-1/ PGC-1α pathway in diabetic kidney

PloS one, 2019-12, Vol.14 (12), p.e0225728-e0225728

2019

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Long-isoform NRF1 protects against arsenic cytotoxicity in mouse bone marrow-derived mesenchymal stem cells by suppressing mitochondrial ROS and facilitating arsenic efflux

Toxicology and applied pharmacology, 2020-11, Vol.407, p.115251, Article 115251

2020

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Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

Nature medicine, 2018-03, Vol.24 (3), p.292-303

2018

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EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer

The EMBO journal, 2015-12, Vol.34 (23), p.2953-2970

2015

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Estrogenic control of mitochondrial function and biogenesis

Journal of cellular biochemistry, 2008-12, Vol.105 (6), p.1342-1351

Klinge, Carolyn M.

2008

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Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism

Autophagy, 2019-01, Vol.15 (1), p.58-77

2019

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A novel nonsense variant in the NFE2L1 transcription factor in a patient with developmental delay, hypotonia, genital anomalies, and failure to thrive

Human mutation, 2022-04, Vol.43 (4), p.471-476

2022

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T-2 toxin upregulates the expression of human cytochrome P450 1A1 (CYP1A1) by enhancing NRF1 and Sp1 interaction

Toxicology letters, 2019-10, Vol.315, p.77-86

2019

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NRF1 and NRF2 mRNA and Protein Expression Decrease Early during Melanoma Carcinogenesis: An Insight into Survival and MicroRNAs

Oxidative medicine and cellular longevity, 2019, Vol.2019, p.2647068-15

2019

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A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy

Human molecular genetics, 2016-05, Vol.25 (10), p.1979-1989

2016

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Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice

Food and chemical toxicology, 2021-12, Vol.158, p.112633-112633, Article 112633

2021

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Endoplasmic reticulum stress induces cardiac dysfunction through architectural modifications and alteration of mitochondrial function in cardiomyocytes

Cardiovascular research, 2019-02, Vol.115 (2), p.328-342

2019

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Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice

Food and chemical toxicology, 2020-12, Vol.146, p.111836, Article 111836

2020

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Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex

The Journal of biological chemistry, 2019-02, Vol.294 (6), p.2036-2045

2019

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N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1

Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells

Nuclear Factor Erythroid-2 Like 1 (NFE2L1): Structure, function and regulation

Mitochondrial biogenesis and clearance: a balancing act

Ferroptosis regulation by the NGLY1/NFE2L1 pathway

Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop

Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate

NF-E2-Related Factor 1 (Nrf1) Serves as a Novel Regulator of Hepatic Lipid Metabolism through Regulation of the Lipin1 and PGC-1β Genes

Pro-renin receptor suppresses mitochondrial biogenesis and function via AMPK/SIRT-1/ PGC-1α pathway in diabetic kidney

Long-isoform NRF1 protects against arsenic cytotoxicity in mouse bone marrow-derived mesenchymal stem cells by suppressing mitochondrial ROS and facilitating arsenic efflux

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer

Estrogenic control of mitochondrial function and biogenesis

Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism

A novel nonsense variant in the NFE2L1 transcription factor in a patient with developmental delay, hypotonia, genital anomalies, and failure to thrive

T-2 toxin upregulates the expression of human cytochrome P450 1A1 (CYP1A1) by enhancing NRF1 and Sp1 interaction

NRF1 and NRF2 mRNA and Protein Expression Decrease Early during Melanoma Carcinogenesis: An Insight into Survival and MicroRNAs

A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy

Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice

Endoplasmic reticulum stress induces cardiac dysfunction through architectural modifications and alteration of mitochondrial function in cardiomyocytes

Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice

Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex

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