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Sponge's Molecular Diversity Through the Ambivalent Reactivity of 2-Aminoimidazole: A Universal Chemical Pathway to the Oroidin-Based Pyrrole-Imidazole Alkaloids and Their Palau'amine Congeners

European journal of organic chemistry, 2001-01, Vol.2001 (2), p.237-243

2001

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Marine Indole Alkaloids-Isolation, Structure and Bioactivities

Marine drugs, 2021-11, Vol.19 (12), p.658

2021

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Marine Alkaloids with Anti-Inflammatory Activity: Current Knowledge and Future Perspectives

Marine drugs, 2020-03, Vol.18 (3), p.147

2020

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Tryptophan derived natural marine alkaloids and synthetic derivatives as promising antimicrobial agents

European journal of medicinal chemistry, 2021-01, Vol.209, p.112945-112945, Article 112945

2021

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Synthesis, anticancer evaluation and molecular docking studies of 2,5-bis(indolyl)-1,3,4-oxadiazoles, Nortopsentin analogues

Journal of molecular structure, 2020-05, Vol.1208, p.127875, Article 127875

2020

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Anticancer potential of active alkaloids and synthetic analogs derived from marine invertebrates

European journal of medicinal chemistry, 2024-12, Vol.279, p.116850, Article 116850

2024

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Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification

European journal of medicinal chemistry, 2022-04, Vol.234, p.114233-114233, Article 114233

2022

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Natural Alkaloids as Multi-Target Compounds towards Factors Implicated in Alzheimer's Disease

International journal of molecular sciences, 2023-02, Vol.24 (5), p.4399

2023

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Integrated bioinformatics–cheminformatics approach toward locating pseudo‐potential antiviral marine alkaloids against SARS‐CoV‐2‐Mpro

Proteins, structure, function, and bioinformatics, 2022-09, Vol.90 (9), p.1617-1633

2022

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Marine Alkaloids: Compounds with In Vivo Activity and Chemical Synthesis

Marine drugs, 2021-06, Vol.19 (7), p.374

2021

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Synthesis of sulfur-containing polybromoindoles from the marine alga Laurencia brongniartii

Tetrahedron letters, 2023-10, Vol.129, p.154724, Article 154724

2023

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Protective Effects of Marine Alkaloid Neolamellarin A Derivatives against Glutamate Induced PC12 Cell Apoptosis

Marine drugs, 2022-04, Vol.20 (4), p.262

2022

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Nortopsentins as Leads from Marine Organisms for Anticancer and Anti-Inflammatory Agent Development

Molecules (Basel, Switzerland), 2023-09, Vol.28 (18), p.6450

2023

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1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A

European journal of medicinal chemistry, 2021-01, Vol.209, p.112892-112892, Article 112892

2021

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Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation

Molecules (Basel, Switzerland), 2020-12, Vol.26 (1), p.81

2020

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Hemimycalins C-E; Cytotoxic and Antimicrobial Alkaloids with Hydantoin and 2-Iminoimidazolidin-4-one Backbones from the Red Sea Marine Sponge Hemimycale sp

Marine drugs, 2021-12, Vol.19 (12), p.691

2021

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Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs

Marine drugs, 2016-12, Vol.14 (12), p.226-226

2016

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Morpho‐functional analyses reveal that changes in the chemical structure of a marine bisindole alkaloid alter the cytotoxic effect of its derivatives

Microscopy research and technique, 2022-07, Vol.85 (7), p.2381-2389

2022

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3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin analogues with antiproliferative activity

Marine drugs, 2015-04, Vol.13 (4), p.1901-1924

2015

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Total Synthesis of (−)‐Spiroleucettadine

Angewandte Chemie International Edition, 2017-11, Vol.56 (46), p.14663-14666

International ed. in English, 2017

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New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity

Marine drugs, 2019-01, Vol.17 (1), p.35

2019

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IDO1 and TDO inhibitory evaluation of analogues of the marine pyrroloiminoquinone alkaloids: Wakayin and Tsitsikammamines

Bioorganic & medicinal chemistry letters, 2021-05, Vol.40, p.127910-127910, Article 127910

2021

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Computational calculations and molecular docking studies on 2-(2-ethylaminothiazol-5-oyl)benzothiazole

Indian journal of chemistry. Sect. B. Organic chemistry, including medicinal chemistry, 2021-02, Vol.60 (2)

2021

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Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues

European journal of medicinal chemistry, 2017-09, Vol.138, p.371-383

2017

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The therapeutic potential and application of marine alkaloids in treating breast cancer

Frontiers in Marine Science, 2024-07, Vol.11

2024

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Sponge's Molecular Diversity Through the Ambivalent Reactivity of 2-Aminoimidazole: A Universal Chemical Pathway to the Oroidin-Based Pyrrole-Imidazole Alkaloids and Their Palau'amine Congeners

Marine Indole Alkaloids-Isolation, Structure and Bioactivities

Marine Alkaloids with Anti-Inflammatory Activity: Current Knowledge and Future Perspectives

Tryptophan derived natural marine alkaloids and synthetic derivatives as promising antimicrobial agents

Synthesis, anticancer evaluation and molecular docking studies of 2,5-bis(indolyl)-1,3,4-oxadiazoles, Nortopsentin analogues

Anticancer potential of active alkaloids and synthetic analogs derived from marine invertebrates

Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification

Natural Alkaloids as Multi-Target Compounds towards Factors Implicated in Alzheimer's Disease

Integrated bioinformatics–cheminformatics approach toward locating pseudo‐potential antiviral marine alkaloids against SARS‐CoV‐2‐Mpro

Marine Alkaloids: Compounds with In Vivo Activity and Chemical Synthesis

Synthesis of sulfur-containing polybromoindoles from the marine alga Laurencia brongniartii

Protective Effects of Marine Alkaloid Neolamellarin A Derivatives against Glutamate Induced PC12 Cell Apoptosis

Nortopsentins as Leads from Marine Organisms for Anticancer and Anti-Inflammatory Agent Development

1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A

Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation

Hemimycalins C-E; Cytotoxic and Antimicrobial Alkaloids with Hydantoin and 2-Iminoimidazolidin-4-one Backbones from the Red Sea Marine Sponge Hemimycale sp

Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs

Morpho‐functional analyses reveal that changes in the chemical structure of a marine bisindole alkaloid alter the cytotoxic effect of its derivatives

3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin analogues with antiproliferative activity

Total Synthesis of (−)‐Spiroleucettadine

New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity

IDO1 and TDO inhibitory evaluation of analogues of the marine pyrroloiminoquinone alkaloids: Wakayin and Tsitsikammamines

Computational calculations and molecular docking studies on 2-(2-ethylaminothiazol-5-oyl)benzothiazole

Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues

The therapeutic potential and application of marine alkaloids in treating breast cancer

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