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Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transporters

Proceedings of the National Academy of Sciences - PNAS, 2021-05, Vol.118 (21), p.1-9

2021

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Zebrafish ( Danio rerio ) larva as an in vivo vertebrate model to study renal function

American journal of physiology. Renal physiology, 2022-03, Vol.322 (3), p.F280-F294

2022

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m6A Regulator-Mediated Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Acute Myeloid Leukemia

Frontiers in immunology, 2021-11, Vol.12, p.789914-789914

2021

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Biliary excretion of arsenic by human HepaRG cells is stimulated by selenide and mediated by the multidrug resistance protein 2 (MRP2/ABCC2)

Biochemical pharmacology, 2021-11, Vol.193, p.114799-114799, Article 114799

2021

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Tanshinone IIA prevents acetaminophen‐induced nephrotoxicity through the activation of the Nrf2‐Mrp2/4 pathway in mice

Environmental toxicology, 2022-07, Vol.37 (7), p.1618-1628

2022

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Targeting METTL3 enhances the chemosensitivity of non-small cell lung cancer cells by decreasing ABCC2 expression in an m 6 A-YTHDF1-dependent manner

International journal of biological sciences, 2024, Vol.20 (12), p.4750-4766

2024

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Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model

GeroScience, 2024-04, Vol.46 (6), p.5967-5980

2024

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Properties of AdeABC and AdeIJK efflux systems of Acinetobacter baumannii compared with those of the AcrAB-TolC system of Escherichia coli

Antimicrobial agents and chemotherapy, 2014-12, Vol.58 (12), p.7250-7257

2014

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Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched

Cell, 2018-11, Vol.175 (5), p.1352-1364.e14

2018

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Renal Drug Transporters and Drug Interactions

Clinical pharmacokinetics, 2017-08, Vol.56 (8), p.825-892

2017

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Structure of the AcrAB–TolC multidrug efflux pump

Nature (London), 2014-05, Vol.509 (7501), p.512-515

2014

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A designer enzyme for hydrazone and oxime formation featuring an unnatural catalytic aniline residue

Nature chemistry, 2018-09, Vol.10 (9), p.946-952

2018

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Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (13), p.3509-3514

2016

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Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps

Nature communications, 2022-01, Vol.13 (1), p.115-115, Article 115

2022

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Targeting multidrug resistance protein 1 (MRP1, ABCC1): past, present, and future

Annual review of pharmacology and toxicology, 2014-01, Vol.54 (1), p.95-117

Cole, Susan P C

2014

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ATP-binding cassette efflux transporters and MDR in cancer

Drug discovery today, 2023-05, Vol.28 (5), p.103537-103537, Article 103537

2023

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ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP

Immunity (Cambridge, Mass.), 2022-10, Vol.55 (10), p.1799-1812.e4

2022

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Structural basis for the inhibition of bacterial multidrug exporters

Nature (London), 2013-08, Vol.500 (7460), p.102-106

2013

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Cryo-EM analysis of a membrane protein embedded in the liposome

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (31), p.18497-18503

2020

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Functional redundancy of two ABC transporter proteins in mediating toxicity of Bacillus thuringiensis to cotton bollworm

PLoS pathogens, 2020-03, Vol.16 (3), p.e1008427

2020

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A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity

Cell reports (Cambridge), 2019-02, Vol.26 (6), p.1544-1556.e8

2019

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Structure and activity of lipid bilayer within a membrane-protein transporter

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (51), p.12985-12990

2018

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A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development

Toxicological sciences, 2013-11, Vol.136 (1), p.216-241

2013

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Still rocking in the structural era: A molecular overview of the small multidrug resistance (SMR) transporter family

The Journal of biological chemistry, 2022-10, Vol.298 (10), p.102482, Article 102482

2022

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Multidrug Efflux Pumps of Gram-Positive Bacteria

Drug resistance updates, 2016-07, Vol.27, p.1-13

2016

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Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transporters

Zebrafish ( Danio rerio ) larva as an in vivo vertebrate model to study renal function

m6A Regulator-Mediated Methylation Modification Patterns and Tumor Microenvironment Infiltration Characterization in Acute Myeloid Leukemia

Biliary excretion of arsenic by human HepaRG cells is stimulated by selenide and mediated by the multidrug resistance protein 2 (MRP2/ABCC2)

Tanshinone IIA prevents acetaminophen‐induced nephrotoxicity through the activation of the Nrf2‐Mrp2/4 pathway in mice

Targeting METTL3 enhances the chemosensitivity of non-small cell lung cancer cells by decreasing ABCC2 expression in an m 6 A-YTHDF1-dependent manner

Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model

Properties of AdeABC and AdeIJK efflux systems of Acinetobacter baumannii compared with those of the AcrAB-TolC system of Escherichia coli

Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched

Renal Drug Transporters and Drug Interactions

Structure of the AcrAB–TolC multidrug efflux pump

A designer enzyme for hydrazone and oxime formation featuring an unnatural catalytic aniline residue

Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives

Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps

Targeting multidrug resistance protein 1 (MRP1, ABCC1): past, present, and future

ATP-binding cassette efflux transporters and MDR in cancer

ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP

Structural basis for the inhibition of bacterial multidrug exporters

Cryo-EM analysis of a membrane protein embedded in the liposome

Functional redundancy of two ABC transporter proteins in mediating toxicity of Bacillus thuringiensis to cotton bollworm

A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity

Structure and activity of lipid bilayer within a membrane-protein transporter

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development

Still rocking in the structural era: A molecular overview of the small multidrug resistance (SMR) transporter family

Multidrug Efflux Pumps of Gram-Positive Bacteria

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