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Comparative Error-Free and Error-Prone Translesion Synthesis of N(2)-2'-Deoxyguanosine Adducts Formed by Mitomycin C and Its Metabolite, 2,7-Diaminomitosene, in Human Cells

Chemical research in toxicology, 2016-05, Vol.29 (5), p.933

2016

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Cytotoxicity, crosslinking and biological activity of three mitomycins

Bioorganic chemistry, 2022-06, Vol.123, p.105744-105744, Article 105744

2022

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Interdependent Sequence Selectivity and Diastereoselectivity in the Alkylation of DNA by Decarbamoylmitomycin C

Chemistry : a European journal, 2018-09, Vol.24 (50), p.13278-13289

2018

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Synthesis-Enabled Probing of Mitosene Structural Space Leads to Improved IC50 over Mitomycin C

Angewandte Chemie (International ed.), 2014-08, Vol.53 (35), p.9302-9305

2014

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Synthesis of Mitomycin C and Decarbamoylmitomycin C N(2) deoxyguanosine-adducts

Bioorganic chemistry, 2016-04, Vol.65, p.90-99

2016

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Synthesis of a major mitomycin C DNA adduct via a triaminomitosene

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (23), p.7198-7200

2012

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Mapping DNA Adducts of Mitomycin C and Decarbamoyl Mitomycin C in Cell Lines Using Liquid Chromatography/Electrospray Tandem Mass Spectrometry

Chemical research in toxicology, 2008-12, Vol.21 (12), p.2370-2378

2008

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Synthesis and mechanistic studies of a mitomycin dimer containing an eight-membered cyclic disulfide

Bioorganic & medicinal chemistry, 2011-07, Vol.19 (13), p.4004-4013

2011

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Mitomycinoid Alkaloids: Mechanism of Action, Biosynthesis, Total Syntheses, and Synthetic Approaches

Chemical reviews, 2013-08, Vol.113 (8), p.6816-6863

2013

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Reductive activation of mitomycins A and C by vitamin C

Bioorganic chemistry, 2013-06, Vol.48, p.1-7

Paz, Manuel M.

2013

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Targeting of pegylated liposomal mitomycin-C prodrug to the folate receptor of cancer cells: Intracellular activation and enhanced cytotoxicity

Journal of controlled release, 2016-03, Vol.225, p.87-95

2016

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Conjugating Aptamer and Mitomycin C with Reductant-Responsive Linker Leading to Synergistically Enhanced Anticancer Effect

Journal of the American Chemical Society, 2020-02, Vol.142 (5), p.2532-2540

2020

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Synthesis of an Oligodeoxyribonucleotide Adduct of Mitomycin C by the Postoligomerization Method via a Triamino Mitosene

Journal of the American Chemical Society, 2008-07, Vol.130 (29), p.9556-9565

2008

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Controlled release of Mitomycin C from modified cellulose based thermo-gel prevents post-operative de novo peritoneal adhesion

Carbohydrate polymers, 2020-02, Vol.229, p.115552-115552, Article 115552

2020

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Reaction of reductively activated mitomycin C with aqueous bicarbonate: Isolation and characterization of an oxazolidinone derivative of cis-1-hydroxy-2,7-diaminomitosene

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (1), p.31-34

Paz, Manuel M.

2010

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Droplet microfluidic technology for single-cell high-throughput screening

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (34), p.14195-14200

2009

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Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin

Chemical reviews, 2005-02, Vol.105 (2), p.739-758

2005

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Structural Basis of Substrate Recognition by the Postmitosane Modification Enzyme MitM in Mitomycin Biosynthesis

Biochemistry (Easton), 2024-09, Vol.63 (17), p.2217-2224

2024

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Development of Both Methotrexate and Mitomycin C Loaded PEGylated Chitosan Nanoparticles for Targeted Drug Codelivery and Synergistic Anticancer Effect

ACS applied materials & interfaces, 2014-07, Vol.6 (14), p.11413-11423

2014

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Mitomycin Dimers: Polyfunctional Cross-Linkers of DNA

Journal of medicinal chemistry, 2004-06, Vol.47 (12), p.3308-3319

2004

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Phytosomes Loaded with Mitomycin C–Soybean Phosphatidylcholine Complex Developed for Drug Delivery

