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Formation of a Snf1-Mec1-Atg1 Module on Mitochondria Governs Energy Deprivation-Induced Autophagy by Regulating Mitochondrial Respiration

Developmental cell, 2017-04, Vol.41 (1), p.59-71.e4

2017

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Sch9S6K controls DNA repair and DNA damage response efficiency in aging cells

Cell reports (Cambridge), 2024-06, Vol.43 (6), p.114281, Article 114281

2024

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Signaling pathways involved in cell cycle arrest during the DNA breaks

DNA repair, 2021-02, Vol.98, p.103047-103047, Article 103047

2021

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Mec1 Modulates Interhomolog Crossover and Interplays with Tel1 at Post Double-Strand Break Stages

Journal of microbiology and biotechnology, 2020-03, Vol.30 (3), p.469-475

2020

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TORC1, Tel1/Mec1, and Mpk1 regulate autophagy induction after DNA damage in budding yeast

Cellular signalling, 2019-10, Vol.62, p.109344-109344, Article 109344

2019

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Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication

Molecular cell, 2020-05, Vol.78 (3), p.396-410.e4

2020

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Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis

Developmental cell, 2018-08, Vol.46 (4), p.495-503.e2

2018

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Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling

Genes & development, 2018-06, Vol.32 (11-12), p.822-835

2018

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The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage

The EMBO journal, 2001-07, Vol.20 (13), p.3544-3553

2001

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The structure of the checkpoint clamp 9-1-1 complex and clamp loader Rad24-RFC in Saccharomyces cerevisiae

Biochemical and biophysical research communications, 2019-08, Vol.515 (4), p.688-692

Liu, Wei

2019

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Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage

Genes & development, 2013-09, Vol.27 (18), p.1999-2008

2013

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DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1

The EMBO journal, 2003-08, Vol.22 (16), p.4325-4336

2003

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Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover

The EMBO journal, 2013-04, Vol.32 (8), p.1155-1167

2013

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Mec1ATR Autophosphorylation and Ddc2ATRIP Phosphorylation Regulates DNA Damage Checkpoint Signaling

Cell reports (Cambridge), 2019-07, Vol.28 (4), p.1090-1102.e3

2019

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Mec1 regulates PAS recruitment of Atg13 via direct binding with Atg13 during glucose starvation-induced autophagy

Proceedings of the National Academy of Sciences - PNAS, 2023-01, Vol.120 (1), p.e2215126120-e2215126120

2023

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The DNA damage checkpoint response to replication stress: A Game of Forks

Frontiers in genetics, 2013, Vol.4, p.26-26

2013

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S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion

Cellular and molecular life sciences : CMLS, 2017-07, Vol.74 (13), p.2361-2380

2017

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Surviving the breakup: the DNA damage checkpoint

Annual review of genetics, 2006-01, Vol.40 (1), p.209-235

2006

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Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases

Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (25), p.10364-10369

2007

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A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress

The EMBO journal, 2021-11, Vol.40 (21), p.e108439-n/a

2021

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Activation of ATR-related protein kinase upon DNA damage recognition

Current genetics, 2020-04, Vol.66 (2), p.327-333

2020

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Rad53 arrests leading and lagging strand DNA synthesis via distinct mechanisms in response to DNA replication stress

BioEssays, 2022-09, Vol.44 (9), p.e2200061-n/a

2022

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Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM)

Critical reviews in biochemistry and molecular biology, 2021-09, Vol.56 (5), p.441-454

2021

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Phosphoproteomics reveals a distinctive Mec1/ATR signaling response upon DNA end hyper‐resection

The EMBO journal, 2021-05, Vol.40 (10), p.e104566-n/a

2021

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Coupling end resection with the checkpoint response at DNA double-strand breaks

Cellular and Molecular Life Sciences, 2016-10, Vol.73 (19), p.3655-3663

2016

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Formation of a Snf1-Mec1-Atg1 Module on Mitochondria Governs Energy Deprivation-Induced Autophagy by Regulating Mitochondrial Respiration

Sch9S6K controls DNA repair and DNA damage response efficiency in aging cells

Signaling pathways involved in cell cycle arrest during the DNA breaks

Mec1 Modulates Interhomolog Crossover and Interplays with Tel1 at Post Double-Strand Break Stages

TORC1, Tel1/Mec1, and Mpk1 regulate autophagy induction after DNA damage in budding yeast

Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication

Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis

Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling

The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage

The structure of the checkpoint clamp 9-1-1 complex and clamp loader Rad24-RFC in Saccharomyces cerevisiae

Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage

DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1

Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover

Mec1ATR Autophosphorylation and Ddc2ATRIP Phosphorylation Regulates DNA Damage Checkpoint Signaling

Mec1 regulates PAS recruitment of Atg13 via direct binding with Atg13 during glucose starvation-induced autophagy

The DNA damage checkpoint response to replication stress: A Game of Forks

S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion

Surviving the breakup: the DNA damage checkpoint

Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases

A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress

Activation of ATR-related protein kinase upon DNA damage recognition

Rad53 arrests leading and lagging strand DNA synthesis via distinct mechanisms in response to DNA replication stress

Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM)

Phosphoproteomics reveals a distinctive Mec1/ATR signaling response upon DNA end hyper‐resection

Coupling end resection with the checkpoint response at DNA double-strand breaks

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