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Role of MGMT in Tumor Development, Progression, Diagnosis, Treatment and Prognosis

Anticancer research, 2009-10, Vol.29 (10), p.3759-3768

2009

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20(S)‐ginsenoside‐Rg3 reverses temozolomide resistance and restrains epithelial‐mesenchymal transition progression in glioblastoma

Cancer science, 2019-01, Vol.110 (1), p.389-400

2019

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O(6)-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry

Biochimica et biophysica acta, 2011-12, Vol.1816 (2), p.179

2011

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Radiomics signature: A potential biomarker for the prediction of MGMT promoter methylation in glioblastoma

Journal of magnetic resonance imaging, 2018-05, Vol.47 (5), p.1380-1387

2018

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Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression

Cell death & disease, 2022-04, Vol.13 (4), p.293-12, Article 293

2022

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Resveratrol restores sensitivity of glioma cells to temozolamide through inhibiting the activation of Wnt signaling pathway

Journal of cellular physiology, 2019-05, Vol.234 (5), p.6783-6800

2019

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The Evolution of SNAP-Tag Labels

Biomacromolecules, 2023-02, Vol.24 (2), p.517-530

2023

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Chemotherapy sensitization of glioblastoma by focused ultrasound-mediated delivery of therapeutic liposomes

Journal of controlled release, 2019-02, Vol.295, p.130-139

2019

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BET protein inhibition sensitizes glioblastoma cells to temozolomide treatment by attenuating MGMT expression

Cell death & disease, 2022-12, Vol.13 (12), p.1037-12, Article 1037

2022

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Fluorescent molecular rotors detect O 6 -methylguanine dynamics and repair in duplex DNA

Chemical communications (Cambridge, England), 2024-01, Vol.60 (9), p.1156-1159

2024

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SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma

International journal of cancer, 2014-12, Vol.135 (11), p.2711-2720

2014

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O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas

Cell death & disease, 2013-10, Vol.4 (10), p.e876-e876

2013

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Temozolomide Followed by Combination With Low-Dose Ipilimumab and Nivolumab in Patients With Microsatellite-Stable, O 6 -Methylguanine-DNA Methyltransferase-Silenced Metastatic Colorectal Cancer: The MAYA Trial

Journal of clinical oncology, 2022-05, Vol.40 (14), p.1562-1573

2022

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A combined treatment regimen of MGMT-modified γδ T cells and temozolomide chemotherapy is effective against primary high grade gliomas

Scientific reports, 2021-10, Vol.11 (1), p.21133-8, Article 21133

2021

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Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag

Biochemistry (Easton), 2021-08, Vol.60 (33), p.2560-2575

2021

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DNA repair mechanisms in dividing and non-dividing cells

DNA repair, 2013-08, Vol.12 (8), p.620-636

2013

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Multifaceted Roles of Alkyltransferase and Related Proteins in DNA Repair, DNA Damage, Resistance to Chemotherapy, and Research Tools

Chemical research in toxicology, 2011-05, Vol.24 (5), p.618-639

Pegg, Anthony E

2011

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Prognostic value of O‐6‐methylguanine–DNA methyltransferase (MGMT) protein expression in glioblastoma excluding nontumour cells from the analysis

Neuropathology and applied neurobiology, 2018-02, Vol.44 (2), p.172-184

2018

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Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1

Scientific reports, 2018-03, Vol.8 (1), p.5087-12, Article 5087

2018

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Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells

ACS applied materials & interfaces, 2023-01, Vol.15 (1), p.106-119

2023

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Development of SNAP-Tag Fluorogenic Probes for Wash-Free Fluorescence Imaging

Chembiochem : a European journal of chemical biology, 2011-09, Vol.12 (14), p.2217-2226

2011

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Tumour‐associated microglia/macrophages predict poor prognosis in high‐grade gliomas and correlate with an aggressive tumour subtype

Neuropathology and applied neurobiology, 2018-02, Vol.44 (2), p.185-206

2018

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EPIC-0307-mediated selective disruption of PRADX–EZH2 interaction and enhancement of temozolomide sensitivity to glioblastoma via inhibiting DNA repair and MGMT

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (11), p.1976-1988

2023

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A modified nucleoside O6-methyl-2'-deoxyguanosine-5'-triphosphate exhibits anti-glioblastoma activity in a caspase-independent manner

Pharmacological research, 2024-01, Vol.199, p.106990-106990, Article 106990

2024

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Role of MGMT in Tumor Development, Progression, Diagnosis, Treatment and Prognosis

20(S)‐ginsenoside‐Rg3 reverses temozolomide resistance and restrains epithelial‐mesenchymal transition progression in glioblastoma

O(6)-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry

Radiomics signature: A potential biomarker for the prediction of MGMT promoter methylation in glioblastoma

Class I HDAC overexpression promotes temozolomide resistance in glioma cells by regulating RAD18 expression

Resveratrol restores sensitivity of glioma cells to temozolamide through inhibiting the activation of Wnt signaling pathway

The Evolution of SNAP-Tag Labels

Chemotherapy sensitization of glioblastoma by focused ultrasound-mediated delivery of therapeutic liposomes

BET protein inhibition sensitizes glioblastoma cells to temozolomide treatment by attenuating MGMT expression

Fluorescent molecular rotors detect O 6 -methylguanine dynamics and repair in duplex DNA

SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma

O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas

Temozolomide Followed by Combination With Low-Dose Ipilimumab and Nivolumab in Patients With Microsatellite-Stable, O 6 -Methylguanine-DNA Methyltransferase-Silenced Metastatic Colorectal Cancer: The MAYA Trial

A combined treatment regimen of MGMT-modified γδ T cells and temozolomide chemotherapy is effective against primary high grade gliomas

Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag

DNA repair mechanisms in dividing and non-dividing cells

Multifaceted Roles of Alkyltransferase and Related Proteins in DNA Repair, DNA Damage, Resistance to Chemotherapy, and Research Tools

Prognostic value of O‐6‐methylguanine–DNA methyltransferase (MGMT) protein expression in glioblastoma excluding nontumour cells from the analysis

Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1

Iron Oxide Nanoparticles Decorated with Functional Peptides for a Targeted siRNA Delivery to Glioma Cells

Development of SNAP-Tag Fluorogenic Probes for Wash-Free Fluorescence Imaging

Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients

Tumour‐associated microglia/macrophages predict poor prognosis in high‐grade gliomas and correlate with an aggressive tumour subtype

EPIC-0307-mediated selective disruption of PRADX–EZH2 interaction and enhancement of temozolomide sensitivity to glioblastoma via inhibiting DNA repair and MGMT

A modified nucleoside O6-methyl-2'-deoxyguanosine-5'-triphosphate exhibits anti-glioblastoma activity in a caspase-independent manner

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