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Transfer of benzo[a]pyrene from microplastics to Artemia nauplii and further to zebrafish via a trophic food web experiment: CYP1A induction and visual tracking of persistent organic pollutants

Environmental toxicology and chemistry, 2016-07, Vol.35 (7), p.1656-1666

2016

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Expression of hepatic drug-metabolizing cytochrome p450 enzymes and their intercorrelations: a meta-analysis

Drug metabolism and disposition, 2014-08, Vol.42 (8), p.1349-1356

2014

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Comparative Proteomics Analysis of Human Liver Microsomes and S9 Fractions

Drug metabolism and disposition, 2020-01, Vol.48 (1), p.31-40

2020

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Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1138-1166

2019

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Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver

Clinical pharmacology and therapeutics, 2019-01, Vol.105 (1), p.131-141

2019

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Environmentally relevant organophosphate triesters in herring gulls: In vitro biotransformation and kinetics and diester metabolite formation using a hepatic microsomal assay

Toxicology and applied pharmacology, 2016-10, Vol.308, p.59-65

2016

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Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune Diseases

Journal of medicinal chemistry, 2020-11, Vol.63 (22), p.13561-13577

2020

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A Highly Selective Ratiometric Two-Photon Fluorescent Probe for Human Cytochrome P450 1A

Journal of the American Chemical Society, 2015-11, Vol.137 (45), p.14488-14495

2015

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Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

Drug metabolism and disposition, 2017-02, Vol.45 (2), p.216-223

2017

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Inhibition of soluble epoxide hydrolase by natural isothiocyanates

Biochemical and biophysical research communications, 2024-09, Vol.725, p.150261, Article 150261

2024

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Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities

Drug metabolism and disposition, 2012-01, Vol.40 (1), p.83-92

2012

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The pharmacokinetics, metabolism, and clearance mechanisms of tofacitinib, a janus kinase inhibitor, in humans

Drug metabolism and disposition, 2014-04, Vol.42 (4), p.759-773

2014

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Influence of metabolism on endocrine activities of bisphenol S

Chemosphere (Oxford), 2016-08, Vol.157, p.152-159

2016

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Prediction of human intestinal first-pass metabolism of 25 CYP3A substrates from in vitro clearance and permeability data

Drug metabolism and disposition, 2010-07, Vol.38 (7), p.1147-1158

2010

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The impact of CYP3A4 genetic polymorphism on crizotinib metabolism and drug-drug interactions

Toxicology and applied pharmacology, 2024-08, Vol.489, p.117016, Article 117016

2024

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Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite

Drug metabolism and disposition, 2010-01, Vol.38 (1), p.92-99

2010

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Diet-induced obese alters the expression and function of hepatic drug-metabolizing enzymes and transporters in rats

Biochemical pharmacology, 2019-06, Vol.164, p.368-376

2019

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Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans

Biochemical pharmacology, 2022-03, Vol.197, p.114887-114887, Article 114887

2022

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Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors

Drug metabolism and disposition, 2012-05, Vol.40 (5), p.1051-1065

2012

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Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice

Chemical research in toxicology, 2021-09, Vol.34 (9), p.2145-2156

2021

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In vitro metabolism of 2-ethylhexyldiphenyl phosphate (EHDPHP) by human liver microsomes

Toxicology letters, 2015-01, Vol.232 (1), p.203-212

2015

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Validated assays for human cytochrome P450 activities

Drug metabolism and disposition, 2004-06, Vol.32 (6), p.647-660

2004

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Proteomic Quantification of Changes in Abundance of Drug-Metabolizing Enzymes and Drug Transporters in Human Liver Cirrhosis: Different Methods, Similar Outcomes

Drug metabolism and disposition, 2021-08, Vol.49 (8), p.610-618

2021

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Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment

Antimicrobial agents and chemotherapy, 2016-09, Vol.60 (9), p.5285-5293

2016

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Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes

Life sciences (1973), 2011-08, Vol.89 (5), p.165-170

2011

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Transfer of benzo[a]pyrene from microplastics to Artemia nauplii and further to zebrafish via a trophic food web experiment: CYP1A induction and visual tracking of persistent organic pollutants

Expression of hepatic drug-metabolizing cytochrome p450 enzymes and their intercorrelations: a meta-analysis

Comparative Proteomics Analysis of Human Liver Microsomes and S9 Fractions

Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors

Age‐ and Genotype‐Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate‐Glucuronosyltransferases in Human Liver

Environmentally relevant organophosphate triesters in herring gulls: In vitro biotransformation and kinetics and diester metabolite formation using a hepatic microsomal assay

Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune Diseases

A Highly Selective Ratiometric Two-Photon Fluorescent Probe for Human Cytochrome P450 1A

Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants

Inhibition of soluble epoxide hydrolase by natural isothiocyanates

Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities

The pharmacokinetics, metabolism, and clearance mechanisms of tofacitinib, a janus kinase inhibitor, in humans

Influence of metabolism on endocrine activities of bisphenol S

Prediction of human intestinal first-pass metabolism of 25 CYP3A substrates from in vitro clearance and permeability data

The impact of CYP3A4 genetic polymorphism on crizotinib metabolism and drug-drug interactions

Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite

Diet-induced obese alters the expression and function of hepatic drug-metabolizing enzymes and transporters in rats

Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans

Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors

Exposure to an Environmental Mixture of Polycyclic Aromatic Hydrocarbons Induces Hepatic Cytochrome P450 Enzymes in Mice

In vitro metabolism of 2-ethylhexyldiphenyl phosphate (EHDPHP) by human liver microsomes

Validated assays for human cytochrome P450 activities

Proteomic Quantification of Changes in Abundance of Drug-Metabolizing Enzymes and Drug Transporters in Human Liver Cirrhosis: Different Methods, Similar Outcomes

Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment

Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes

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