Molecular pharmaceutics, 2013-01, Vol.10 (1), p.90-101

2013

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Analysis of a Parallel Branch in the Mitomycin Biosynthetic Pathway Involving the mitN-Encoded Aziridine N-Methyltransferase

The Journal of biological chemistry, 2007-07, Vol.282 (29), p.20941-20947

2007

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Self-Assembled Nanoparticles Based on Amphiphilic Anticancer Drug–Phospholipid Complex for Targeted Drug Delivery and Intracellular Dual-Controlled Release

ACS applied materials & interfaces, 2015-08, Vol.7 (32), p.17573-17581

2015

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Insight Into Factors Governing Formation, Synthesis and Stereochemical Configuration of DNA Adducts Formed by Mitomycins

Chemical record, 2023-01, Vol.23 (1), p.e202200193-n/a

2023

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Optimization of intrinsic and extrinsic tendon healing through controllable water-soluble mitomycin-C release from electrospun fibers by mediating adhesion-related gene expression

Biomaterials, 2015-08, Vol.61, p.61-74

2015

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Comparative Error-Free and Error-Prone Translesion Synthesis of N(2)-2'-Deoxyguanosine Adducts Formed by Mitomycin C and Its Metabolite, 2,7-Diaminomitosene, in Human Cells

Cytotoxicity, crosslinking and biological activity of three mitomycins

Interdependent Sequence Selectivity and Diastereoselectivity in the Alkylation of DNA by Decarbamoylmitomycin C

Synthesis-Enabled Probing of Mitosene Structural Space Leads to Improved IC50 over Mitomycin C

Synthesis of Mitomycin C and Decarbamoylmitomycin C N(2) deoxyguanosine-adducts

Synthesis of a major mitomycin C DNA adduct via a triaminomitosene

Mapping DNA Adducts of Mitomycin C and Decarbamoyl Mitomycin C in Cell Lines Using Liquid Chromatography/Electrospray Tandem Mass Spectrometry

Synthesis and mechanistic studies of a mitomycin dimer containing an eight-membered cyclic disulfide

Mitomycinoid Alkaloids: Mechanism of Action, Biosynthesis, Total Syntheses, and Synthetic Approaches

Reductive activation of mitomycins A and C by vitamin C

Targeting of pegylated liposomal mitomycin-C prodrug to the folate receptor of cancer cells: Intracellular activation and enhanced cytotoxicity

Conjugating Aptamer and Mitomycin C with Reductant-Responsive Linker Leading to Synergistically Enhanced Anticancer Effect

Synthesis of an Oligodeoxyribonucleotide Adduct of Mitomycin C by the Postoligomerization Method via a Triamino Mitosene

Controlled release of Mitomycin C from modified cellulose based thermo-gel prevents post-operative de novo peritoneal adhesion

Reaction of reductively activated mitomycin C with aqueous bicarbonate: Isolation and characterization of an oxazolidinone derivative of cis-1-hydroxy-2,7-diaminomitosene

Droplet microfluidic technology for single-cell high-throughput screening

Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin

Structural Basis of Substrate Recognition by the Postmitosane Modification Enzyme MitM in Mitomycin Biosynthesis

Development of Both Methotrexate and Mitomycin C Loaded PEGylated Chitosan Nanoparticles for Targeted Drug Codelivery and Synergistic Anticancer Effect

Mitomycin Dimers: Polyfunctional Cross-Linkers of DNA

Phytosomes Loaded with Mitomycin C–Soybean Phosphatidylcholine Complex Developed for Drug Delivery

Analysis of a Parallel Branch in the Mitomycin Biosynthetic Pathway Involving the mitN-Encoded Aziridine N-Methyltransferase

Self-Assembled Nanoparticles Based on Amphiphilic Anticancer Drug–Phospholipid Complex for Targeted Drug Delivery and Intracellular Dual-Controlled Release

Insight Into Factors Governing Formation, Synthesis and Stereochemical Configuration of DNA Adducts Formed by Mitomycins

Optimization of intrinsic and extrinsic tendon healing through controllable water-soluble mitomycin-C release from electrospun fibers by mediating adhesion-related gene expression

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