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Structure and mechanism of the RNA polymerase II transcription machinery

Genes & development, 2020-04, Vol.34 (7-8), p.465-488

2020

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Regulation of Promoter Proximal Pausing of RNA Polymerase II in Metazoans

Journal of molecular biology, 2021-07, Vol.433 (14), p.166897-166897, Article 166897

2021

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NELF complex fosters BRCA1 and RAD51 recruitment to DNA damage sites and modulates sensitivity to PARP inhibition

DNA repair, 2021-01, Vol.97, p.103025-103025, Article 103025

2021

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NELF‐E is recruited to DNA double‐strand break sites to promote transcriptional repression and repair

EMBO reports, 2017-05, Vol.18 (5), p.745-764

2017

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Competitive sorption in CO2/CH4 separations: the case of HAB-6FDA polyimide and its TR derivative and a general analysis of its impact on the selectivity of glassy polymers at multicomponent conditions

Journal of membrane science, 2020-10, Vol.612, p.118374, Article 118374

2020

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NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release

Molecular cell, 2020-04, Vol.78 (2), p.261-274.e5

2020

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Gas sorption and diffusion in perfluoro(butenyl vinyl ether) based perfluoropolymeric membranes

Journal of membrane science, 2022-02, Vol.644, p.120095, Article 120095

2022

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Structural basis of the human negative elongation factor NELF-B/C/E ternary complex

Biochemical and biophysical research communications, 2023-10, Vol.677, p.155-161

2023

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Assessment of the roles of Spt5-nucleic acid contacts in promoter proximal pausing of RNA polymerase II

The Journal of biological chemistry, 2023-09, Vol.299 (9), p.105106-105106, Article 105106

2023

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SPT6 functions in transcriptional pause/release via PAF1C recruitment

Molecular cell, 2022-09, Vol.82 (18), p.3412-3423.e5

2022

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Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing

Molecular cell, 2024-04, Vol.84 (7), p.1243-1256.e5

2024

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Enabling experimental characterization and prediction of ternary mixed-gas sorption in polymers: C2H6/CO2/CH4 in PIM-1

Chemical engineering journal (Lausanne, Switzerland : 1996), 2021-12, Vol.426, p.130715, Article 130715

2021

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Towards a systematic determination of multicomponent gas separation with membranes: the case of CO2/CH4 in cellulose acetates

Journal of membrane science, 2021-06, Vol.628, p.119226, Article 119226

2021

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RNA Polymerase II Elongation Control

Annual review of biochemistry, 2012-01, Vol.81 (1), p.119-143

2012

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Estimating Gas Sorption In Polymeric Membranes From The Molecular Structure: A Machine Learning Based Group Contribution Method For The Non-Equilibrium Lattice Fluid Model (ML-GC-NELF)

Journal of membrane science, 2024-02, Vol.691, p.122220, Article 122220

2024

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RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription

Genes & development, 2022-07, Vol.36 (13-14), p.770-789

2022

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Transcriptional lockdown during acute proteotoxic stress

Trends in biochemical sciences (Amsterdam. Regular ed.), 2022-08, Vol.47 (8), p.660-672

Sawarkar, Ritwick

2022

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Transcriptional elongation control in developmental gene expression, aging, and disease

Molecular cell, 2023-11, Vol.83 (22), p.3972-3999

2023

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A transcriptionally repressed quiescence program is associated with paused RNA polymerase II and is poised for cell cycle re-entry

Journal of cell science, 2022-08, Vol.135 (15)

2022

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Sorption of CO2/CH4 mixtures in TZ-PIM, PIM-1 and PTMSP: Experimental data and NELF-model analysis of competitive sorption and selectivity in mixed gases

Journal of membrane science, 2019-09, Vol.585, p.136-149

2019

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Stress-induced nuclear condensation of NELF drives transcriptional downregulation

Molecular cell, 2021-03, Vol.81 (5), p.1013-1026.e11

2021

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TFIID Enables RNA Polymerase II Promoter-Proximal Pausing

Molecular cell, 2020-05, Vol.78 (4), p.785-793.e8

2020

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Development of an extended model for the permeation of environmentally hazardous CO2 gas across asymmetric hollow fiber composite membranes

Journal of hazardous materials, 2021-09, Vol.417, p.126000-126000, Article 126000

2021

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Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation

Developmental cell, 2021-04, Vol.56 (7), p.1014-1029.e7

2021

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NELF‐A controls Drosophila healthspan by regulating heat‐shock protein‐mediated cellular protection and heterochromatin maintenance

Aging cell, 2021-05, Vol.20 (5), p.e13348-n/a

2021

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Structure and mechanism of the RNA polymerase II transcription machinery

Regulation of Promoter Proximal Pausing of RNA Polymerase II in Metazoans

NELF complex fosters BRCA1 and RAD51 recruitment to DNA damage sites and modulates sensitivity to PARP inhibition

NELF‐E is recruited to DNA double‐strand break sites to promote transcriptional repression and repair

Competitive sorption in CO2/CH4 separations: the case of HAB-6FDA polyimide and its TR derivative and a general analysis of its impact on the selectivity of glassy polymers at multicomponent conditions

NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release

Gas sorption and diffusion in perfluoro(butenyl vinyl ether) based perfluoropolymeric membranes

Structural basis of the human negative elongation factor NELF-B/C/E ternary complex

Assessment of the roles of Spt5-nucleic acid contacts in promoter proximal pausing of RNA polymerase II

SPT6 functions in transcriptional pause/release via PAF1C recruitment

Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing

Enabling experimental characterization and prediction of ternary mixed-gas sorption in polymers: C2H6/CO2/CH4 in PIM-1

Towards a systematic determination of multicomponent gas separation with membranes: the case of CO2/CH4 in cellulose acetates

RNA Polymerase II Elongation Control

Estimating Gas Sorption In Polymeric Membranes From The Molecular Structure: A Machine Learning Based Group Contribution Method For The Non-Equilibrium Lattice Fluid Model (ML-GC-NELF)

RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription

Transcriptional lockdown during acute proteotoxic stress

Transcriptional elongation control in developmental gene expression, aging, and disease

A transcriptionally repressed quiescence program is associated with paused RNA polymerase II and is poised for cell cycle re-entry

Sorption of CO2/CH4 mixtures in TZ-PIM, PIM-1 and PTMSP: Experimental data and NELF-model analysis of competitive sorption and selectivity in mixed gases

Stress-induced nuclear condensation of NELF drives transcriptional downregulation

TFIID Enables RNA Polymerase II Promoter-Proximal Pausing

Development of an extended model for the permeation of environmentally hazardous CO2 gas across asymmetric hollow fiber composite membranes

Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation

NELF‐A controls Drosophila healthspan by regulating heat‐shock protein‐mediated cellular protection and heterochromatin maintenance

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